Results 31 to 40 of about 4,348 (183)
Inhibitory Activity of Andrographolide and Andrograpanin on the Rate of PGH2 Formation [PDF]
Pharmacology and Clinical Pharmacy Research, 2016 Cyclooxygenase (COX) or prostaglandin H2 synthase (PGHS) catalyzes the conversion of arachidonic acid into prostaglandins. Nonsteroidal anti-inflammatory drugs (NSAIDs) work by inhibiting both COX-1 and COX-2 isoforms, thus disturbing this reaction.
Sri A. Sumiwi +6 more
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Construction and agrochemical efficacy of novel indolo[2,3-b]andrographolide derivatives
Advanced Agrochem, 2023 To find new pesticide candidates, by using of a natural product andrographolide as the precursor, a series of novel indolo[2,3-b]andrographolide derivatives were semisynthesized by Fischer-indole rearrangement reaction.
Meng Hao, Min Lv, Tianze Li, Hui Xu
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Molecules, 2022 Reactivation of Epstein–Barr virus (EBV) is associated with EBV-associated malignancies and is considered to be a benefit target for treatment. Andrographolide is claimed to have antiviral and anti-tumor activities.
Praphatson Malat +6 more
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Andrographolide and analogues in cancer prevention
Frontiers in Bioscience, 2015 Andrographis paniculata is a medicinal plant traditionally used for treatment of cough and cold, fever, laryngitis, and several infectious diseases. Extracts of A. paniculata have shown versatile potency against various diseases including cancer. The active biomolecules of A. paniculata mainly are lactone and diterpene.
Siddhartha Kumar, Mishra +4 more
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Research Progress of the Biosynthesis and Regulation of Andrographolide
Guangdong nongye kexueAndrographolide is the main active ingredient of Andrographis paniculata, which has the functions of clearing heat and detoxifying, antibacterial and anti-inflammatory, protecting liver and improving gallbladder.
Long ZHANG +6 more
doaj +1 more source
Design Considerations for Polymer–Deep Eutectic Solvent Hybrid Systems for Transdermal Drug Delivery
Journal of Applied Polymer Science, EarlyView.Deep eutectic solvents (DESs) act as tunable, green excipients that modulate polymer structure–property relationships to enhance drug solubility, skin permeation, stability, and controlled release. Through hydrogen‐bond interactions, DES–polymer hybrid systems enable improved transdermal performance, offering a rational, design‐driven platform for ...
Madhavi Kailas Kapale +3 more
wiley +1 more source
Six New Andrographolide Metabolites in Rats
Chemical and Pharmaceutical Bulletin, 2003 AbstractFor Abstract see ChemInform Abstract in Full Text.
He, Xiangjiu +5 more
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Biosensors, 2022 Andrographolide is an active diterpenoid compound extracted from Andrographis paniculata. It exhibits antiinflammatory and anticancer effects. Previous studies show that it is non-toxic to experimental animals.
Heng-Yi Liao +6 more
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Andrographolide Modulates Fibrogenic and Oxidative Stress Responses in Human Lung Fibroblasts
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Pulmonary fibrosis is a progressive lung disorder characterized by fibroblast activation and excessive extracellular matrix deposition. Andrographolide (ANDRO) has been reported to attenuate pulmonary fibrosis, but the underlying molecular mechanisms remain incompletely understood.
Yu‐Hsin Tseng +8 more
wiley +1 more source
Asian Pacific Journal of Tropical Biomedicine, 2018 Objective: To explore the effect of gibberellic acid (GA3) and its inhibitor paclobutrazol (PBZ) on chemical composition and their pharmacological effects on Andrographis paniculata (Burm. f.) Wall. ex Nees, and to clarify action mode of andrographolide.
Netiya Karaket +5 more
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