Results 181 to 190 of about 389,574 (340)

Artificial intelligence strategies for predicting kinase inhibitor resistance: A comprehensive review of methods, challenges, and future perspectives

Journal of Intelligent Medicine, EarlyView.
Abstract Kinase inhibitors are essential in targeted cancer therapy, yet resistance often emerges through secondary mutations, activation of compensatory signaling pathways, or drug‐efflux mechanisms. Artificial intelligence (AI) provides a workflow‐based strategy rather than a list of unrelated tools for predicting and addressing kinase‐inhibitor ...
Faris Hassan, Mohanad Ali Deifallah, Alaa Zaghloul, Rania Elgohary   +3 more
wiley   +1 more source

THE AROMATIZATION OF ANDROGENS BY PRIMARY MONOLAYER CULTURES OF FETAL RAT HYPOTHALAMUS [PDF]

, 1977
Jacob A. Canick, Dennis E. Vaccaro, Kenneth J. Ryan, Susan E. Leeman   +3 more
openalex   +1 more source

A two‐stage model for precise identification and Gleason grading of clinically significant prostate cancer: a hybrid approach

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 93-105, March 2025.
This study developed a two‐stage model using radiomics‐based multiparametric MRI and clinical indicators to help identify and grade clinically significant prostate cancer. The model showed promising levels of diagnostic accuracy and predictive performance.
Yuyan Zou, Xuechun Wang, Fen Ma, Xulun Liu, Chunyue Jiao, Zhen Kang, Jingjing Cui, Yang Zhang, Yan Xie, Lei Chen, Ronghua Tian   +10 more
wiley   +1 more source

Exploring the interplay of electron density distribution and electrostatic potential in the interaction of nilutamide and flutamide with androgen receptors using quantum crystallography. [PDF]

RSC Adv
Balasubramanian H, Poomani K, Kandasamy S, Hathwar VR, Gonnade RG.   +4 more
europepmc   +1 more source

Hepatocyte Growth Factor and Vitamin D Cooperatively Inhibit Androgen-Unresponsive Prostate Cancer Cell Lines [PDF]

, 2000
Laila Qadan
openalex   +1 more source

Effects of testosterone and high‐dose anabolic steroids on orthodontic‐induced bone remodeling and root resorption: An animal study

Journal of Periodontology, EarlyView.
Abstract Background This study investigates the impact of disruptions in testosterone levels on bone remodeling, root resorption, and periodontal ligament (PDL) during orthodontic tooth movement (OTM) in a pubertal male rat model. Methods Testosterone deficiency was induced through orchiectomy, and the anabolic‐androgenic steroid (AAS, testosterone ...
Caio Luiz Bitencourt Reis, Kelly Galisteu‐Luiz, Gabriela Leite Pedroso, Gustavo Lopes Puls, Leticia Cassaro, Bruno Boaventura Vieira, Fábio Lourenço Romano, Erika Calvano Küchler, Christian Kirschneck, Daniela Silva Barroso de Oliveira, Maria Bernadete Sasso Stuani, Mirian Aiko Nakane Matsumoto   +11 more
wiley   +1 more source

Computed Tomography Angiography-Assisted Ovarian Vein Sampling for Diagnosing an Androgen-Producing Leydig Cell Tumor: A Case Report. [PDF]

Case Rep Endocrinol
Tomotsune K, Saito D, Saitou S, Seki Y, Hayashi S, Yamashita Y, Takata M, Ohara K, Masugi Y, Saito Y, Kato K, Hosokawa T.   +11 more
europepmc   +1 more source

Developmental Profile of Plasma Androgens in Cockerels Genetically Selected for Mating Frequency [PDF]

, 1983
T. L. De Santo, H.P. Van Krey, P.B. Siegel, F.C. Gwazdauskas   +3 more
openalex   +1 more source

Selenium biofortification: integrating one health and sustainability

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Selenium (Se) biofortification in crops has emerged as a promising strategy to address global Se deficiencies and enhance both agricultural productivity and human health. Increasing the Se content of crops through biofortification improves their resilience to abiotic and biotic stresses and boosts their nutritional value.
Silvia Estarriaga‐Navarro, Nieves Goicoechea, Daniel Plano, Carmen Sanmartín   +3 more
wiley   +1 more source

Adipose-androgen crosstalk in polycystic ovary syndrome: mechanisms and therapeutic implications. [PDF]

Front Endocrinol (Lausanne)
Ni M, Lei H, Ye T, Wang Y.
europepmc   +1 more source