Results 21 to 30 of about 89,416 (252)

Sequencing ancient DNA [PDF]

Proceedings of the National Academy of Sciences, 2014
The well-preserved mummy of an old man (Upper) is displayed in an exhibition in Denmark’s National Museum. The mummy was removed, as displayed, from an excavation in 1875 at Borum Eshoj, near Aarhus, Denmark. Carpenter and colleagues used hair samples from the mummy to isolate ancient DNA and validate the technique.
openaire   +2 more sources

Genomic data suggest parallel dental vestigialization within the xenarthran radiation

Peer Community Journal, 2023
The recent influx of genomic data has provided greater insights into the molecular basis for regressive evolution, or vestigialization, through gene loss and pseudogenization.
Emerling, Christopher A, Gibb, Gillian C, Tilak, Marie-Ka, Hughes, Jonathan J, Kuch, Melanie, Duggan, Ana T, Poinar, Hendrik N, Nachman, Michael W, Delsuc, Frédéric   +8 more
doaj   +1 more source

Museomics Provides Insights into Conservation and Education: The Instance of an African Lion Specimen from the Museum of Zoology “Pietro Doderlein”

Diversity, 2023
Innovative technological approaches are crucial to enhance naturalistic museum collections and develop information repositories of relevant interest to science, such as threatened animal taxa.
Elisabetta Cilli, Francesco Fontani, Marta Maria Ciucani, Marcella Pizzuto, Pierangelo Di Benedetto, Sara De Fanti, Thomas Mignani, Carla Bini, Rocco Iacovera, Susi Pelotti, Filippo Spadola, Donata Luiselli, Sabrina Lo Brutto   +12 more
doaj   +1 more source

Stories in Ancient DNA [PDF]

BioTechniques, 2017
Technology developments are leading to rapid advances in ancient DNA analysis. Nathan Blow talks to researchers peering into the past through ancient DNA.
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Response to Brinkmann et al. “Re-assembly of 19th century smallpox vaccine genomes reveals the contemporaneous use of horsepox and horsepox-related viruses in the United States”

Genome Biology, 2020
We thank Brinkmann and colleagues for their correspondence and their further investigation into these American Civil War Era vaccination strains. Here, we summarize the difficulties and caveats of work with ancient DNA.
Ana T. Duggan, Edward C. Holmes, Hendrik N. Poinar   +2 more
doaj   +1 more source

Palaeomicrobiology: Application of Ancient DNA Sequencing to Better Understand Bacterial Genome Evolution and Adaptation

Frontiers in Ecology and Evolution, 2020
Next generation sequencing (NGS) has unlocked access to the wide range of non-cultivable microorganisms, including those present in the ancient past. The study of microorganisms from ancient sources (palaeomicrobiology) using DNA sequencing now provides ...
Luis A. Arriola, Alan Cooper, Alan Cooper, Laura S. Weyrich, Laura S. Weyrich, Laura S. Weyrich   +5 more
doaj   +1 more source

Impact of commercial RNA extraction methods on the recovery of human RNA sequence data from archival fixed tissues

BioTechniques
Archival fixed tissues hold key insights into the evolutionary history of RNA viruses and the associated host immune response, yet access to the RNA sequence data is limited by a lack of robust methods for RNA extraction and sequence retrieval from these
Tess Wilson, Melanie Kuch, Debi Poinar, Jasmine Rockarts, Bruce Wainman, Susan Morgello, Hendrik Poinar   +6 more
doaj   +1 more source

Quantitative PCR as a predictor of aligned ancient DNA read counts following targeted enrichment

BioTechniques, 2013
Targeted DNA enrichment through hybridization capture (EHC) is rapidly replacing PCR as the method of choice for enrichment prior to genomic resequencing.
Jacob Enk, Jean-Marie Rouillard, Hendrik Poinar   +2 more
doaj   +1 more source

The immunogenetic impact of European colonization in the Americas

Frontiers in Genetics, 2022
The introduction of pathogens originating from Eurasia into the Americas during early European contact has been associated with high mortality rates among Indigenous peoples, likely contributing to their historical and precipitous population decline ...
Evelyn Jane Collen, Angad Singh Johar, Angad Singh Johar, João C. Teixeira, João C. Teixeira, João C. Teixeira, Bastien Llamas, Bastien Llamas, Bastien Llamas, Bastien Llamas   +9 more
doaj   +1 more source

American mastodon mitochondrial genomes suggest multiple dispersal events in response to Pleistocene climate oscillations

Nature Communications, 2020
Pleistocene population dynamics can inform the consequences of current climate change. This phylogeography of 35 complete American mastodon mitochondrial genomes suggests distinct lineages in this species repeatedly expanded northwards and then went ...
Emil Karpinski, Dirk Hackenberger, Grant Zazula, Chris Widga, Ana T. Duggan, G. Brian Golding, Melanie Kuch, Jennifer Klunk, Christopher N. Jass, Pam Groves, Patrick Druckenmiller, Blaine W. Schubert, Joaquin Arroyo-Cabrales, William F. Simpson, John W. Hoganson, Daniel C. Fisher, Simon Y. W. Ho, Ross D. E. MacPhee, Hendrik N. Poinar   +18 more
doaj   +1 more source