Results 261 to 270 of about 230,623 (311)

Oxidative stress reactivates androgen receptor signaling via USP36 to drive castration resistance in prostate cancer. [PDF]

Sci Rep
Fan C, Huang Z, Gao J, Gu Y, Wang N, Zhou B.   +5 more
europepmc   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Androgen Receptor Signaling Inhibitors in Non-Metastatic Castration-Resistant Prostate Cancer in Japan: The ARASHI Study. [PDF]

Int J Urol
Suzuki K, Khan N, Taguchi T, Hattori K, Chen G, Ghadessi M, Constantinovici N, Quintero V, Suzuki H.   +8 more
europepmc   +1 more source

Cryptorchidism: Novel genetic insights into CCDC149 mutations

Andrology, EarlyView.
Abstract Background Cryptorchidism, characterized by the failure of one or both testes to descend into the scrotum, is a common congenital condition that can lead to infertility and increased risk of testicular cancer. CCDC149, a coiled‐coil domain‐containing protein, has been implicated in various developmental processes, but its role in the male ...
Shengrong Du, Shan Xu, Lei Yang, Yan Ye, Yuhan Wu, Ziyun Xiao, Xiuqing Dong, Wenliang Yao, Hua Li   +8 more
wiley   +1 more source

Clinical significance of androgen receptor in unilateral invasive breast cancer in women. [PDF]

Eur J Med Res
Cao M, Pan D, Li Y, Pei Z, Wang R, Zhang B, Bian C, Gu Q, Qu P, Yu C, Liu H, Han Z.   +11 more
europepmc   +1 more source

Adjuvant‐induced arthritis induces epithelial proliferation and differential expression of SVS2 and SVS3 in the seminal vesicles

Andrology, EarlyView.
Abstract Background Rheumatoid arthritis (RA) is an inflammatory disease triggered by chronic and systemic activation of the immune system, with consequences for male fertility. However, the influence of RA on sexual accessory glands remains poorly investigated.
Thamires Miyako Ito Sigole, Camila Reis Santos, Isabela Fiorentino Souza Nascimento, Erick J. R. Silva, Agnaldo Bruno Chies, Maria Angélica Spadella   +5 more
wiley   +1 more source

Exploring the Androgen Receptor Binding Affinity of Azole Derivatives through Multiscale Computational and Experimental Approaches. [PDF]

Environ Sci Technol
Pathak RK, Jeong DH, Jang MJ, Lee HS, Kim JM.   +4 more
europepmc   +1 more source

Modified cytoskeletal and extracellular matrix composition in the canine testis after long‐acting gonadotropin‐releasing hormone agonist deslorelin treatment

Andrology, EarlyView.
Abstract Background Long‐acting gonadotropin‐releasing hormone (GnRH) agonists are commonly used for fertility control in male dogs. Their effect on testicular histomorphology has not been clarified. Objectives To elucidate the mechanisms underlying androgen withdrawal in response to long‐acting GnRH agonist deslorelin 4.7 mg treatment on testicular ...
Aykut Gram, Murat Abay, Duygu Yaman Gram, Narin Liman, Linda Müller, Orsolya Balogh   +5 more
wiley   +1 more source

Overexpression of androgen receptor signalling transactivator lncRNAs PRNCR1 and PCGEM1 are associated with the increased risk of PCOS. [PDF]

Sci Rep
Nabi M, Rasool SUA, Ashraf S, Andrabi SM, Amin S.   +4 more
europepmc   +1 more source