Results 71 to 80 of about 31,443 (286)

Stage‐Specific Racial Disparities in Prostate Cancer Survival Outcomes

The Prostate, EarlyView.
ABSTRACT Background Racial disparities in prostate cancer (PCa) survival are inconsistently reported. Methods We evaluated long‐term survival in 976 men from the NCI–Maryland PCa case‐control study, stratified by disease stage. Results There were no survival differences observed between African American (AA) and European American (EA) men with Stage 1 ...
Tsion Zewdu Minas, Eboneé Nicole Butler, Samuel Mwakisha Mwamburi, Tiffany H. Dorsey, Deepa Bedi, Windy Dean‐Colomb, Christopher A. Loffredo, Stefan Ambs, Clayton Yates   +8 more
wiley   +1 more source

Evaluation of Time to Metastasis After Prostatectomy as a Prognostic Factor in Patients With Metachronous mHSPC: A Secondary Analysis of the SWOG‐1216 Phase 3 Trial

The Prostate, EarlyView.
ABSTRACT Background The prognostic significance of time to metastasis (TTM) following radical prostatectomy in patients with metachronous metastatic hormone‐sensitive prostate cancer (mHSPC) remains uncertain. We performed a secondary analysis of patient‐level data from the phase 3 SWOG 1216 randomized clinical trial to evaluate whether TTM is ...
Nicolas Sayegh, Yeonjung Jo, Umang Swami, Varun Nandakumar, Georges Gebrael, Zeynep Irem Ozay, Haoran Li, Krishnam Goel, Benjamin L. Maughan, Melissa Plets, Maha H. A. Hussain, Tanya B. Dorff, Primo N. Lara Jr., Amir Goldkorn, Seth P. Lerner, Neeraj Agarwal   +15 more
wiley   +1 more source

Is There a Relevant Clinical Impact in Differentiating Idiopathic versus Unexplained Male Infertility?

The World Journal of Men's Health, 2023
Purpose: Overall, male factor infertility (MFI) accounts for up to 50% of etiologies of couple’s infertility, with almost 30% of MFI cases being idiopathic in nature. Idiopathic MFI does not support a tailored treatment work-up in clinical practice.
Christian Corsini, Luca Boeri, Luigi Candela, Edoardo Pozzi, Federico Belladelli, Paolo Capogrosso, Giuseppe Fallara, Nicolò Schifano, Daniele Cignoli, Eugenio Ventimiglia, Alessia D’Arma, Massimo Alfano, Francesco Montorsi, Andrea Salonia   +13 more
doaj   +1 more source

Circulating Tumor Cell Synaptophysin and Androgen Receptor Expression Reflect Prostate Cancer Phenotypes in Metastatic Disease

The Prostate, EarlyView.
ABSTRACT Background Chronic exposure to androgen receptor (AR)‐targeted therapies can drive lineage plasticity, leading to treatment resistance and neuroendocrine prostate cancer (NEPC), characterized by loss of AR expression and acquisition of neuroendocrine (NE) markers including synaptophysin (SYP). We evaluated concordance between circulating tumor
Ethan Lo, Alisa Clein, Michael Tam, Sara Trimble, Michael Hardin, Arturo Ramirez, Eric Kaldjian, Evan Y. Yu, Heather H. Cheng, Todd A. Yezefski, Andrew C. Hsieh, Petros Grivas, Bruce Montgomery, Peter S. Nelson, Michael T. Schweizer, Daniel E. Sabath, Steven Blinka   +16 more
wiley   +1 more source

Real‐World HRR Testing Pathways and Patterns of Detected Alterations in Prostate Cancer From the Multinational ARON‐3 Study

