Results 51 to 60 of about 5,820 (221)
EFFECT OF SOLVENT FLOW RATE ON THE SUPERCRITICAL CARBON DIOXIDE EXTRACTION OF ANDROGRAPHOLIDE FROM ANDROGRAPHIS PANICULATA [PDF]
, 2006 Malaysia is one of the major medicinal plants (Andrographis paniculata) producers in the world. Extraction of bioactive component (andrographolide) from ground dried leaves of this plant using supercritical carbon dioxide has been studied.
Kumoro, A.C., Hasan, M.
core
Asian Pacific Journal of Tropical Biomedicine, 2018 Objective: To explore the effect of gibberellic acid (GA3) and its inhibitor paclobutrazol (PBZ) on chemical composition and their pharmacological effects on Andrographis paniculata (Burm. f.) Wall. ex Nees, and to clarify action mode of andrographolide.
Netiya Karaket +5 more
doaj +1 more source
Anticancer Activity of Andrographolide Semisynthetic Derivatives [PDF]
Natural Product Communications, 2010 Andrographolide 1, a diterpene lactone of Andrographis paniculata, displays in vitro and in vivo antitumor activity against breast cancer models and mouse myeloid leukemia (M1) cells. In the present study, we report the semi-synthesis of andrographolide derivatives and their in vitro activity against A549 (ATCC) (NSCL cancer) cell ...
Vidya, Menon, Sujata, Bhat
openaire +2 more sources
Modelling of Andrographolide Extraction from Andrographis Paniculata Leaves in a Soxhlet Extractor [PDF]
, 2006 Andrographolide is the main diterpenoid lactone contained in the leaves of Andrographis paniculata. This bioactive component has multifunctional medicinal properties such as activity against fever, dysentery, diarrhoea, inflammation, and sore throat as
Kumoro, A.C. +3 more
core
Andrographolide inhibits chikungunya virus infection by up-regulating host innate immune pathways
Asian Pacific Journal of Tropical Medicine, 2018 Objective: To investigate the therapeutic efficacy of andrographolide, a plant derived compound, against chikungunya virus (CHIKV) infection. Methods: Using flow cytometry and immunoblotting assay, in vitro viral protein expression was studied in THP-1 ...
Swati Gupta +5 more
doaj +1 more source
Andrographolide enhances the anti-metastatic effect of radiation in Ras-transformed cells via suppression of ERK-mediated MMP-2 activity. [PDF]
PLoS ONE, 2018 BACKGROUND:Activation of Ras oncogene in human tumors is associated with radiation-associated metastatic potential. Although ionizing radiation is one important method of cancer treatments, it has been shown to enhance matrix metalloproteinases (MMPs ...
Chih-Chia Yu +7 more
doaj +1 more source
Molecules, 2021 Spodoptera litura Fab. is a polyphagous pest causing damage to many agriculture crops leading to yield loss. Recurrent usage of synthetic pesticides to control this pest has resulted in resistance development.
Edward-Sam Edwin +14 more
doaj +1 more source
TCM‐Guided Targeted Therapies Against NLRP3 Inflammasome in NAFLD
Immunity, Inflammation and Disease, Volume 14, Issue 6, June 2026.This graphical abstract illustrates TCM syndrome differentiation‐guided targeted strategies against NLRP3 inflammasome‐mediated non‐alcoholic fatty liver disease (NAFLD). Metabolic dysfunction and gut‐liver axis dysregulation drive NAFLD progression, activating the NLRP3 inflammasome (comprising NLRP3, ASC, caspase‐1) to trigger cytokine release (IL‐1β,
Yanxia Zhang
wiley +1 more source
SUPERCRITICAL CARBON DIOXIDE EXTRACTION OF ANDROGRAPHOLIDE FROM ANDROGRAPHIS PANICULATA LEAVES USING METHANOL AS COSOLVENT [PDF]
, 2006 The optimisation and design of any separation processes, such as the extraction of bio molecules from their natural resources require mathematical modelling.
Kumoro, A.C., Hasan, M.
core
Progress in Natural Products Target Discovery Technology
MedComm, Volume 7, Issue 6, June 2026.Here, we provide a comprehensive overview of current technologies and recent advancements in therapeutic target discovery for natural products. By systematically synthesizing the principles, methodologies, and practical applications of existing experimental and computational strategies, this work provides a more actionable reference framework for ...
Qiyuan Pan +7 more
wiley +1 more source