Results 21 to 30 of about 4,348 (183)

Quantification of Andrographolide Isolated from Andrographis paniculata Nees Obtained from Traditional Market in Yogyakarta Using Validated HPLC

Indonesian Journal of Chemistry, 2016
This research was aimed to quantification of andrographolide isolated from A. paniculata Ness found in traditional market in Yogyakarta using validated HPLC to obtain high level content of andrographolide.
Yandi Syukri, Ronny Martien, Endang Lukitaningsih, Agung Endro Nugroho   +3 more
doaj   +1 more source

Andrographolide Exhibits Anticancer Activity against Breast Cancer Cells (MCF-7 and MDA-MB-231 Cells) through Suppressing Cell Proliferation and Inducing Cell Apoptosis via Inactivation of ER-α Receptor and PI3K/AKT/mTOR Signaling

Molecules, 2022
Breast cancer is the most common cancer among women worldwide. Chemotherapy followed by endocrine therapy is the standard treatment strategy after surgery or radiotherapy.
Ruhainee Tohkayomatee, Somrudee Reabroi, Duangjai Tungmunnithum, Warisara Parichatikanond, Darawan Pinthong   +4 more
doaj   +1 more source

Andrographolide: A Review of Analytical Methods

Journal of Chromatographic Science, 2020
AbstractBicyclic diterpenoid lactone andrographolide is regarded as a “natural antibiotic” as it is known to exhibit a range of bioactivities including anti-inflammatory, antibacterial, antipyretic, antineoplastic, cardioprotective, hepatoprotective and hypoglycaemic, and is present in Andrographis paniculata.
Rashmi Patil, Vandana Jain
openaire   +2 more sources

Andrographolide Inhibits Cholangiocarcinoma Cell Migration by Down-Regulation of Claudin-1 via the p-38 Signaling Pathway

Frontiers in Pharmacology, 2019
Andrographolide, a bioactive phytochemical from Andrographis paniculata, is emerging as a promising anticancer agent against various cancers. This study aims to investigate anticancer activities of andrographolide against cholangiocarcinoma (CCA) and to ...
Phorutai Pearngam, Supeecha Kumkate, Seiji Okada, Tavan Janvilisri   +3 more
doaj   +1 more source

Antioxidant Activity of Andrographolide from Andrographis paniculata leaf and Its Extraction Optimization by using Accelerated Solvent Extraction

Journal of Tropical Life Science, 2023
Andrographis paniculata is widely used as a medicinal plant in many countries and andrographolide is the major bioactive compound extracted from A. paniculata leaf.
Mariani Abdul Hamid, Rabe'ah Adam, Faiqah Ramli, Roswanira Wahab   +3 more
doaj   +1 more source

(Burm. F.) Wall. Ex Nees, Andrographolide, and Andrographolide Analogues as SARS-CoV-2 Antivirals? A Rapid Review

Natural Product Communications, 2021
Drug repurposing is commonly employed in the search for potential therapeutic agents. Andrographis paniculata , a medicinal plant commonly used for symptomatic relief of the common cold, and its phytoconstituent andrographolide, have been repeatedly ...
Xin Yi Lim, Janice Sue Wen Chan, Terence Yew Chin Tan, Bee Ping Teh, Mohd Ridzuan Mohd Abd Razak, Saharuddin Mohamad, Ami Fazlin Syed Mohamed   +6 more
doaj   +1 more source

Protective effects of andrographolide against diclofenac-induced gastric damage

Scientific African, 2021
The use diclofenac in pain management is limited by the development of gastric ulcers. Andrographolide is a clinically approved medicinal plant extract that has been found to possess among others, a gastro protective effect and may therefore be useful in
Augustine Tandoh, Cynthia Amaning Danquah, Paul Poku Sampene Ossei, Charles Kwaku Benneh, William Gilbert Ayibor, Eric Woode   +5 more
doaj   +1 more source

Andrographolide sulfonate ameliorates lipopolysaccharide-induced acute lung injury in mice by down-regulating MAPK and NF-κB pathways

Acta Pharmaceutica Sinica B, 2016
Acute lung injury (ALI) or acute respiratory distress syndrome (ARDS) is a severe, life-threatening medical condition characterized by widespread inflammation in the lungs, and is a significant source of morbidity and mortality in the patient population.
Shuang Peng, Nan Hang, Wen Liu, Wenjie Guo, Chunhong Jiang, Xiaoling Yang, Qiang Xu, Yang Sun   +7 more
doaj   +1 more source

Andrographolide exerted anti-inflammatory effects thereby reducing sex hormone synthesis in LPS-induced female rats, but had no effect on hormone production in healthy ones

Frontiers in Pharmacology, 2022
Females have higher inflammatory tolerance because they have some special sex-related anti-inflammatory pathways. Andrographolide, a diterpene lactone compound from Andrographis paniculata (Burm.f.) Nees, has a powerful anti-inflammatory effect.
Xiaoyan Yuan, Wenhao Xu, Zijun Yan, Xingmeng Xu, Yanqing Chen, Simin Chen, Ping Wang   +6 more
doaj   +1 more source

Andrographolide

, 2018
Andrographolide is a diterpene lactone compound extracted from Andrographis paniculata (Burm. F) Nees, which is commonly used as traditional Chinese medicine. Andrographolide has effects of anti-inflammatory, antibacterial, antivirus, antitumor, and immune regulation and is used in treatment of cardiovascular-cerebrovascular diseases and protection of ...
Yan, Yu, Fang, Lian-Hua, Du, Guan-Hua
openaire   +1 more source