Results 121 to 130 of about 141,437 (356)

Androgen receptor monomers and dimers regulate opposing biological processes in prostate cancer cells

open access: yesNature Communications
Most prostate cancers express the androgen receptor (AR), and tumor growth and progression are facilitated by exceptionally low levels of systemic or intratumorally produced androgens.
Rachid Safi   +24 more
doaj   +1 more source

The “costly son” hypothesis: Sons exacerbate obstetrical dilemmas in humans and other mammals

open access: yesThe Anatomical Record, EarlyView.
Abstract Human childbirth has often been considered uniquely difficult among mammals, yet recent evidence suggests that obstructed labor and fetopelvic disproportion are widespread across placental mammals. Here, we propose the “costly son” hypothesis: because male offspring are typically larger at birth, they impose greater obstetric risk on mothers ...
Nicole D. S. Grunstra   +1 more
wiley   +1 more source

Androgens and the androgen receptor (AR)

open access: yes, 2013
Introduction Androgens are sex steroid hormones that are produced in both males and females, albeit in different amounts. Androgens are essential for development and maintenance of the male phenotype (1), and are also important in females, where they can either act directly via the androgen receptor (AR) or indirectly as metabolic precursors for ...
Moore, N.   +4 more
openaire   +2 more sources

Hormonal control and signaling of the testis of the bat Molossus molossus during the processes of testicular maturation, regression, and recrudescence

open access: yesThe Anatomical Record, EarlyView.
Abstract Molossus molossus, a species of neotropical bat belonging to the Molossidae family, has an annual reproductive cycle that includes two peaks of spermatogenic activity, one in April and another in September, and a period of total testicular regression in December.
Emília M. Soares   +6 more
wiley   +1 more source

Histological Characterization and Comparative Transcriptomic Analysis of Gonads During Early Sex Differentiation in the Northern Snakehead (Channa argus)

open access: yesAnimal Research and One Health, EarlyView.
This study delineates the early sex differentiation timeline in the northern snakehead (Channa argus). These findings provide a foundation for future sex‐control breeding in this economically important species. ABSTRACT The northern snakehead (Channa argus) is an economically important aquaculture species in China.
Chaonan Sun   +6 more
wiley   +1 more source

Follicle Stimulating Hormone in Cattle Breeding: Fundamentals, Innovations, and Scope

open access: yesAnimal Research and One Health, EarlyView.
FSH is crucial in cattle reproduction, with exogenous administration enhancing breeding and embryo production. Recombinant FSH offers advantages over pituitary‐extracted variants, including fewer injections, reduced stress, and safer production. These innovations improve breeding efficiency, optimize reproductive outcomes, and contribute to sustainable
Muhammad Shahzad   +7 more
wiley   +1 more source

Yolk Androgens and Development in American Kestrel Nestlings [PDF]

open access: yes, 2009
Maternally derived yolk androgens affect many aspects of phenotypic development. To explore this phenomenon I injected clutches of American kestrels (Falco sparverius) with one of three different dosages of testosterone + androstenedione or with vehicle.
Berg, Melanie Dawn
core  

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

open access: yesAnimal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen   +2 more
wiley   +1 more source

Investigating the role of androgens in myometrial biology during pregnancy [PDF]

open access: yes, 2015
Understanding the physiology of pregnancy enables effective management of pregnancy complications that could otherwise be life threatening for both mother and fetus.
Makieva, Sofia
core  

Effects of Androgens on the Activity of Steroid-metabolizing Enzymes in the Murine Submaxillary Gland

open access: yes, 1983
Effects of androgens on the activity of androgen-metabolizing enzymes have been investigated in the murine submaxillary gland. 5α-reductase activity is androgen-dependent, and 17β-hydroxysteroid dehydrogenase activity is androgen-resistant.
Y. Tanabe, H. Katsukawa, M. Funakoshi
core   +1 more source

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