Results 61 to 70 of about 2,093,063 (290)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

A 16th century Escherichia coli draft genome associated with an opportunistic bile infection

Communications Biology, 2022
Ancient DNA from an Italian mummy’s gallstone provides insight into opportunistic E. coli infection.
George S. Long, Jennifer Klunk, Ana T. Duggan, Madeline Tapson, Valentina Giuffra, Lavinia Gazzè, Antonio Fornaciari, Sebastian Duchene, Gino Fornaciari, Olivier Clermont, Erick Denamur, G. Brian Golding, Hendrik Poinar   +12 more
doaj   +1 more source

Checklist of the Mammal Collection Preserved at the University of Palermo under the Framework of the National Biodiversity Future Center

Diversity, 2023
The latest reorganization of the Vertebrate collections preserved at the “Pietro Doderlein” Museum of Zoology of the University of Palermo (Italy) has made it possible to draw up a check-list of the Mammal taxa present in the stuffed (M), fluid-preserved
Sabrina Lo Brutto, Antonina Badalucco, Rocco Iacovera, Elisabetta Cilli, Maurizio Sarà   +4 more
doaj   +1 more source

Archaeogenetics in Popular Media : Contemporary Implications of Ancient DNA

, 2019
If most academic debates surrounding the recent boom of ancient DNA (aDNA) so far have concerned conflicting research epistemologies, this article is a call for taking aspects of media and communication more seriously.
Nyblom, Andreas, Strand, Daniel,, Mulcare, Charlotte,, Källén, Anna, Mulcare, Charlotte, Strand, Daniel, Källén, Anna,, Nyblom, Andreas,   +7 more
core   +1 more source

A Complete Mitochondrial Genome Sequence from a Mesolithic Wild Aurochs (Bos primigenius) [PDF]

, 2010
Background The derivation of domestic cattle from the extinct wild aurochs (Bos primigenius) has been well-documented by archaeological and genetic studies.
Finlay Emma K., Park Stephen D. E., Daniel G Bradley, Shapiro Beth, Edwards Ceiridwen J., Ceiridwen J Edwards, Murphy, A., MacHugh David E., Beth Shapiro, Edwards, C.J., Bradley Daniel G., Park, S.D.E., MacHugh, D.E., McGettigan, Paul A., Shapiro, Beth, Alison Murphy, Martin B Richards, Chamberlain Andrew T., Loftus Brendan J., Murphy, Alison, Bradley, D.G., Knapp, Michael, David A Magee, Amanda J Lohan, Magee David A., Stephen D E Park, Lohan, A.J., Shapiro, B., Magee, David A., Bradley, Daniel G., Brendan J Loftus, Richards Martin B., Richards, M.B., Paul A McGettigan, Loftus, Brendan J., Park, Stephen D E, David E MacHugh, Chamberlain, Andrew T., Murphy Alison, MacHugh, David E., Andrew T Chamberlain, Park, Stephen D. E., Lohan, Amanda J., Lohan Amanda J., Loftus, B.J., Finlay, Emma K., McGettigan, P.A., Finlay, E.K., Richards, Martin B., Magee, D.A., Emma K Finlay, McGettigan Paul A., Chamberlain, A.T., Edwards, Ceiridwen J.   +53 more
core   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le, Anh Tuan Trong Tran, Ammara Waheed, Tran Thanh Tung, Dusan Losic   +4 more
wiley   +1 more source

Four millennia of long-term individual foraging site fidelity in a highly migratory marine predator

Communications Biology, 2022
Isotopic analyses of bone collagen from 95 archaeological short-tailed albatross specimens explore long-term patterns in foraging characteristics and individual foraging site fidelity of birds off of Vancouver Island.
Eric. J. Guiry, Margaretta James, Christina Cheung, Thomas C. A. Royle   +3 more
doaj   +1 more source

Using archaeogenomic and computational approaches to unravel the history of local adaptation in crops [PDF]

, 2014
Our understanding of the evolution of domestication has changed radically in the past 10 years, from a relatively simplistic rapid origin scenario to a protracted complex process in which plants adapted to the human environment.
Kitchen, James, Smith, Oliver, Ware, R., Allaby, Robin G., Smith, O., Gutaker, Rafał M., Allaby, R. G., Gutaker, R., Clarke, Andrew C., Palmer, Sarah A., Kitchen, J. L., Gutaker, Rafal, Pearson, Neil, Kitchen, James L., Clarke, A. C., Ware, Roselyn, Pearson, N.   +16 more
core   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Genome-wide diversity of Pagliarola sheep residual population and its conservation implication

Italian Journal of Animal Science, 2021
Local breeds represent an underestimated resource in terms not only of their important cultural and economical role in marginal areas, but also because they often own a potential genetic pool well adapted to extreme conditions. This fact is of increasing
Christian Persichilli, Gabriele Senczuk, Loi Pasqualino, Debora Agata Anzalone, Riccardo Negrini, Paolo Ajmone Marsan, Licia Colli, Fabio Pilla, Salvatore Mastrangelo   +8 more
doaj   +1 more source