Results 81 to 90 of about 4,449,758 (301)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

The research cluster as a means of improving library and information activities in a region

Библиосфера, 2013
Organizational problems of forming investigational cluster, as well as its potential advantages and disadvantages as an instrument for stimulating research work in libraries and information centers on regional level are considered.
G. V. Varganova
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The information literacy framework: case studies of successful implementation Association for Library and Information Science Education series./ edited by Heidi Julien, Melissa Gross, Don Latham.

, 2020
Includes bibliographical references and index."This edited book helps demystify how to incorporate ACRL's Framework for Information Literacy for Higher Education into information literacy instruction in higher education as well as how to teach the new ...
Gross Melissa, Latham Don, Julien (Heidi Elizabeth),   +2 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Information and knowledge: an evolutionary framework for information science

Information Research: An International Electronic Journal, 2005
Background. Many definitions of information, knowledge, and data have been suggested throughout the history of information science. In this article, the objective is to provide definitions that are usable for the physical, biological, and social meanings
Marcia J. Bates
doaj  

Forecasting the Subject Trend of International Library and Information Science Research by 2030 Using the Deep Learning Approach

, 2022
This study seeks to forecast the subject trend of library and information science research until 2030 based on modeling previous research topics in this field, which has been done with a text mining and in-depth learning approach.
Ghane, Mohammad Reza; Associate Prof. of LIS, Department of Evaluation and Collection Development, Regional Information Center for Science & Technology (RICeST), Shiraz, Iran, Ghanadi Nezhad, Farzaneh; Ph.D. Candidate in Knowledge and Information Science, Shahid Chamran University of Ahvaz,, Osareh, Farideh; Professor, Department of Knowledge and Information Science, Shahid Chamran University of Ahvaz, Ahvaz   +2 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The Place of Library Science and Information-Documentation Science in Information Science

, 1973
(The author) is German and is now considered one of the leading international scholars and specialists in information science. After being developed and transformed into the "Institute of Scientific Librarianship and Information" in 1966, the Institute of Librarianship at Humboldt University-Berlin organized a colloquium entitled "The Subject and ...
openaire   +2 more sources