Results 31 to 40 of about 5,820 (221)
Frontiers in Pharmacology, 2019 Andrographolide, a bioactive phytochemical from Andrographis paniculata, is emerging as a promising anticancer agent against various cancers. This study aims to investigate anticancer activities of andrographolide against cholangiocarcinoma (CCA) and to ...
Phorutai Pearngam +3 more
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Acta Pharmaceutica Sinica B, 2016 Acute lung injury (ALI) or acute respiratory distress syndrome (ARDS) is a severe, life-threatening medical condition characterized by widespread inflammation in the lungs, and is a significant source of morbidity and mortality in the patient population.
Shuang Peng +7 more
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Natural Product Communications, 2021 Drug repurposing is commonly employed in the search for potential therapeutic agents. Andrographis paniculata , a medicinal plant commonly used for symptomatic relief of the common cold, and its phytoconstituent andrographolide, have been repeatedly ...
Xin Yi Lim +6 more
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Protective effects of andrographolide against diclofenac-induced gastric damage
Scientific African, 2021 The use diclofenac in pain management is limited by the development of gastric ulcers. Andrographolide is a clinically approved medicinal plant extract that has been found to possess among others, a gastro protective effect and may therefore be useful in
Augustine Tandoh +5 more
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, 2018 Andrographolide is a diterpene lactone compound extracted from Andrographis paniculata (Burm. F) Nees, which is commonly used as traditional Chinese medicine. Andrographolide has effects of anti-inflammatory, antibacterial, antivirus, antitumor, and immune regulation and is used in treatment of cardiovascular-cerebrovascular diseases and protection of ...
Yan, Yu, Fang, Lian-Hua, Du, Guan-Hua
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Inhibitory Activity of Andrographolide and Andrograpanin on the Rate of PGH2 Formation [PDF]
Pharmacology and Clinical Pharmacy Research, 2016 Cyclooxygenase (COX) or prostaglandin H2 synthase (PGHS) catalyzes the conversion of arachidonic acid into prostaglandins. Nonsteroidal anti-inflammatory drugs (NSAIDs) work by inhibiting both COX-1 and COX-2 isoforms, thus disturbing this reaction.
Sri A. Sumiwi +6 more
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Frontiers in Pharmacology, 2022 Females have higher inflammatory tolerance because they have some special sex-related anti-inflammatory pathways. Andrographolide, a diterpene lactone compound from Andrographis paniculata (Burm.f.) Nees, has a powerful anti-inflammatory effect.
Xiaoyan Yuan +6 more
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Andrographolide and analogues in cancer prevention
Frontiers in Bioscience, 2015 Andrographis paniculata is a medicinal plant traditionally used for treatment of cough and cold, fever, laryngitis, and several infectious diseases. Extracts of A. paniculata have shown versatile potency against various diseases including cancer. The active biomolecules of A. paniculata mainly are lactone and diterpene.
Siddhartha Kumar, Mishra +4 more
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Construction and agrochemical efficacy of novel indolo[2,3-b]andrographolide derivatives
Advanced Agrochem, 2023 To find new pesticide candidates, by using of a natural product andrographolide as the precursor, a series of novel indolo[2,3-b]andrographolide derivatives were semisynthesized by Fischer-indole rearrangement reaction.
Meng Hao, Min Lv, Tianze Li, Hui Xu
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Molecules, 2022 Reactivation of Epstein–Barr virus (EBV) is associated with EBV-associated malignancies and is considered to be a benefit target for treatment. Andrographolide is claimed to have antiviral and anti-tumor activities.
Praphatson Malat +6 more
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