Results 131 to 140 of about 4,449,758 (301)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Islamic World Science Citation Center's Journal Citation Reports (JCR)

open access: yes, 2016
This article gives an overview of the Islamic World Science Citation Center's (ISC) Journal Citation Reports (JCR) database. ISC-JCR is the only source of citation data on Islamic countries’ leading journals and covers journals in English, Arabic and ...
Safahieh, Hajar; Regional information center for science and technology
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Science Literacy and Information Skills

open access: yesIssues in Science and Technology Librarianship, 1991
Gregg Sapp
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Analysis and Comparison of Interdisciplinary Relations of Library Science and Information Science Based on Citation Clustering in The Period of Before and After the Appearance of the Web

open access: yesIranian Journal of Information Processing & Management, 2016
The purpose of the present study was to analyze the interdisciplinary relations of “Library Science and Information Science”. For this purpose the subject categories of citing and cited journals of these fields were investigated in JCR ...
Farideh Osareh   +3 more
doaj  

Research and Science Today no. 2/2020

open access: yes
RESEARCH AND SCIENCE TODAY is a biannual science journal established in 2011. The journal is an informational platform that publishes assessment articles and the results of various scientific research carried out by academics.
Research and Science Today
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

La producción española en biblioteconomía y documentación (ISI 1995-2005)

Spanish literature in library and information science (isi 1995-2005)

open access: yesEncontros Bibli, 2006
La producción de un determinado país y una determinada disciplina en el ISI Web of Knowledge, es un claro indicador de la investigación de calidad que es capaz de generar ese país en esa disciplina.
Grupo Scimago
doaj  

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