Results 121 to 130 of about 5,820 (221)

Andrographolide Inhibits the NF-κB Signaling Pathway and Alleviates High-Fat Diet-Induced Hepatic Inflammation in a Mouse Model of Nonalcoholic Fatty Liver Disease

Natural Product Communications
Background High-fat diet (HFD)-induced nonalcoholic fatty liver disease (NAFLD) is a key link between several medical conditions and is becoming a major health concern affecting thousands of people globally.
Weiwen Hu, Yilin Chen, Wenhong Tan, Yirong Wang, Die Huang, Hao Yuan   +5 more
doaj   +1 more source

The Effects of A Natural Product Andrographolide in Cancer Cells

, 2017
天然藥物源於自然界中存在有藥理活性的天然產物。多種從中草藥萃取出的天然藥物都有抗發炎或抗癌的功效；且大部分的天然物帶有親電子性官能基，可與目標蛋白質共價修飾其親核基側鏈。天然物andrographolide萃取自爵床科穿心蓮 (Andrographis paniculata Nees)，其有廣泛性的生藥活性，如抗發炎、抗癌、抗菌等。再者研究報告指出andrographolide以中草藥萃取物或其衍生物均為安全性用藥；其在抗發炎方面功效雖被廣泛探討，然詳細藥理機制尚未明朗。NF ...
Ho, Ya-Yeh, 何雅燁
core  

Entrapment of andrographolide in cross-linked alginate pellets: II. Physicochemical characterization to study the pelletization of andrographolide.

Pakistan journal of pharmaceutical sciences, 2007
This paper deals with the characterization of pellets containing andrographolide in two parts. The first part deals with characterization of the pellets to ascertain the identity and integrity of andrographolide. Part two involves characterization of the pellets containing Andrographis paniculata extract (33.3%) prepared in the paper I for their ...
Shariff, Arshia, Manna, PK, Paranjothy, KLK, Manjula, M   +3 more
openaire   +2 more sources

Andrographolide enhanced 5-fluorouracil-induced antitumor effect in colorectal cancer via inhibition of c-MET pathway

, 2017
Meng Su,1 Baoli Qin,1 Fang Liu,2 Yuze Chen,2 Rui Zhang2 1Department of Internal Medicine, 2Department of Colorectal Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute, Liaoning, China Abstract: Colorectal ...
Su M, Chen Y, Zhang R, Qin B, Liu F
core  

Andrographolide Alleviates Liver Damage Caused by <i>Salmonella</i> in Mice by Inhibiting the PANoptosis Pathway. [PDF]

Microorganisms
Li Q, Hou L, Su L, Wang X, Zhu Y, Fang B.   +5 more
europepmc   +1 more source

Andrographolide in Sepsis: Mechanistic Basis, New Drug States, and Advanced Delivery Systems. [PDF]

Int J Gen Med
Zhu Q, Hu D, Xing J, Zhao Q.
europepmc   +1 more source

Andrographolide Suppresses Influenza A Virus-Induced Pyroptosis via PI3K/AKT-Mediated Caspase-3/GSDME Inactivation. [PDF]

Biomedicines
Yang W, He Q, Sun Z, Zhang X, Li Q, Zhou C, Cui Y, Wei Z, Shi J, Wang C, Jiao Y, Guo L, Xing Y, Wang S.   +13 more
europepmc   +1 more source

Comprehensively investigating pharmacokinetics and metabolic fate of andrographolide in rats by liquid chromatography/mass spectrometry-based approach. [PDF]

RSC Adv
Sun X, Zhang Y, Shang Z, Dou L, Wang T, Qiu J, Chen S.   +6 more
europepmc   +1 more source

Exploratory pharmacokinetic-pharmacodynamic characterization and safety of standardized <i>Andrographis paniculata</i> aqueous extract capsules in patients with mild COVID-19. [PDF]

Front Pharmacol
Songvut P, Payoong P, Okada PA, Rittapai N, Suntararuks S, Akanimanee J, Rangkadilok N, Panomvana D, Puranajoti P, Satayavivad J.   +9 more
europepmc   +1 more source

Evaluation of <i>Andrographis paniculata</i> in a mouse model of influenza A viral infection using oral administration and a translationally relevant dose. [PDF]

Front Pharmacol
Shamim K, Burnett GC, Zhang J, Ahmed NH, Khan SI, Chittiboyina AG, Khan IA, Marshall GD, Bates JT, Pugh ND.   +9 more
europepmc   +1 more source