Results 61 to 70 of about 406,742 (279)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Foreigners as actors of Europeanisation

Politeja, 2021
The article presents the conceptualisations that constitute the theoretical basis of a new study pursuing sociological understanding of some major social changes which have affected Polish cities in recent years.
Fiorenzo Fantuz
doaj   +1 more source

Anchoring symbols to sensorimotor control [PDF]

, 2002
This paper investigates how robots may emerge a lexicon to communicate complex meanings about actions such as `I am going to the red target' using simple (one-word) utterances. The main issue of the paper concerns the way these complex meanings represent
Vogt, Paul
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

De Europa et Asia d’Enea Silvio Piccolomini : migrations, invasions, ancrages, un état des lieux de l’Europe au xve siècle

ILCEA, 2017
In his two works, De Europa and Asia, Enea Silvio Piccolomini analyzes the movements—invasions, migrations—of populations between the East and Europe. In the face of the dangers which the Turkish advance in Latin and Greek Europe represents (after the ...
Serge Stolf
doaj   +1 more source

Generalized Berreman's model of the elastic surface free energy of a nematic liquid crystal on a sawtoothed substrate [PDF]

, 2012
In this paper we present a generalization of Berreman's model for the elastic contribution to the surface free-energy density of a nematic liquid crystal in presence of a sawtooth substrate which favours homeotropic anchoring, as a function of the ...
C. A. Brebbia, J. M. Romero-Enrique, J. T. Katsikadelis, O. A. Rojas-Gómez, O. C. Zienkiewicz, P. G. de Gennes, P. M. Chaikin   +6 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The impacts of task complexity, overconfidence, confirmation bias, customer influence, and anchoring on variations in real estate valuations

International Journal of Strategic Property Management, 2022
Real estate valuation relies on real estate appraisers’ accurate assessments, which reflects the need to improve the objectivity of the valuation process.
Chun-Chang Lee, Hsueh-Yung Lee, Wen-Chih Yeh, Zheng Yu   +3 more
doaj   +1 more source

Anchoring Bias in Online Voting

, 2012
Voting online with explicit ratings could largely reflect people's preferences and objects' qualities, but ratings are always irrational, because they may be affected by many unpredictable factors like mood, weather, as well as other people's votes.
Alon N. Babaioff M. Karidi R. Lavi R. Tennenholtz M., Cen L., Goh K.-I., Huang J. Cheng X.-Q. Shen H.-W. Zhou T. Jin X., Koren Y. Sill J., Ren X.-Z., Shang M.-S., Tao Zhou, Vig J. Sen S. Riedl J., Yan X.-Y. Han X.-P. Wang B.-H. Zhou T., Zhou T., Zi-Ke Zhang, Zimo Yang   +12 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source