Results 101 to 110 of about 379,136 (292)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Prompt interventions improve outcomes in conduct disorders [PDF]
, 2013 Dr Clare Taylor, and Professors Stephen Pilling and Stephen Scott explain the importance of early identification and care of children and young people with conduct ...
Scott, Stephen Basil Cuthbert +2 more
core +2 more sources
Strengths and difficulties questionnaire (SDQ): a study of school children in Ribeirão Preto
Brazilian Journal of Psychiatry, 2003 OBJECTIVE: The objective of this study is to investigate possible child psychiatric disorders using the strengths and difficulties questionnaire (SDQ).
Cury Camilo Ramos +1 more
doaj
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Prevention of conduct disorders: cognitive behavioural approaches
, 2013 Introduction The burden of conduct disorders Conduct disorders are characterised by persistent antisocial behaviour in children and young people and are remarkably common: at the level of diagnosable disorders, even using relatively conservative criteria,
Scott, Stephen, Stephen Scott
core +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Conduct disorders as a result of specific learning disorders
, 2012 This thesis focuses on relationship between specific learning disorders and conduct disorders in puberty. The theoretical part explains the basic terms apearing in the thesis such as specific learning disorders, conduct disorders, puberty and prevention ...
VOKROJOVÁ, Nela
core
Ecotoxicology and Environmental SafetyLead (Pb) exposure in children and adolescents poses a significant public health risk due to its potential neurotoxic effects. While high-level Pb exposure is known to impair learning and cognition, the behavioral and molecular consequences of low-level ...
Yeonghoon Son +6 more
doaj +1 more source