Results 71 to 80 of about 92,610 (252)

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

GSK3 Inhibition During Annelid Head Regeneration Results in a Hyper‐Proliferative Blastema and Impaired Differentiation

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
A whole‐body regenerative annelid was treated with a GSK3 inhibitor. While posterior regeneration was mostly normal, GSK3 inhibition prevented differentiation of anterior‐specific structures and instead produced a persistent, oversized, hyper‐proliferative blastema. This suggests that GSK3 promotes anterior identity and halts proliferation during axial
James D. Nowotny, Eduardo E. Zattara, Maria Balarezo, Kevin G. Nyberg, Kenna M. Costello, Alexandra E. Bely   +5 more
wiley   +1 more source

Holocene vegetation dynamics of Grande Terre (Kerguelen Islands) inferred from sedimentary ancient DNA

Journal of Quaternary Science, EarlyView.
ABSTRACT While the Antarctic region has experienced significant climatic changes over the Holocene, few high‐resolution records have examined their effects on the local biota. In order to understand past ecological shifts and forecast future changes, it is important to obtain high‐resolution palaeoecological records from this region.
Xaali O'Reilly‐Berkeley, Aloïs Revéret, Youri Lammers, Maaike Zwier, Anne E. Bjune, Fabien Arnaud, Jostein Bakke, Sandra Nogué, Inger G. Alsos   +8 more
wiley   +1 more source

Ancient DNA reveals genetic connections between early Di-Qiang and Han Chinese

BMC Evolutionary Biology, 2017
Background Ancient Di-Qiang people once resided in the Ganqing region of China, adjacent to the Central Plain area from where Han Chinese originated. While gene flow between the Di-Qiang and Han Chinese has been proposed, there is no evidence to support ...
Jiawei Li, Wen Zeng, Ye Zhang, Albert Min-Shan Ko, Chunxiang Li, Hong Zhu, Qiaomei Fu, Hui Zhou   +7 more
doaj   +1 more source

Macronutrient and micronutrient profiles of meat types: insights into human health and diet

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Despite considerable advances in global health and nutrition, emerging challenges such as population growth, climate change, and limited natural resources continue to threaten food security. Meat remains an essential component of the human diet, supplying high‐quality proteins, essential amino acids, lipids, vitamins, and minerals necessary ...
Özgül Anitaş, Serap Göncü, Fatma Hepsağ, Nazan Koluman, Yesim Ozogul   +4 more
wiley   +1 more source

First archaeological evidence for ginger consumption as a potential medicinal ingredient in a late medieval leprosarium at St Leonard, Peterborough, England

Scientific Reports
Leprosy was one of the most outwardly visible diseases in the European Middle Ages, a period during which leprosaria were founded to provide space for the sick.
Elena Fiorin, Charlotte A. Roberts, Marica Baldoni, Erin Connelly, Christina Lee, Claudio Ottoni, Emanuela Cristiani   +6 more
doaj   +1 more source

Early cave art and ancient DNA record the origin of European bison

Nature Communications, 2016
The ancestry of the European bison (wisent) remains a mystery. Here, Cooper and colleagues examine ancient DNA from fossil remains of extinct bison, and reveal the wisent originated through the hybridization of the extinct Steppe bison and ancestors of ...
Julien Soubrier, Graham Gower, Kefei Chen, Stephen M. Richards, Bastien Llamas, Kieren J. Mitchell, Simon Y. W. Ho, Pavel Kosintsev, Michael S. Y. Lee, Gennady Baryshnikov, Ruth Bollongino, Pere Bover, Joachim Burger, David Chivall, Evelyne Crégut-Bonnoure, Jared E. Decker, Vladimir B. Doronichev, Katerina Douka, Damien A. Fordham, Federica Fontana, Carole Fritz, Jan Glimmerveen, Liubov V. Golovanova, Colin Groves, Antonio Guerreschi, Wolfgang Haak, Tom Higham, Emilia Hofman-Kamińska, Alexander Immel, Marie-Anne Julien, Johannes Krause, Oleksandra Krotova, Frauke Langbein, Greger Larson, Adam Rohrlach, Amelie Scheu, Robert D. Schnabel, Jeremy F. Taylor, Małgorzata Tokarska, Gilles Tosello, Johannes van der Plicht, Ayla van Loenen, Jean-Denis Vigne, Oliver Wooley, Ludovic Orlando, Rafał Kowalczyk, Beth Shapiro, Alan Cooper   +47 more
doaj   +1 more source

Degradation of ancient DNA [PDF]

Current Biology, 1996
Kelman, Zvi, Moran, Lori
openaire   +2 more sources

Beyond Skin and Eyes: The Medical and Social Burden of Oculocutaneous Albinism in Africa: A Narrative Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Oculocutaneous albinism (OCA) is a genetic disorder found worldwide, but its impact is particularly pronounced in the African continent. This results from both a higher prevalence and the persistent myths and superstitions surrounding the condition in many African communities.
Rebecca Donadoni, Niccolò Capurro, Alessandro Svizzero, Valeria Brazzelli   +3 more
wiley   +1 more source

Is DNA metabarcoding an option for formaldehyde‐preserved zooplankton time series?

Limnology and Oceanography: Methods, EarlyView.
Abstract The recovery of amplifiable DNA from formaldehyde‐fixed (FF) zooplankton samples has long been considered problematic, but advances in degraded‐DNA retrieval have renewed interest in FF samples. To access the information stored in long‐term zooplankton time series, we evaluated methods for extracting amplifiable DNA from community samples ...
Aitor Albaina, Anders Lanzén, Irati Miguel, Fernando Rendo, María Santos   +4 more
wiley   +1 more source