Results 141 to 150 of about 141,437 (356)
Drug Testing and Analysis, EarlyView.Supercritical fluid chromatography was employed in the sample preparation for IRMS determinations in sports drug testing for the first time and the developed method was successfully validated. Cholesterol (CHOL) was introduced as a novel endogenous reference compound and population‐based Δ‐values were established as shown here.
Thomas Piper, Jana Drewes, Mario Thevis
wiley +1 more source
Endocrinology of Hirsutism: From Androgens to Androgen Excess Disorders
, 2019 Unwanted sexual hair growth has a considerable negative impact on a woman's self-esteem and quality of life. Excessive growth of terminal hair in women in a man-like pattern is defined as hirsutism and affects up to 1 in 7 women.
Bulent Okan Yildiz +3 more
core +1 more source
Drug Testing and Analysis, EarlyView.This method enables simultaneous carbon isotope confirmation of 6‐oxo‐androstenedione and testosterone markers from a single urine aliquot, using bench‐top extraction, two preparative HPLC steps with intermediate acetylation, and GC/C/IRMS analysis. It was fully validated according to WADA requirements, and real samples demonstrated its fitness for ...
Fábio Azamor de Oliveira +7 more
wiley +1 more source
The mechanisms of the anabolic actions of androgens in bone.
Androgens (male sex hormones) are one of the few agents that increase bone formation. Androgens act by binding to a specific protein, the androgen receptor (AR). To understand exactly how androgens increase bone formation, we will study mice in which the
core
Drug Testing and Analysis, EarlyView.Short‐term codeine administration (1–3 days) caused individual alterations in Athlete Biological Passport steroid markers, including elevated urinary T/E ratios and decreased serum testosterone concentrations below individual thresholds, despite no significant changes at the group level.
Alexander Andersson +5 more
wiley +1 more source
Impact of Demographic and Socioeconomic Factors on Survival Associated With Androgen Receptor Pathway Inhibitor Use in Metastatic Prostate Cancer: An Analysis of the Surveillance, Epidemiology, and End Results (SEER)-Medicare Database [PDF]
Samina Hirani +5 more
openalex +1 more source
Role of androgens in polycystic ovary syndrome
Polycystic ovary syndrome (PCOS) affects 5-10% of women worldwide, yet its origins remain unknown. Androgens are implicated in the development of PCOS, but the decisive, invasive studies needed to confirm and elucidate their roles are not feasible in ...
core
Androgens: New effects on proteoglycan biosynthesis and its consequences for atherosclerosis
, 2005 The pro- and antiatherogenic role of sex hormones is very controversial. These hormones have metabolic actions, but may also display actions directly on cells of the vasculature involved in atherosclerosis. We recently examined the effect of the male sex
Krishnankutty Sudhir (20021052) +3 more
core
ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia +2 more
wiley +1 more source
Environmental Toxicology and Chemistry, EarlyView.Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz +9 more
wiley +1 more source