Results 131 to 140 of about 141,437 (356)

The Nuclear Receptor Testicular Receptor 4 Orchestrates Cytoskeletal Organization in a G Protein Subunit Alpha 12/Rho‐Associated Protein Kinase–Dependent Manner to Promote Myofibroblast Differentiation and Tissue Fibrosis in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Members of the superfamily of nuclear receptors have been implicated in inflammatory processes and pathologic tissue remodeling and have emerged as attractive targets for pharmaceutical intervention. However, the role of testicular receptor 4 (TR4; or Nr2c2) in fibroblast activation and rheumatologic diseases has not yet been investigated ...
Yun Zhang, Lichong Shen, Junhui Zheng, Gisela Baur, Dilidaer Yasen, Honglin Zhu, Yi‐Nan Li, Xianyi Meng, Thuong Trinh‐Minh, Tim Filla, Debomita Chakraborty, Andrea‐Hermina Györfi, Christina Bergmann, Adam Reich, Alexander Kreuter, Georg Schett, Jörg H. W. Distler   +16 more
wiley   +1 more source

Heptyl prodigiosin from estuarine Zooshikella sp. RANM57 induces caspase-dependent apoptosis and suppresses clonogenic survival in androgen-independent prostate cancer cells [PDF]

Royston Madtha, Kedeke Balakrishna, KhansabRazak Deen, Selvam Rithick, Savarimuthu Ignacimuthu S.J., P. Pandikumar, Sreejesh Pilakkavil Chirakkara, Asha Abraham   +7 more
openalex   +1 more source

Design of azine antioxidants for sustainable biodiesel: integrating structural characterization and molecular modeling

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract The growing global demand for sustainable energy solutions has intensified the search for renewable alternatives to fossil fuels, with biodiesel emerging as a promising candidate due to its biodegradability and lower emissions. However, its large‐scale application is limited by low oxidative stability, which compromises storage and performance.
Patricia R. S. Wenceslau, Chris H. J. Franco, Leonardo R. de Almeida, Vitor S. Duarte, Ronaldo G. F. Junior, Guilherme Paixão, Antônio S. N. Aguiar, Gilberto L. B. de Aquino, Leonardo G. Costa, Leonardo L. Borges, Hamilton B. Napolitano   +10 more
wiley   +1 more source

Targeting IL-1R1 and androgen receptor using natural compounds from Aconitum heterophyllum and Podophyllum hexandrum: an in silico and in vitro study [PDF]

Mir Muskan Un Nisa, P. A. Sofi, Peerzada Ishtiyak Ahmad, Rashid Mir, Talib Bashir Bhat   +4 more
openalex   +1 more source

Localized Prostate Cancer Therapy: Tumor Microenvironment‐Activated Spermine Hydrogel With Real‐Time Autonomous Fluorescence Sensing

Chemistry – A European Journal, EarlyView.
First tumor microenvironment (TME)‐responsive spermine‐loaded hydrogel with autonomous sensing for advanced local therapy of prostate cancer (PCa) is developed. Spermine can be released from the hydrogel to kill the prostate cancer cells specifically under acidic TME.
Ho‐Fai Chau, Wing‐Sze Tam, Gengguo Deng, Yik Hoi Yeung, Christine Yim Ping Wong, Ka Lo Cheng, Zhengxiao Liu, Lijia Yao, Yi Wang, Angelo H. All, Chi‐Fai Ng, Jinming Di, Ka‐Leung Wong   +12 more
wiley   +1 more source

The improvement effect of androgen priming on fertility in patients with diminished ovarian reserve and its impact on in vitro fertilization outcomes: a systematic review and meta-analysis [PDF]

Xuanling Li, Chen-Lin Sui, Baofang Zhang, 白宇泉, Qian Zhao, Lianwei Xu   +5 more
openalex   +1 more source

The effects of androgens on steroidogenesis in the ovary of Atlantic croaker (Micropogonias undulatus) : mechanism of action, the biochemical characterization of a membrane androgen receptor, and the chronic effects of exposure to an environmental antiandrogen

, 2002
textThis study focuses on the actions of androgens in the gonads of the Atlantic croaker (Micropogonias undulatus). Physiologically relevant concentrations of androgens are shown to inhibit in vitro ovarian production of estradiol through a rapid ...
Braun, Alyssa Maria, 1974-
core  

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

Cytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith, Lauren A. Tauer, Randall H. Friedline, Xiaodi Hu, Duy Tran, Yangyi E. Luo, Nacima Hadjout‐Rabi, Elisabeth R. Barton, Jason K. Kim, Elizabeth J. Luna   +9 more
wiley   +1 more source

Androgens exert direct neuroprotective effects on the brain: A review of pre-clinical evidences

, 2010
Objective: To review available data describing pathways directly modulated by androgens that underlie brain neuroprotection. Material and methods: A literature search was performed in July 2010 using the commercially available Medline online engine ...
Fusco F, Chiancone F, Riccio R, Creta M
core  

Androgens and androgen receptor in different ploidy Cobitis loaches

, 2015
The diploid-polyploid Cobitis populations in Poland are dominated by gynogenetic allotriploid females coexisting with the low number of individuals of parental species, spined loach C. taenia and danubian loach C.
Anna Leska, Anna Pecio, Beata Cejko
core   +1 more source