Results 91 to 100 of about 11,825,582 (279)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Accelerating ethics, empathy, and equity in geographic information science. [PDF]

open access: yesProc Natl Acad Sci U S A, 2022
Nelson TA, Goodchild MF, Wright DJ.
europepmc   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Library and Information Science Internship

open access: yesPakistan Journal of Information Management & Libraries
This study explores whether Library and Information Science students from three universities who participated in experiential learning through internship programs have identical or different experiences during their internships under selected internship ...
Noel W. Cabfilan   +3 more
doaj  

The Naîure of Science and Librarianship and Information Science as a Disciplirıe of Science

open access: yesTürk Kütüphaneciliği, 1993
Science is a systemized from of knowledge which is a product of human creativity. The aim of this study is to try to explain the nature of the concept of science, and to evaluate librarianship and information science as a scientific discipline in ...
Oya Gürdal
doaj  

Linear preservers and quantum information science

open access: yes, 2012
Let $m,n\ge 2$ be positive integers, $M_m$ the set of $m\times m$ complex matrices and $M_n$ the set of $n\times n$ complex matrices. Regard $M_{mn}$ as the tensor space $M_m\otimes M_n$. Suppose $|\cdot|$ is the Ky Fan $k$-norm with $1 \le k \le mn$, or
Fosner, Ajda   +3 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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