Results 41 to 50 of about 1,342,075 (311)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Infrastructure, transport and productivity [PDF]
This information sheet reviews trends in Australian productivity with a focus on the transport sector. Well targeted investments in transport infrastructure result in productivity increases that benefit many other industries.
core
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Parallel hierarchical memory (PI memory) is a new type of memory that is designed to improve the performance of parallel computing systems. PI memory is composed of two blocks: a mask RAM and a tail element RAM.
Leonid Timchenko +7 more
doaj +1 more source
Experimental Investigation on Underlying Mechanism of LLDPE Based Rotationally Molded BioComposites
Large hollow seamless plastic products can be easily molded by rotational molding process. A determined thermal stability along with a broad processing window is some requisite variant requirement of resin needed to be incorporated for this technique ...
PL. Ramkumar +2 more
doaj +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
State of Australian cities 2014-2015: progress in Australian regions [PDF]
Provides insight into the vital role that Australian cities play in the growth of the countries economy and tracks the overall progress made in Australia\u27s major centres.
Department of Infrastructure and Regional Development (Australia)
core
Abstract Design, construction, maintenance and upgrading of civil engineering infrastructure requires fresh thinking to minimize use of materials, energy and labour. This can only be achieved by understanding the performance of the infrastructure, both during its construction and throughout its design life, through innovative ...
Soga, Kenichi, Schooling, Jennifer
openaire +4 more sources
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source

