Abstract Sexual differentiation in the equine fetus involves coordinated morphogenetic processes that shape both the gonads and the genital ducts. Although the formation of testes and ovaries has been relatively well documented, the temporal dynamics and morphometric patterns of the mesonephric (Wolffian) and paramesonephric (Müllerian) ducts remain ...
Tais Harumi de Castro Sasahara +4 more
wiley +1 more source
Effect of enzalutamide on anticoagulant therapy with edoxaban in patients with prostate cancer
Aims Treatment with enzalutamide in prostate cancer is challenging due to its high potential for drug–drug interactions, particularly in the typically older population of patients with frequent comorbidities treated with multiple drugs, such as anticoagulants.
Catharina J. P. Op 't Hoog +8 more
wiley +1 more source
Bovine liver slices combined with an androgen transcriptional activation assay: an in-vitro model to study the metabolism and bioactivity of steroids [PDF]
Si Wang +5 more
openalex +1 more source
Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan +8 more
wiley +1 more source
A Phase III Randomized Trial Comparing Adjuvant versus Early Salvage Radiotherapy, Both Combined with Short-term Androgen Deprivation Therapy, following a Radical Prostatectomy: Initial Results of the GETUG-AFU 17 Study [NCT00667069] [PDF]
Paul Sargos +16 more
openalex +1 more source
Mapping molluscan endocrinology: a systematic and critical appraisal
ABSTRACT Historically, a vertebrate‐centric paradigm has framed our interpretation of molluscan endocrinology, with considerable research focusing on vertebrate‐type steroid hormones (e.g. oestrogens, testosterone). However, contradictory evidence on the occurrence of vertebrate‐type steroid hormones in molluscan tissues, and a lack of the specific ...
Konstantinos Panagiotidis +3 more
wiley +1 more source
Functional mapping of androgen receptor enhancer activity [PDF]
Chia-Chi Flora Huang +23 more
openalex +1 more source
An Investigation of Hyperostosis Frontalis Interna in a Modern Anatomical Body Donor Population
ABSTRACT This research sought to examine the prevalence and severity of hyperostosis frontalis interna (HFI) in the Chicagoland anatomical body donor population. The study further aimed to elucidate potential demographic risk factors for HFI, including sex, age at death, and structural vulnerability index (SVI), as well as any common comorbidities, as ...
Amy C. Beresheim, Amanda Hall
wiley +1 more source
Well‐characterized, chemically synthesized molecules related to LGD‐4033 metabolism were used as analytical standards for the analysis of LGD‐4033 post‐administration urine samples. This approach offered further insights into LGD‐4033 metabolism, providing solid experimental proof for the structure of important previously reported metabolites and ...
Yiannis S. Angelis +5 more
wiley +1 more source
ABSTRACT Objective Binge eating disorder (BED) is maintained by increased food‐related incentive salience, which is reflected by an attentional bias for food. Oxytocin acutely attenuates this bias in patients with anorexia nervosa and reduces food intake in males with normal or increased body weight.
Julia Nannt +6 more
wiley +1 more source

