ABSTRACT Cisplatin resistance remains a major obstacle in the treatment of gastric cancer (GC), and autophagy has been increasingly recognized as a key cytoprotective mechanism contributing to chemoresistance. CREB3L4 is an endoplasmic reticulum membrane‐bound transcription factor that has been shown to regulate the expression of Bcl‐2 associated ...
Wen‐Ke Yin +3 more
wiley +1 more source
The Relationship Between 2D:4D Digit Ratio and Polycystic Ovary Syndrome: A Systematic Review. [PDF]
Güner Emül T, Kaplan Serin E.
europepmc +1 more source
Peri‐ and Post‐Menopausal Hormone Replacement Therapy and Voice Disorder Risk: A TriNetX Study
ABSTRACT Objectives The aim of this study was to elucidate the risk of developing voice disorders among peri‐ and post‐menopausal female hormone replacement therapy (HRT) users. Methods A retrospective cohort study was conducted using the TriNetX Global Collaborative Network.
David Kayekjian +4 more
wiley +1 more source
DKK3-CKAP4 signaling drives fibroimmune remodeling and hair follicle miniaturization in androgenetic alopecia. [PDF]
An S +7 more
europepmc +1 more source
Residual and recurrent disease in advanced juvenile nasopharyngeal angiofibromas (JNAs) demonstrate spontaneous involution, reduction in size, or long‐term stability following initial treatment in 95% of patients. In this systematic review of 131 patients with advanced JNA, only 2% of patients demonstrated disease progression during surveillance, but ...
Shivani Angelique Kumar +2 more
wiley +1 more source
Androgen promotes oocyte development by upregulating gap junction intercellular communication activity in granulosa cells in mice. [PDF]
Zhang Y +5 more
europepmc +1 more source
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz +2 more
wiley +1 more source
Genetic Characterization and Multidisciplinary Management of Complete Androgen Insensitivity Syndrome: Unveiling a Novel AR Mutation. [PDF]
Francesca AM +10 more
europepmc +1 more source
Hsp90 Inhibition on the Western Blot: N‐Terminal Versus C‐Terminal Inhibitors in Breast Cancer
ABSTRACT Heat shock protein 90 (Hsp90) is an established and clinically validated anticancer target. By regulating the folding and maturation of diverse client proteins, it is indirectly involved in carcinogenesis. Key breast cancer oncogenic drivers, including estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2, are ...
Jaka Dernovšek +3 more
wiley +1 more source
Basal androgen status as a modifiable predictor of poor ovarian response in controlled ovarian hyperstimulation. [PDF]
Münch ML +9 more
europepmc +1 more source

