Results 301 to 310 of about 231,777 (344)

Androgen Receptor Formation in Prenatally Endocrine Disrupted Mice

, 2013
Conor D. Irwin
openalex   +1 more source

ZBTB7B modulates the androgen receptor as an upstream regulator via colocalization and direct binding in LNCaP prostate cancer cells. [PDF]

Transl Cancer Res
Im E, Park SY, Sim DY, Cho AR, Kil BJ, Kim B, Shim BS, Kim SH.   +7 more
europepmc   +1 more source

The Androgen Receptor and MYC synergise to modulate the synthesis of Siglec-7 ligands in prostate cancer

Duxfield A, Garnham R, Hutton E, Dowle A, Wills J, Luzzi S, Nelson R, Lishman-Walker E, Magee R, Buskin A, Hepburn AC, Tekoglu E, Maloney-Friar K, Frame F, Maitland N, Hedley A, Henderson H, McCullough B, Gowardhan B, Sahadevan K, McCracken S, Gaughan L, Heer R, Robson CN, Coffey K, Lack N, Signoret N, Fascione M, Scott E.   +28 more
europepmc   +1 more source

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The androgen receptor

2023
The Androgen Receptor (AR) is a ligand (androgen) activated transcription factor and a member of the nuclear receptor (NR) superfamily. It is required for male sex hormone function. AR-FL (full-length) has the domain structure of NRs, an N-terminal domain (NTD) required for transactivation, a DNA-binding domain (DBD), a nuclear localization signal (NLS)
Greg, Van-Duyne, Ian A, Blair, Cynthia, Sprenger, Vera, Moiseenkova-Bell, Stephen, Plymate, Trevor M, Penning   +5 more
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Androgens, Antiandrogens and Androgen Receptor Abnormalities

European Urology, 1996
Information on the molecular structure of the human androgen receptor has increased insight into the molecular mechanism of action of androgens and antiandrogens. It has also facilitated the study of molecular defects in the androgen receptor gene associated with prostate cancer.
C W, Kuil, A O, Brinkmann
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ANDROGEN RECEPTORS

Clinics in endocrinology and metabolism, 1983
Testosterone and its active metabolite dihydrotestosterone exert their influence on target cells through a specific intracellular protein receptor. Structural abnormalities of this receptor lead to a diminished androgen action within the cell and result in the syndrome of androgen insensitivity.
James S. Norris, Roy G. Smith
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Androgen Receptor Dependence

2019
Androgens and the androgen receptor (AR) play crucial roles in the biology of normal and diseased prostate tissue, including prostate cancer (PCa). This dependence is evidenced by the use of androgen depletion therapy (ADT) as the primary treatment for locally advanced, metastatic, or relapsed PCa.
Aashi P, Chaturvedi, Scott M, Dehm
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Androgen receptor mutations and androgen insensitivity

Molecular and Cellular Endocrinology, 2002
The androgen receptor (AR) is a high affinity receptor protein encoded on the human X-chromosome that mediates the actions of androgens during development and in the adult. Defects in this receptor protein result in a wide range of abnormalities of male sexual development.
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