The Prostate, EarlyView.
ABSTRACT Background Homologous recombination repair (HRR) testing is increasingly relevant in prostate cancer because it identifies patients who may benefit from biomarker‐guided treatment strategies, including poly(ADP‐ribose) polymerase inhibitors (PARPi).
Lorena Incorvaia, Veronica Mollica, Ondřej Fiala, Kazutoshi Fujita, Yüksel Ürün, Bohuslav Melichar, Javier Molina‐Cerrillo, Teresa Alonso‐Gordoa, Umberto Basso, Maria T. Bourlon, Emmanuel Seront, Ugo De Giorgi, Maria José Juan Fita, Pasquale Rescigno, Tarek Taha, Fernando C. Maluf, Alexandr Poprach, Simona De Summa, Tomas Buchler, Luca Galli, Jindrich Kopecky, Gaetano Aurilio, Jakub Kucharz, Carlo Messina, Gabriel Berlingieri Polho, Sarah Scagliarini, Francesco Grillone, Diogo Assed Bastos, Luigi Formisano, Gian Paolo Spinelli, Alessandra Mosca, Alessandro Rizzo, Aristotelis Bamias, Fernando Sabino Marques Monteiro, Andrey Soares, Francesco Massari, Andrew J. Armstrong, Matteo Santoni   +37 more
wiley   +1 more source

Probiotics Outperform Antioxidants in Improving Semen Parameters of Men with Idiopathic Oligoasthenoteratozoospermia: A Randomized Controlled Trial [PDF]

Iranian Journal of Medical Sciences
Background: Idiopathic oligoasthenoteratozoospermia (iOAT) treatment still poses significant challenges. This study aims to compare the therapeutic efficacy of probiotics on sperm parameters of iOAT patients with placebo and antioxidants.Methods: In this
Farshad Gholipour, Davoud Gharakhani, Amirhossein Rahavian, Mahdi Norouzi, Mohammadreza Hajian, Serajoddin Vahidi, Mohammad Javad Nazarpour, Farbod Khorrami   +7 more
doaj   +1 more source

Vitamin D and Male Erectile Function: An Updated Review

The World Journal of Men's Health, 2021
Literature support that vitamin-D is important for different systems of the human body including, but not limited to endocrine and immune systems, vasculature and endothelial function of the body.
Onder Canguven, Ahmad H. Al Malki
doaj   +1 more source

Role of testicular fine‐needle aspiration in the modern male reproductive urologist′s practice

UroPrecision, EarlyView.
Abstract Background Azoospermia affects 10%–15% of infertile men, with non‐obstructive azoospermia (NOA) most often managed by microdissection testicular sperm extraction (mTESE). Despite AUA/ASRM guidelines recommending mTESE, some urologists employ testicular fine‐needle aspiration (TFNA) mapping as a diagnostic adjunct.
Parth Joshi, Jordan Kassab, Vivek Aslot, Richard Schoor   +3 more
wiley   +1 more source

Reversal of Diabetic Complications in Andrology Parameters of Alloxan-Induced Diabetic Male Wistar Rats Treated with Cleome rutidosperma Leaves

Folia Veterinaria, 2020
Male infertility is one of the complications associated with diabetes mellitus. This study reported the effect of managing experimentally-induced diabetes in male Wistar rats with Cleome rutidosperma leaf extract at doses of 100 mg.kg−1, 200 mg.kg−1 or ...
Oridupa O. A., Ovwighose N. O., Aina O. O., Saba A. B.   +3 more
doaj   +1 more source

Prevalence of HCMV, HHV‐6, and HSV‐1/2 in the semen of men attending infertility clinics and their association with semen parameters

UroPrecision, EarlyView.
Abstract Background Viral infections have been identified as potential disruptors of male reproductive health. This study aimed to investigate the prevalence of human cytomegalovirus (HCMV), human herpesvirus 6 (HHV‐6), and herpes simplex virus types 1 and 2 (HSV‐1/2) DNA in semen samples from fertile and infertile men within the potential impact of ...
Seyedeh Zahra Hashemi, Neda Pirbonyeh, Fahime Edalat, Narges Eslami, Saeed Tajik, Arash Letafati, Jamal Sarvari, Afagh Moattari   +7 more
wiley   +1 more source