Influence of andrographolide on the pharmacokinetics of warfarin in rats [PDF]
Pharmaceutical Biology, 2018 Context: Andrographolide and warfarin are often used together in clinics in China. However, the herb-drug interaction between andrographolide and warfarin is still unknown.
Xiaoli Zhang +3 more
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Lipase catalyzed synthesis of antimicrobial andrographolide derivatives
Data in Brief, 2018 In this data article we describe screening of various lipases for the regioselective acylation of Andrographolide. Each lipase was screened with seven acyl donors.
Harshal S. Patil +5 more
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Research Progress of the Biosynthesis and Regulation of Andrographolide
Guangdong nongye kexueAndrographolide is the main active ingredient of Andrographis paniculata, which has the functions of clearing heat and detoxifying, antibacterial and anti-inflammatory, protecting liver and improving gallbladder.
Long ZHANG +6 more
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Andrographolide protects against LPS-induced acute lung injury by inactivation of NF-κB. [PDF]
PLoS ONE, 2013 Nuclear factor-κB (NF-κB) is a central transcriptional factor and a pleiotropic regulator of many genes involved in acute lung injury. Andrographolide is found in the plant of Andrographis paniculata and widely used in Traditional Chinese Medicine ...
Tao Zhu +11 more
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STRUCTURE MODIFICATION OF ANDROGRAPHOLIDE TO IMPROVE ITS POTENCY AS ANTICANCER
Indonesian Journal of Chemistry, 2010 Andrographolide, a diterpenoid lactone isolated from the herb of Andrographis paniculata and known to possess antitumor activity in breast cancer models was subjected to semisynthesis leading to the preparation of a number of derivatives.
Hadi Poerwono +3 more
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Andrographolide Inhibits Corneal Fibroblast to Myofibroblast Differentiation In Vitro [PDF]
Biomolecules, 2022 Corneal opacification due to fibrosis is a leading cause of blindness worldwide. Fibrosis occurs from many causes including trauma, photorefractive surgery, microbial keratitis (infection of the cornea), and chemical burns, yet there is a paucity of ...
Vanessa Rozo +5 more
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Effect Of Andrographolide On Proliferation Of Mycobacterium Canetti
, 2014 The present investigation deals with the anti-mycobacterial prospective value of Andrographolide against Mycobacterium canetti, commonly regarded as smooth variant of the tuberculosis. The bioactive compound andrographolide was extracted from the leaves of Andrographis paniculata. Employing different techniques viz.
Shrivastava, Ashish, Garg, HK
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Mass Spectrometry Imaging Combined With Single-Cell Transcriptional Profiling Reveals the Multidimensional Spatial Distributions and Biosynthetic Pathways of Medicinal Components in Andrographis paniculata. [PDF]
Plant Biotechnol JABSTRACT The synthesis and accumulation of active ingredients in medicinal plants are distributed in specific organs, tissues, and cell types, which are important for the exploitation of medicinal plants. However, the fine distribution of active ingredients is difficult to know. Here, the system of mass spectrometry imaging (MSI) integrated with single‐
Zeng H +14 more
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Study on the mechanism of andrographolide activation
Frontiers in Neuroscience, 2022 Andrographolide is a natural antibiotic that has the ability to dispel heat, detoxify, reduce inflammation, and relieve pain. Recent research has shown that it can exert anti-inflammatory effects via multiple pathways and multiple targets (mediated by NF-κB, JAK/STAT, T cell receptor, and other signaling pathways).
Qihan Cai +9 more
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Journal of Pharmacological Sciences, 2021 Schizophrenia is one of the foremost psychological illness around the world, and recent evidence shows that inflammation and oxidative stress may play a critical role in the etiology of schizophrenia.
Xiying Wang +3 more
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