Results 111 to 120 of about 17,064 (267)

The Concise Guide to PHARMACOLOGY 2015/16:Nuclear hormone receptors [PDF]

, 2015
The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org),
Aldrich, R, Alexander, SPH, Attali, B, Back, M, Barnes, NM, Bathgate, R, Beart, PM, Becirovic, E, Benson, HE, Biel, M, Birdsall, NJ, Boison, D, Brauner-Osborne, H, Broeer, S, Bryant, C, Burnstock, G, Burris, T, Cain, D, Calo, G, Chan, SL, Chandy, KG, Chiang, N, Christakos, S, Christopoulos, A, Chun, JJ, Chung, J-J, Cidlowski, JA, Clapham, DE, Connor, MA, Coons, L, Cox, HM, Dautzenberg, FM, Davies, JA, Dent, G, Douglas, SD, Dubocovich, ML, Edwards, DP, Faccenda, E, Farndale, R, Fong, TM, Forrest, D, Fowler, CJ, Fuller, P, Gainetdinov, RR, Gershengorn, MA, Goldin, A, Goldstein, SAN, Grimm, SL, Grissmer, S, Gundlach, AL, Hagenbuch, B, Hammond, JR, Hancox, JC, Hartig, S, Hauger, RL, Hay, DL, Hebert, T, Hollenberg, AN, Holliday, ND, Hoyer, D, Ijzerman, AP, Inui, KI, Ishii, S, Jacobson, KA, Jan, LY, Jarvis, GE, Jensen, R, Jetten, A, Jockers, R, Kaczmarek, LK, Kanai, Y, Kang, HS, Karnik, S, Kelly, E, Kerr, ID, Korach, KS, Lange, CA, Larhammar, D, Leeb-Lundberg, F, Leurs, R, Lolait, SJ, Macewan, D, Maguire, JJ, Marrion, N, May, JM, Mazella, J, McArdle, CA, McDonnell, DP, Michel, MC, Miller, LJ, Mitolo, V, Monie, T, Monk, PN, Mouillac, B, Murphy, PM, Nahon, J-L, Nerbonne, J, Nichols, CG, Norel, X, Oakley, R, Offermanns, S, Palmer, LG, Panaro, MA, Pawson, AJ, Perez-Reyes, E, Pertwee, RG, Peters, JA, Pike, JW, Pin, JP, Pintor, S, Plant, LD, Poyner, DR, Prossnitz, ER, Pyne, S, Ren, D, Richer, JK, Rondard, P, Ross, RA, Sackin, H, Safi, R, Sanguinetti, MC, Sartorius, CA, Segaloff, DL, Sharman, JL, Sladek, FM, Southan, C, Stewart, G, Stoddart, LA, Striessnig, J, Summers, RJ, Takeda, Y, Tetel, M, Toll, L, Trimmer, JS, Tsai, M-J, Tsai, SY, Tucker, S, Usdin, TB, Vilargada, J-P, Vore, M, Ward, DT, Waxman, SG, Webb, P, Wei, AD, Weigel, N, Willars, GB, Winrow, C, Wong, SS, Wulff, H, Ye, RD, Young, M, Zajac, J-M   +151 more
core   +4 more sources

Androstane Alkaloids from Musk of Moschus moschiferus.

ChemInform, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
Sei-Ryang, Oh, Jong Pill, Lee, Seung-Yeup, Chang, Dong-Hyuk, Shin, Kyung-Seop, Ahn, Byung-Sun, Min, Hyeong-Kyu, Lee   +6 more
openaire   +3 more sources

Molecular Basis of Metabolism-Mediated Conversion of PK11195 from an Antagonist to an Agonist of the Constitutive Androstane Receptor [PDF]

, 2017
Bryan Mackowiak, Linhao Li, Matthew A. Welch, Daochuan Li, Jace W. Jones, Scott Heyward, Maureen A. Kane, Peter W. Swaan, Hongbing Wang   +8 more
openalex   +1 more source

Synthesis and in vivo evaluation of non-hepatotoxic acetaminophen analogs [PDF]

, 2007
A series of acetaminophen (APAP) analogs, 2-(1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)-N-(4-hydroxyphenyl)alkanecarboxamides, bearing a heterocyclic moiety linked to the p-acylaminophenol fragment, were prepared in a general project to develop APAP ...
Bazan, Nicolas G., Marcheselli, Victor L., Matía Martín, Ma de la Paz, Minguez Ortega, José Miguel, Mukherjee, Pranab K., Paul, Dennis, Rodríguez de Turco, Elena B., Sunkel Letelier, Carlos, Trudell, Mark L., Vaccarino, Anthony L., Xu, Liang, Álvarez-Builla Gómez, Julio   +11 more
core   +3 more sources

A practical approach [PDF]

, 2020
Kollmeier, Annette Sophie, Parr, Maria Kristina   +1 more
core   +1 more source

Metformin represses drug – induced expression of CYP2B6 by the constitutive androstane receptor phosphorylation

Ожирение и метаболизм, 2014
Currently, metformin is a major hypoglycemic agents for the treatment of type 2 diabetes. The main antihyperglycemic effect of metformin - suppression of hepatic gluconeogenesis and glycolysis.

doaj   +1 more source

Multiple Genes Exhibit Phenobarbital-Induced Constitutive Active/Androstane Receptor–Mediated DNA Methylation Changes during Liver Tumorigenesis and in Liver Tumors [PDF]

, 2009
Jennifer M. Phillips, Jay I. Goodman
openalex   +1 more source

Xenobiotic induction of cytochrome P450 2B1 (CYP2B1) is mediated by the orphan nuclear receptor constitutive androstane receptor (CAR) and requires steroid co-activator 1 (SRC-1) and the transcription factor Sp1 [PDF]

, 2001
Roongsiri Muangmoonchai, Despina Smirlis, Siew Cheng Wong, Mina Edwards, Ian Phillips, Elizabeth A. Shephard   +5 more
openalex   +1 more source

Methadone Induces the Expression of Hepatic Drug-Metabolizing Enzymes through the Activation of Pregnane X Receptor and Constitutive Androstane Receptor [PDF]

, 2009
Antonia H. Tolson, Haishan Li, Natalie D. Eddington, Hongbing Wang   +3 more
openalex   +1 more source

Detection and metabolic investigations of a novel designer steroid: 3-chloro-17α-methyl-5α-androstan-17β-ol

, 2015
In 2012, seized capsules containing white powder were analyzed to show the presence of unknown steroid-related compounds. Subsequent gas chromatography–mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) investigations identified a mixture of ...
Blakey, Karen, Boyd, Sue, Cawley, Adam T., Handelsman, David J., Heather, Alison, McGrath, Kristine C., McLeod, Malcolm D., Waller, Christopher C., Willis, Anthony C.   +8 more
core   +1 more source