Results 171 to 180 of about 247,609 (252)

Effective Control of Synchronous Male Breast and Prostate Cancer with Androgen Deprivation Therapy: A Case Report. [PDF]

Surg Case Rep
Furukawa M, Gondo N, Mitsueda R, Arimura A, Fujiki Y, Kawano J, Kanemitsu S, Teraoka M, Ohi Y, Rai Y, Sagara Y, Sagara Y, Ohno S.   +12 more
europepmc   +1 more source

Knockdown of CREB3L4 Inhibits Autophagy and Reduces Cisplatin Resistance in Gastric Cancer Cells by Downregulating BAG3

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cisplatin resistance remains a major obstacle in the treatment of gastric cancer (GC), and autophagy has been increasingly recognized as a key cytoprotective mechanism contributing to chemoresistance. CREB3L4 is an endoplasmic reticulum membrane‐bound transcription factor that has been shown to regulate the expression of Bcl‐2 associated ...
Wen‐Ke Yin, Xue‐Mei Xie, Xiao‐Yan Song, Yue Xiang   +3 more
wiley   +1 more source

Proteomic profiling reveals that DPP4 overexpression increases cell adhesion, inhibits cell migration, and restores androgen sensitivity in prostate cancer. [PDF]

Biosci Rep
Mora-Rodríguez JM, Sánchez BG, Bort A, Díaz-Yuste A, Milla A, Courraud J, Zoidakis J, Díaz-Laviada I.   +7 more
europepmc   +1 more source

Burden of Treatment-Induced Vasomotor Symptoms in Men With Prostate Cancer on Androgen-Deprivation Therapy: A Systematic Literature Review. [PDF]

Prostate Cancer
Ajmera M, Lou KJ, Ng S, Helbing M.
europepmc   +1 more source

COVID‐19 Amplifies Sex‐Specific Dopamine and Glial Responses in a Parkinson's Disease Mouse Model

Movement Disorders, EarlyView.
Abstract Background Exposure to environmental agents, including viral infections, may increase Parkinson's disease (PD) susceptibility, especially in males, but the neurodegenerative risk extent of COVID‐19 remains uncertain. Objectives We investigated the plausible link between severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and
Ifeoluwa Awogbindin, Mélanie Bourque, Marc Morissette, Marie‐Ève Hamelin, Chantal Rhéaume, Jared VanderZwaag, Antonia Landwehr, Disha Patel, Guy Boivin, Marie‐Ève Tremblay, Thérèse Di Paolo   +10 more
wiley   +1 more source

Approach to the patient: investigation of postmenopausal androgen excess.

J Clin Endocrinol Metab
Madden-Doyle L, Bowers K, Sherlock M, O'Reilly MW.   +3 more
europepmc   +1 more source

Erratum: The RNA helicase DDX17 enhances androgen receptor stability by interacting with the E3 ubiquitin ligase SPOP in prostate cancer. [PDF]

Transl Androl Urol
Editorial Office.
europepmc   +1 more source

Hsp90 Inhibition on the Western Blot: N‐Terminal Versus C‐Terminal Inhibitors in Breast Cancer

Medicinal Research Reviews, EarlyView.
ABSTRACT Heat shock protein 90 (Hsp90) is an established and clinically validated anticancer target. By regulating the folding and maturation of diverse client proteins, it is indirectly involved in carcinogenesis. Key breast cancer oncogenic drivers, including estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2, are ...
Jaka Dernovšek, Jernej Cingl, Urša Pečar Fonović, Tihomir Tomašič   +3 more
wiley   +1 more source

Multidisciplinary expert consensus on treatment intensification in metastatic androgen pathway modulation-sensitive prostate cancer: a case-based RAND/UCLA analysis. [PDF]

Drugs Context
Borque-Fernando Á, Alonso-Gordoa T, Juan-Fita MJ, Lopez Campos F, Pérez-Fentes DA, Vilaseca A, Moretones Agut C, Usán P, Maroto Rey P.   +8 more
europepmc   +1 more source

The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors

Medicinal Research Reviews, EarlyView.
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti, Camilla Tavani, Elena Somenza, Nicolas Tassone, Antonio d'Amati, Marta Turati, Roberto Ronca   +6 more
wiley   +1 more source