Results 21 to 30 of about 93,163 (299)

How Does Diet Influence Our Lives? Evaluating the Relationship between Isotopic Signatures and Mortality Patterns in Italian Roman Imperial and Medieval Periods

open access: yesMolecules, 2021
The present research investigates the relationship between dietary habits and mortality patterns in the Roman Imperial and Medieval periods. The reconstructions of population dynamics and subsistence strategies provide a fascinating source of information
Marica Baldoni   +4 more
doaj   +1 more source

Epigenetics of Ancient DNA [PDF]

open access: yesActa Naturae, 2016
Initially, the study of DNA isolated from ancient specimens had been based on the analysis of the primary nucleotide sequence. This approach has allowed researchers to study the evolutionary changes that occur in different populations and determine the influence of the environment on genetic selection.
ZHENILO S.V.   +2 more
openaire   +2 more sources

A quantitative approach to detect and overcome PCR inhibition in ancient DNA extracts

open access: yesBioTechniques, 2009
Inhibition is problematic in many applications of PCR, particularly those involving degraded or low amounts of template DNA, when simply diluting the extract is undesirable. Two basic approaches to monitoring inhibition in such samples using real-time or
Christine E. King   +4 more
doaj   +1 more source

Genetic characterisation of the North-West Indian populations: analysis of mitochondrial DNA control region variations

open access: yesAnnals of Human Biology, 2021
Background Human mitochondrial DNA presents several interesting characteristics, making it a favourable tool in the field of molecular anthropology, medical genetics, population history, and forensic science.
Gagandeep Singh   +5 more
doaj   +1 more source

Apolipoprotein E (APOE) Haplotypes in Healthy Subjects from Worldwide Macroareas: A Population Genetics Perspective for Cardiovascular Disease, Neurodegeneration, and Dementia

open access: yesCurrent Issues in Molecular Biology, 2023
Human APOE is a 299-amino acid long protein expressed and secreted in several tissues and body districts, where it exerts different functions mainly related to lipid metabolism, with specific activities around cholesterol transport and absorption ...
Paolo Abondio   +2 more
doaj   +1 more source

A new home for microbes

open access: yeseLife, 2019
Modern microorganisms growing in fossils provide major challenges for researchers trying to detect ancient molecules in the same fossils.
Raphael Eisenhofer, Alan Cooper
doaj   +1 more source

Indigenous sex-selective salmon harvesting demonstrates pre-contact marine resource management in Burrard Inlet, British Columbia, Canada

open access: yesScientific Reports, 2021
To gain insight into pre-contact Coast Salish fishing practices, we used new palaeogenetic analytical techniques to assign sex identifications to salmonid bones from four archaeological sites in Burrard Inlet (Tsleil-Waut), British Columbia, Canada ...
Jesse Morin   +10 more
doaj   +1 more source

Microbiome applications for pathology: challenges of low microbial biomass samples during diagnostic testing

open access: yesThe Journal of Pathology: Clinical Research, 2020
The human microbiome can play key roles in disease, and diagnostic testing will soon have the ability to examine these roles in the context of clinical applications.
Caitlin A Selway   +2 more
doaj   +1 more source

Genomic Approaches for Conservation Management in Australia under Climate Change

open access: yesLife, 2021
Conservation genetics has informed threatened species management for several decades. With the advent of advanced DNA sequencing technologies in recent years, it is now possible to monitor and manage threatened populations with even greater precision ...
Isabelle R. Onley   +2 more
doaj   +1 more source

Surveying the repair of ancient DNA from bones via high-throughput sequencing

open access: yesBioTechniques, 2015
DNA damage in the form of abasic sites, chemically altered nucleotides, and strand fragmentation is the foremost limitation in obtaining genetic information from many ancient samples. Upon cell death, DNA continues to endure various chemical attacks such
Nathalie Mouttham   +4 more
doaj   +1 more source

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