Results 151 to 160 of about 247,609 (252)

Toxic Effects of Bisphenol A and Its Analogs on Ovarian Structure and Function: A Narrative Review of Ovary‐Focused Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) is a widely used industrial chemical found in polycarbonate plastics and epoxy resins and is recognized for its endocrine‐disrupting properties. Human exposure is common due to its presence in food packaging and everyday products. As BPA use has been restricted, structurally similar compounds such as BPS, BPB, BPAF, and BADGE
Nurbanu Zengin, Marwa Tawfıq Ahmed Alsalım, Muhammed Canik, Sevda Bağdatlı, Nazan Deniz Yön   +4 more
wiley   +1 more source

Distinct Prognostic Roles of Grade Group and Intraductal Carcinoma of the Prostate in Metastatic Hormone-Sensitive Prostate Cancer Treated With Androgen Receptor Signaling Inhibitors. [PDF]

Int J Urol
Ikeda J, Taniguchi H, Inoue M, Masuo Y, Nakamoto T, Taguchi M, Shimada S, Mishima T, Yanishi M, Uchida K, Kinoshita H.   +10 more
europepmc   +1 more source

Low‐Dose Chlorothalonil Induces Testicular Injury Through Disruption of Steroidogenic Signaling in Adult Male Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Chlorothalonil (CHL) is a widely used organochlorine fungicide frequently detected in environmental and food matrices. Although increasing evidence indicates adverse effects in nontarget species, the mechanisms underlying CHL‐induced male reproductive toxicity remain incompletely understood.
Cristiana Livramento Oliveira Pinto, Nicoly Caixêta Gonçalves, Paula Rafaela Queiroz da Silva, Ludmila Rodrigues Pontes, Juliana Reis Machado, Virmondes Rodrigues Jr., Hugo Felix Perini, Gláucia Eloisa Munhoz de Lion Siervo   +7 more
wiley   +1 more source

Immunohistochemical Characterization of the Androgen Receptor in Breast Cancer and Its Relationship with Breast Cancer Subtypes. [PDF]

Med Sci (Basel)
Sánchez-Ferrer ML, Esteban Pedreño A, Gonzalo-Arense JJ, Ruiz Boluda I, Sarriá ML, Alonso Romero JL, Martínez DS, Martínez-Cáceres CM, Mendiola J, Torres Cantero AM.   +9 more
europepmc   +1 more source

Potential Neuroendocrine Disruption by Benzodiazepines and Its Impact on Male Fertility

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neuroactive substances have emerged as potent endocrine disruptors affecting male reproductive health through central and peripheral mechanisms. Among these, benzodiazepines, which are widely used for the management of anxiety, insomnia, epilepsy, and neuromuscular disorders, are known as GABA A (gamma‐aminobutyric acid type A) receptor ...
Ana Clara Melo Andrade de Rodrigues, Julia Gonçalves Rodrigues, Marcos de Lucca Moreira Gomes, Fernanda Carolina Ribeiro Dias   +3 more
wiley   +1 more source

Bisphenol M Induces Dose‐Dependent Hepatic Injury and Fibrotic Remodeling in Female Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The safety of bisphenol analogs as alternatives to bisphenol A (BPA) is increasingly concerning. This study investigated the hepatotoxic effects of bisphenol M (BPM), a widely used BPA substitute, in 6‐week‐old female BALB/c mice exposed to 2.5, 5, and 10 mg/kg/day intraperitoneally for 14 days. Hepatic changes were assessed via histopathology,
Muhammed Canik, Asuman Deveci Ozkan, Tuğba Kotil, Nazan Deniz Yön   +3 more
wiley   +1 more source

Anti-Androgenic Potential of Plant Extracts: Molecular Mechanisms, Synergistic Effects, and Nutritional Interventions. [PDF]

Molecules
Yang Y, Pang Y, Zhang J, Ren L.
europepmc   +1 more source

Analysis of Notch1 and Notch3 Signaling Pathway Components in Benign Prostatic Hyperplasia and Prostate Cancer Patients

Journal of Clinical Laboratory Analysis, EarlyView.
This study evaluates the association between Notch1 and Notch3 genetic variations and serum protein levels in patients with benign prostatic hyperplasia and prostate cancer. While genetic variations showed no significant link to disease risk, serum protein levels were significantly lower in prostate cancer and metastatic groups compared to healthy ...
Emine Yagci, Cansu Ozbayer, Ata Ozen, Gamze Zengin, Hulyam Kurt   +4 more
wiley   +1 more source

From <i>male PCOS</i> to male endocrine-metabolic syndrome: a gender-neutral hypothesis. [PDF]

Front Endocrinol (Lausanne)
Nordio M, Barbaro D, Pavacci V.
europepmc   +1 more source

Establishment Reference Intervals Using the Kosmic Algorithm for Hemoglobin Levels and Platelet, Red Blood Cell, and White Blood Cell Counts

Journal of Clinical Laboratory Analysis, EarlyView.
Using kosmic algorithm and SDR analysis of real‐world data from 4795 adults in Xinjiang, we established population‐specific CBC reference intervals requiring sex stratification for RBC/HGB, ethnicity stratification for PLT, and no stratification for WBC.
Chunyan Liu, Zhaohui Deng, Yingbo Song, Wenli Wu, Yan Li, Fang Yang, Huimin Liu, Xin Zhang   +7 more
wiley   +1 more source