Results 1 to 10 of about 5,820 (221)

Andrographolide Inhibits Biofilm and Virulence in Listeria monocytogenes as a Quorum-Sensing Inhibitor

Molecules, 2022
Listeria monocytogenes is a major foodborne pathogen that can cause listeriosis in humans and animals. Andrographolide is known as a natural antibiotic and exhibits good antibacterial activity. We aimed to investigate the effect of andrographolide on two
Tao Yu, Xiaojie Jiang, Xiaobo Xu, Congyi Jiang, Rui Kang, Xiaobing Jiang   +5 more
doaj   +2 more sources

Pharmacokinetic interaction of saxagliptin with andrographolide and their hypoglycemic effect in type 2 diabetes rats [PDF]

Acta Poloniae Pharmaceutica, 2023
Controlling blood glucose is the primary therapeutic strategy for T2DM. Both saxagliptin and andrographolide possess hypoglycemic effects, which makes the combination easy.
Suyan Wu, Haifei Pan, Yingying Huang
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Development of a Bifunctional Andrographolide-Based Chemical Probe for Pharmacological Study. [PDF]

PLoS ONE, 2016
Andrographolide (ANDRO) is a lactone diterpenoid compound present in the medicinal plant Andrographis paniculata which is clinically applied for multiple human diseases in Asia and Europe.
Ya-Hsin Hsu, Yu-Ling Hsu, Sheng-Hung Liu, Hsin-Chia Liao, Po-Xuan Lee, Chao-Hsiung Lin, Lee-Chiang Lo, Shu-Ling Fu   +7 more
doaj   +2 more sources

Comparative efficacy of andrographolide and hordenine in the treatment of methicillin resistant Staphylococcus aureus infected wounds: a multifaceted approach [PDF]

Journal of Ayurveda and Integrative Medicine
Background: Wound healing is a multifaceted biological process hindered by infections, especially the methicillin-resistant Staphylococcus aureus (MRSA), which resists antibiotics.
S.J. Vidyavarsha, Bibu John Kariyil, Varsha Unni, R. Anoopraj   +3 more
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The inhibition of deep peritoneal endometriosis by Andrographolide through macrophage M1 activity in an endometriosis mice model [PDF]

Veterinární Medicína
This study aims to demonstrate that Andrographolide, an herbal immunostimulant, can influence M1 macrophages to inhibit inflammation, including the growth of endometriosis caused by inflammation.
IA Susianto, N Susilaningsih, ST Hidayat, Hardian, RR Tjandrawinata, B Rachmawati   +5 more
doaj   +2 more sources

Application of a Multilayer Perceptron Artificial Neural Network for the Prediction and Optimization of the Andrographolide Content in Andrographis paniculata

Molecules, 2022
Andrographolide, the principal secondary metabolite of Andrographis paniculata, displays a wide spectrum of medicinal activities. The content of andrographolide varies significantly in the species collected from different geographical regions. Therefore,
Bibhuti Bhusan Champati, Bhuban Mohan Padhiari, Asit Ray, Tarun Halder, Sudipta Jena, Ambika Sahoo, Basudeba Kar, Pradeep Kumar Kamila, Pratap Chandra Panda, Biswajit Ghosh, Sanghamitra Nayak   +10 more
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Andrographolide Induces ROS-Mediated Cytotoxicity, Lipid Peroxidation, and Compromised Cell Integrity in Saccharomyces cerevisiae

Antioxidants, 2023
Andrographolide, a bioactive compound found in Andrographis paniculata, has gained significant attention for its potential therapeutic properties. Despite its promising benefits, the understanding of its side effects and underlying mechanisms remains ...
Tanaporn Phetruen, Bloem van Dam, Sittinan Chanarat   +2 more
doaj   +1 more source

Andrographolide Inhibits Lytic Reactivation of Epstein-Barr Virus by Modulating Transcription Factors in Gastric Cancer

Microorganisms, 2021
Andrographolide is the principal bioactive chemical constituent of Andrographis paniculata and exhibits activity against several viruses, including Epstein–Barr virus (EBV).
Praphatson Malat, Tipaya Ekalaksananan, Chukkris Heawchaiyaphum, Supawadee Suebsasana, Sittiruk Roytrakul, Yodying Yingchutrakul, Chamsai Pientong   +6 more
doaj   +1 more source

Adverse Effects of Andrographolide Derivative Medications Compared to the Safe use of Herbal Preparations of Andrographis paniculata: Results of a Systematic Review and Meta-Analysis of Clinical Studies

Frontiers in Pharmacology, 2022
Background and objective:Andrographis paniculata (AP) is a traditionally used herbaceous plant, whose main active constituent is andrographolide. Andrographolide derivative medications and herbal preparations of AP are often used to treat respiratory ...
Ya-xi Shang, Chen Shen, Trine Stub, Si-jia Zhu, Shu-yu Qiao, Yu-qi Li, Rui-ting Wang, Jing Li, Jian-ping Liu   +8 more
doaj   +1 more source

Andrographolide, an Anti-Inflammatory Multitarget Drug: All Roads Lead to Cellular Metabolism

Molecules, 2020
Andrographolide is a labdane diterpene and the main active ingredient isolated from the herb Andrographis paniculata. Andrographolide possesses diverse biological effects including anti-inflammatory, antioxidant, and antineoplastic properties.
Rafael Agustín Burgos, Pablo Alarcón, John Quiroga, Carolina Manosalva, Juan Hancke   +4 more
doaj   +1 more source