Results 131 to 140 of about 238,876 (343)

Postnatal determinants of testicular germ cell tumor by histological subtypes: The EPSAM1 and EPSAM2 studies

open access: yesInternational Journal of Cancer, EarlyView.
What's New? While several nongenetic risk factors are linked to testicular germ‐cell tumors (TGCTs), the influence of environmental and hormonal factors remains unclear. This study evaluated the role of postnatal exposures in the etiology of TGCT using data from the ongoing EPSAM case–control investigation in Italy.
Mauro Cioffi   +10 more
wiley   +1 more source

The role of cytokines in ovarian cancer drug resistance

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Ovarian cancer is the leading cause of death among women diagnosed with female reproductive system cancers. While significant advances have been made in treating various types of cancer, progress in ovarian cancer treatment over the past 20 years has been minimal, and the treatment course of ovarian cancer is not linear. Although many patients
Lu Wang   +7 more
wiley   +1 more source

Arrhythmic expression signatures of circadian clock‐associated transcription factors and chronic circadian disruption contribute to advanced prostate cancer growth

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Circadian rhythm disruption potentially fuels prostate cancer progression. The mechanisms and signaling molecules contributing to hormonal tumorigenesis, however, remain largely undefined. In this study, circadian expression patterns of core‐circadian controlled genes (CCCGs) and nuclear receptors (NRs) were investigated in advanced ...
Ria Chopra   +4 more
wiley   +1 more source

Regulation of pyruvate dehydrogenase complex: Dancing to different drums in cancer

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Mechanisms governing the regulation of pyruvate dehydrogenase complex (PDC) are markedly modified in cancer cells compared to normal cells. PDC activity in normal cells is controlled by the reversible phosphorylation of three serine residues by dedicated kinases and phosphatases.
Mulchand S. Patel, Todd C. Rideout
wiley   +1 more source

Elevating and empowering reproductive futures: Pediatric and adolescent gynecology's specialized care across the globe

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Pediatric and adolescent gynecology (PAG) is an expanding subspecialty of obstetrics and gynecology that addresses the reproductive health needs of girls and young women worldwide. In regions with limited subspecialist healthcare providers, general obstetricians, gynecologists, and nurse‐midwives, frontline healthcare providers provide ...
Nichole A. Tyson   +6 more
wiley   +1 more source

Gynecologic surgery for benign disease: Preserving reproductive potential

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Preserving fertility is essential when managing benign gynecologic disorders in reproductive‐aged women. Surgical interventions can impact future fertility, therefore requiring an evidence‐based, individualized approach. The FIGO Committee on Reproductive Endocrinology and Infertility reviewed current literature to develop recommendations for ...
Togas Tulandi   +23 more
wiley   +1 more source

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