Results 51 to 60 of about 1,928,713 (304)

Infrastructure, transport and productivity [PDF]

, 2014
This information sheet reviews trends in Australian productivity with a focus on the transport sector. Well targeted investments in transport infrastructure result in productivity increases that benefit many other industries.

core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Architectures & Infrastructure

, 2010
The third of the S-Cube technology layers provides infrastructure capabilities for defining basic communication patterns and interactions involving as well as providing facilities for providing, for example, contextual and qualitative information about a service's and their client's environment and performance.
F André, I Brandic, E Daubert, G Gauvrit, M Giordano, G Kecskemeti, A Kertész, C Di Napoli, Németh Z, JL Pazat, H Psaier, W Renz, J Sudeikat   +12 more
openaire   +3 more sources

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

ARCHITECTURAL AND STRUCTURAL AND FUNCTIONAL FEATURES OF THE ORGANIZATION OF PARALLEL-HIERARCHICAL MEMORY

Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska
Parallel hierarchical memory (PI memory) is a new type of memory that is designed to improve the performance of parallel computing systems. PI memory is composed of two blocks: a mask RAM and a tail element RAM.
Leonid Timchenko, Natalia Kokriatska, Volodymyr Tverdomed, Iryna Yepifanova, Yurii Didenko, Dmytro Zhuk, Maksym Kozyr, Iryna Shakhina   +7 more
doaj   +1 more source

Evaluation of Interface Shear Strength of Natural Kenaf Geogrid and Recycled Concrete Aggregate for Sustainable Pavement Applications

Journal of Natural Fibers, 2022
In this research, a natural kenaf geogrid was used to reinforce recycled concrete aggregate (RCA) as a base/subbase material. The interface shear behavior of kenaf geogrid-reinforced RCA was investigated using a large-scale direct shear test (LSDT).
Apichat Suddeepong, Menglim Hoy, Chaninnun Nuntasena, Suksun Horpibulsuk, Karn Kantatham, Arul Arulrajah   +5 more
doaj   +1 more source

Infrastructure sensing [PDF]

Interface Focus, 2016
Abstract Design, construction, maintenance and upgrading of civil engineering infrastructure requires fresh thinking to minimize use of materials, energy and labour. This can only be achieved by understanding the performance of the infrastructure, both during its construction and throughout its design life, through innovative ...
Soga, Kenichi, Schooling, Jennifer
openaire   +4 more sources

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Infrastructural surveillance [PDF]

New Media & Society, 2019
This article proposes a new model of privacy: infrastructural surveillance. It departs from Agre’s classic distinction between surveillance and capture by examining the sociotechnical claims of connected and autonomous vehicles (CAVs) as requiring totalising surveillance of passengers and environment in order to operate.
Alex Gekker, Sam Hind
openaire   +3 more sources