Results 71 to 80 of about 4,348 (183)

The therapeutic potential of andrographolide in cancer treatment

Biomedicine & Pharmacotherapy
Cancer poses a substantial global health challenge, necessitating the widespread use of chemotherapy and radiotherapy. Despite these efforts, issues like resistance development and severe side effects remain. As such, the search for more effective alternatives is critical.
Jiaxuan, Hu, Yi, Li, Xin, Xie, Yunlei, Song, Wenjing, Yan, Yan, Luo, Yumao, Jiang   +6 more
openaire   +2 more sources

A Determination of andrographolide from Andrographis paniculata growing in Thua Thien Hue with high performance liquid chromatography

Tạp chí Khoa học Đại học Huế: Khoa học Tự nhiên
Andrographis paniculata (Acanthaceae) is a medicinal plant commonly used in Vietnam in the 1980s. The chemical composition of the plant includes a group of diterpene lactones with antimicrobial, cytotoxic, antidiabetic, and anti-inflammatory activities.
Phuong Ha Tran, Thi Diem Tran Phan, Canh Viet Cuong Le   +2 more
doaj   +1 more source

Establishment of Adventitious Root Cultures and Analysis of Andrographolide in

Natural Product Communications, 2013
Andrographolide is the principal bioactive component of the medicinal plant Andrographis paniculata , to which various diverse pharmacological properties are attributed.
Shiv Narayan Sharma, Zenu Jha, Rakesh Kumar Sinha   +2 more
doaj   +1 more source

Andrographolide-loaded silk fibroin nanoparticles

RSC Advances, 2018
Andrographolide (AP) is a diterpenoid separated from Andrographis paniculata with a wide spectrum of biological activities including anti-inflammatory, anticancer, hepatoprotective, and antihyperlipidemic.
Xu Zhongyu, Ren Jiangmeng, Jing Qiufang, Ren Fuzheng, Huang Mengting, Ding Wenrui, Zeng Bubing   +6 more
openaire   +3 more sources

Adaptogenic potential of andrographolide: An active principle of the king of bitters (Andrographis paniculata)

Journal of Traditional and Complementary Medicine, 2015
Andrographolide is a major bioactive secondary plant metabolite isolated Andrographis paniculata (Burm. F.) Wall. Ex. Nees. (穿心蓮 chuān xīn lián), a well-known traditionally used medicinal herb.
Ajit Kumar Thakur, Shyam Sunder Chatterjee, Vikas Kumar   +2 more
doaj   +1 more source

Strategies for formulation development of andrographolide

RSC Advances, 2016
This review is the comprehensive account of the pharmaceutical aspects of andrographolide with special emphasis on its delivery that have take place over the century.
Atmaram Pawar, S. Rajalakshmi, Piyush Mehta, Karimunnisa Shaikh, Chellampillai Bothiraja   +4 more
openaire   +1 more source

Anti-tumor effect of cisplatin in human oral squamous cell carcinoma was enhanced by andrographolide via upregulation of phospho-p53 in vitro and in vivo

Tumor Biology, 2017
Oral squamous cell carcinoma is one of the most common neoplasm in the world. Despite the improvements in diagnosis and treatment, the outcome is still poor now. Thus, the development of novel therapeuticapproaches is needed.
Songjie Chen, Hui Hu, Shushu Miao, Jiayong Zheng, Zhijian Xie, Hui Zhao   +5 more
doaj   +1 more source

A Systematic Review on the Antimicrobial Activity of Andrographolide

Journal of Microbiology and Biotechnology
Andrographolide, a bioactive compound from Andrographis paniculata, has gained attention for its antimicrobial properties, which include antibacterial, antiviral, antifungal, and antiprotozoal effects. As an herbal extract used in traditional medicines, andrographolide also shows promise for developing new antimicrobial agents, especially in the fight ...
Dafur, Gayus Sale, Harun, Aiza, Kub, Tuan Noorkorina Tuan, Bakar, Ruzilawati Abu, Harun, Azian   +4 more
openaire   +2 more sources

Effects and Mechanisms of Andrographolide for COVID-19: A Network Pharmacology-Based and Experimentally Validated Study

Natural Product Communications
Objective: This study aimed to elucidate the therapeutic effects and underlying mechanisms of andrographolide against COVID-19 through a network pharmacology approach and experimental validation.
Jingyi Zhang, Hongmei Lu, Yongdui Ruan, Shiyi Huang, Siying Deng, Yinuo Wang, Qing Li, Zuguo Zhao, Long Feng, Wentao Guo   +9 more
doaj   +1 more source

Evaluation of the Effect of Andrographolide on the Serum Activity of Superoxide Dismutase and Catalase Enzymes and Serum Levels of Malondialdehyde in the Rats with Secondary Iron Overload

Journal of Ardabil University of Medical Sciences, 2018
Background & objectives: Andrographolide has potent antioxidant properties. There is still not a complete understanding of the antioxidant effects of andrographolide.
Farid Manafi, Reza Alipanah-Moghadam, Ali Nemati, Vadood Malekzadeh,   +4 more
doaj