Results 271 to 280 of about 28,478 (352)

BRD9 inhibition as potential treatment option for testicular germ cell tumors

open access: yesAndrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen   +5 more
wiley   +1 more source

Fetal exposure to a mixture of endocrine‐disrupting chemicals and biomarkers of male fecundity: A population‐based cohort study

open access: yesAndrology, EarlyView.
Abstract Background Fetal exposure to endocrine‐disrupting chemicals (EDCs) has been associated with reduced male fecundity, but with few studies considering chemical mixtures. Objectives We assessed the association between fetal exposure to a mixture of EDCs and biomarkers of male fecundity in young adulthood.
Sidsel Dan Hull   +11 more
wiley   +1 more source

The mythological and archaeological perspectives on penectomy and orchiectomy: The case of Cybele and Attis

open access: yesAndrology, EarlyView.
Abstract Castration has been a significant theme in mythology, religious traditions, and historical practices, often symbolizing transformation, sacrifice, and divine punishment. While the term is frequently associated with orchiectomy (removal of the testes), this study argues that penectomy (removal of the penis) must also be considered, particularly
Coskun Kaya
wiley   +1 more source

The absence of both RIBC1 and RIBC2 induces decreased sperm motility and litter size in male mice

open access: yesAndrology, EarlyView.
Abstract Background RIBC1 (RIB43A domain with coiled‐coils 1) and RIBC2 (RIB43A domain with coiled‐coils 2) are homolog proteins of RIB43a which is localized to microtubules in the cilia and flagella of unicellular organisms. Cryo‐electron microscopy and artificial intelligence studies showed that RIBC1 and RIBC2 are microtubule inner proteins (MIPs ...
Kento Katsuma   +7 more
wiley   +1 more source

Semen quality in patients with testicular cancer is associated with age and with greatly elevated levels of beta human chorionic gonadotropin

open access: yesAndrology, EarlyView.
Abstract Background Poor semen quality is a well‐known feature in patients with testicular germ cell tumours (GCTs) at the time of diagnosis but the underlying biological reasons are incompletely understood. Objectives This study aimed to identify GCT‐specific clinical factors that are involved with poor semen quality in GCT patients.
Klaus‐Peter Dieckmann   +9 more
wiley   +1 more source

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