Results 291 to 300 of about 204,414 (356)

The MicroRNA miR-454 and the mediator complex component MED12 are regulators of the androgen receptor pathway in prostate cancer. [PDF]

Sci Rep
Guzman J, Hart M, Weigelt K, Neumann A, Aigner A, Andolfi C, Handle F, Rheinheimer S, Fischer U, Immel UD, Lieb V, Meese E, Culig Z, Wullich B, Taubert H, Wach S.   +15 more
europepmc   +1 more source

Effects of glucagon‐like peptide 1 receptor agonists on testicular dysfunction: A systematic review and meta‐analysis

Andrology, EarlyView.
Abstract Background Hypogonadism and infertility are two conditions that are heavily affected by overweight and obesity in the male patient. Glucagon‐like peptide 1 agonists (GLP‐1RAs) are a recently introduced class of antidiabetic drugs with powerful weight‐loss effect; this may induce an indirect positive effect on the testicular function ...
Gianmaria Salvio, Alessandro Ciarloni, Nicola Ambo, Monia Bordoni, Michele Perrone, Silvia Rossi, Giancarlo Balercia   +6 more
wiley   +1 more source

Disruption of androgen receptor-cofactor interactions by the RNA-binding protein FUS/TLS alters androgen signalling in prostate cancer

Brooke G, Culley R, Leach D, Latonen L, Rees E, Alkheilewi M, Pine A, Fioretti F, Reader C, Azadova A, Powell S, Reebye V, Waxman J, Visakorpi T, Bevan C.   +14 more
europepmc   +1 more source

Androgen receptor pathway inhibitors and drug-drug interactions in prostate cancer. [PDF]

ESMO Open
Bolek H, Yazgan SC, Yekedüz E, Kaymakcalan MD, McKay RR, Gillessen S, Ürün Y.   +6 more
europepmc   +1 more source

Impact of age at first visit on glycolipid metabolism, bone metabolism, and fertility potential in patients with Klinefelter syndrome

Andrology, EarlyView.
Abstract Background Classic Klinefelter syndrome (KS) is characterized by one extra X chromosome (47, XXY), leading to hypergonadotropic hypogonadism and higher risk of alterations in glycolipid homeostasis, cardiovascular diseases, and low bone mineral density. Most frequently, KS is diagnosed in adulthood because of infertility.
Giordana Ferraioli, Andrea Graziani, Noemi Sagone, Andrea Di Nisio, Massimo Iafrate, Fabrizio Dal Moro, Alberto Ferlin, Andrea Garolla   +7 more
wiley   +1 more source

Unveiling the critical role of androgen receptor signaling in avian sexual development. [PDF]

Nat Commun
Lengyel K, Rudra M, Berghof TVL, Leitão A, Frankl-Vilches C, Dittrich F, Duda D, Klinger R, Schleibinger S, Sid H, Trost L, Vikkula H, Schusser B, Gahr M.   +13 more
europepmc   +1 more source

The aporetic dialogues of Modena on gender differences: Is it all about testosterone? Episode II: Empathy

Andrology, EarlyView.
Abstract The exploration of gender differences in non‐andrological fields was the core focus of a series of discussions, which took place at the Endocrinology Unit in Modena, Italy in the form of the aporetic dialogue of ancient Greece. This second episode reports the transcript of the actual debate on testosterone's role in defining empathic behavior ...
Giulia Brigante, Clara Lazzaretti, Ali Ahmad, Massimiliano Colzani, Filippo Vignali, Michele Zoli, Manuela Simoni   +6 more
wiley   +1 more source

C/EBPβ increases tumor aggressiveness by enhancing KIFC1 expression in androgen receptor negative triple negative breast cancer. [PDF]

Cell Commun Signal
Joshi S, Garlapati C, Nguyen T, Sharma S, Chandrashekar DS, Bhattarai S, Varambally S, Krishnamurti U, Li X, Aneja R.   +9 more
europepmc   +1 more source

Fetal exposure to a mixture of endocrine‐disrupting chemicals and biomarkers of male fecundity: A population‐based cohort study

Andrology, EarlyView.
Abstract Background Fetal exposure to endocrine‐disrupting chemicals (EDCs) has been associated with reduced male fecundity, but with few studies considering chemical mixtures. Objectives We assessed the association between fetal exposure to a mixture of EDCs and biomarkers of male fecundity in young adulthood.
Sidsel Dan Hull, Karin Sørig Hougaard, Gunnar Toft, Kajsa Kirstine Ugelvig Petersen, Esben Meulengracht Flachs, Christian Lindh, Cecilia Høst Ramlau‐Hansen, Lauren A. Wise, Allen Wilcox, Zeyan Liew, Jens Peter Bonde, Sandra Søgaard Tøttenborg   +11 more
wiley   +1 more source