Results 41 to 50 of about 2,093,063 (290)
Nature Communications, 2020 Pleistocene population dynamics can inform the consequences of current climate change. This phylogeography of 35 complete American mastodon mitochondrial genomes suggests distinct lineages in this species repeatedly expanded northwards and then went ...
Emil Karpinski +18 more
doaj +1 more source
Widespread occurrence of Mycobacterium tuberculosis DNA from 18th-19th century Hungarians [PDF]
, 2003 A large number (265) of burials from 1731-1838 were discovered in sealed crypts of the Dominican Church, Vac, Hungary in 1994. Many bodies were naturally mummified, so that both soft tissues and bones were available.
Spigelman, M +10 more
core +1 more source
Plagued by a cryptic clock: insight and issues from the global phylogeny of Yersinia pestis
Communications Biology, 2023 The emergence of the plague pathogen throughout history is investigated using molecular clock modelling and phylogenetic analyses.
Katherine Eaton +7 more
doaj +1 more source
Genealogy, 2023 The chronological period from the beginning of the Chalcolithic Age to the end of the Bronze Age on the Iberian northern sub-plateau of the Iberic Peninsula involves interesting social and cultural phenomena, such as the appearance of the Bell Beaker and,
Sara Palomo-Díez +4 more
doaj +1 more source
Pathogenic microbial ancient DNA: a problem or an opportunity? [PDF]
, 2005 Copyright © Royal Society 2006Eske Willerslev, Alan ...
Spigelman, M +7 more
core +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
‘The Farm Beneath the Sand’ – an archaeological case study on ancient ‘dirt’ DNA [PDF]
, 2009 It is probable that ‘The Farm Beneath the Sand’ will come to stand for a revolution in archaeological investigation. The authors show that a core of soil from an open field can provide a narrative of grazing animals, human occupation and their departure,
Heyn, P. +24 more
core
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Interrogation of modern and ancient genomes reveals the complex domestic history of cattle [PDF]
, 2014 The analysis of mitochondrial and nuclear DNA sequence polymorphisms from modern cattle populations has had a profound impact on our understanding of the events surrounding the domestication of cattle.
Magee, D. A. +2 more
core +1 more source