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Reply to "Letter to Dobesh et al. on lower mortality with andexanet alfa in factor Xa inhibitor-related major bleeding". [PDF]

Res Pract Thromb Haemost
Dobesh PP, Fermann GJ, Christoph MJ, Koch B, Lesén E, Chen H, Lovelace B, Dettling T, Danese M, Ulloa J, Danese S, Coleman CI.   +11 more
europepmc   +1 more source

Co-administration of Four-Factor Prothrombin Complex Concentrate With Andexanet alfa for Reversal of Nontraumatic Intracranial Hemorrhage. [PDF]

Hosp Pharm
Pathan S.
europepmc   +1 more source

Trends and variation in andexanet alfa for the reversal of direct oral anticoagulants in NHS Trusts in England

Fisher L, Buka R, Byrne R, Black S, Curtis HJ, Wood C, Brown A, Bacon S, Croker R, Goldacre B, MacKenna B, Speed V.   +11 more
europepmc   +1 more source

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Real-world utilization of andexanet alfa

American Journal of Emergency Medicine, 2020
In 2018, the FDA approved andexanet alfa for the reversal of life-threatening hemorrhages in patients anticoagulated with apixaban or rivaroxaban. Yet, cost-effective factor Xa inhibitor reversal remains controversial. The objective of this study was to describe real world utilization of andexanet alfa.This was a retrospective case series of patients ...
Meera Sridharan, , Caitlin Brown
exaly   +5 more sources

Andexanet alfa for the reversal of factor Xa inhibitors

Expert Opinion on Biological Therapy, 2019
Andexanet alfa is a recombinant modified factor Xa protein that has been developed to reverse factor Xa inhibitors. Since May 2018, the FDA has approved its utilization in patients treated with apixaban and rivaroxaban in case of life-threatening or uncontrolled bleeding.
Michael Hardy, François Mullier, Jonathan Douxfils   +2 more
exaly   +4 more sources

Andexanet alfa

pharma-kritik, 2021
Andexanet alfa: Mit Andexanet alfa (Ondexxya®) steht ein Medikament zur Verfügung, mit dem die antikoagulierende Wirkung von Faktor-Xa-Hemmern wie z.B. Rivaroxaban (Xarelto®) aufgehoben werden kann. Ob es bei bedrohlichen Blutungen besser wirkt als eine Therapie mit Prothrombinkomplex-Konzentraten, ist noch nicht ...
openaire   +1 more source