Results 121 to 130 of about 28,940 (212)
Comprehensive androgen-dependent transcriptome analysis in human genital tissue
BMC GenomicsBackground Androgen signalling through the androgen receptor (AR) is crucial for male genital development. Disruptions in this pathway are associated with androgen insensitivity syndrome (AIS), which is typically caused by mutations in the AR gene ...
Radhika Sivaprasad +5 more
doaj +1 more source
Hypospadias as a novel feature in spinal bulbar muscle atrophy [PDF]
, 2016 Spinal and bulbar muscle atrophy (SBMA) is an X-linked neuromuscular disorder caused by CAG repeat expansions in the androgen receptor (AR) gene.
Almqvist, C. +5 more
core +1 more source
Cancer Communications, Volume 45, Issue 10, Page 1247-1284, October 2025.Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu +16 more
wiley +1 more source
Rodent Models of Polycystic Ovary Syndrome [PDF]
, 2013 Rodents are clearly valuable models for assessing disruption of fertility. The effects of different steroid treatments at different stages of reproductive life through from fetal to adult have been assessed for effects on fertility, ovarian morphology ...
Duncan, Colin, McNeilly, Alan S
core +1 more source
Androgen receptor gene mutations in 46, XY females
Journal of Research in Medical Sciences, 2006 The androgen insensitivity syndrome is a heterogeneous disorder with a wide spectrum of phenotypic abnormalities, ranging from complete female to ambiguous forms that more closely resemble males.
Mir Davood Omrani, Soraya Saleh Gargari
doaj
Not Judging by Appearances: The Role of Genotype in Jewish Law on Intersex Conditions [PDF]
, 2012 Jewish communities have always had children with intersex conditions, which involve atypical anatomic, chromosomal, or gonadal sex. In the last several decades, Orthodox rabbis have issued ad hoc rulings to assign sex to children and adults with intersex
Hillel Gray
core +1 more source
The role of hypothalamus-pituitary-adrenal (HPA)-like axis in inflammatory pilosebaceous disorders [PDF]
, 2020 Skin is the largest peripheral endocrine organ and functions as a hormone target and endocrine gland. A cutaneous hypothalamus-pituitary-adrenal (HPA)-like axis enables the skin to respond to stress and regulates its steroidogenic activity.
Clark, Ashley K +3 more
core
Complete Androgen Insensitivity Syndrome in Three Sisters [PDF]
International Journal of Fertility and Sterility, 2014 Disorders of sexual development (DSD) are congenital anomalies due to atypical development of chromosomes, gonads and anatomy. Complete androgen insensitivity syndrome (CAIS), also known as testicular feminization (TF) is a rare DSD disease. The majority
Levent Verim
doaj
European Journal of Endocrinology, 2019 OBJECTIVES To assess bone health in adult women with complete androgen insensitivity syndrome (CAIS) and removed gonads compared with age-matched healthy controls.
Giulia Gava +6 more
semanticscholar +1 more source
No Evidence that 2D:4D is Related to the Number of CAG Repeats in the Androgen Receptor Gene [PDF]
, 2013 The length ratio of the second to the fourth digit (2D:4D) is a putative marker of prenatal testosterone (T) effects. The number of CAG repeats (CAGn) in the AR gene is negatively correlated with T sensitivity in vitro. Results regarding the relationship
Honekopp, Johannes
core +2 more sources