Results 41 to 50 of about 2,751 (216)

Analytical methodologies for the determination of pharmaceuticals and personal care products (PPCPs) in sewage sludge: A critical review [PDF]

open access: yes, 2019
Producción CientíficaSeveral analytical approaches have been developed for the determination of emerging pollutants (EPs), including pharmaceuticals and personal care products (PPCPs) in environmental matrices. This paper reviews the sample preparation
Barrado Esteban, Enrique   +3 more
core   +2 more sources

Discovery of ferroelectricity in natural product androstane

open access: yesDiscover Materials, 2023
Abstract Progesterone and its derivatives attracted widespread interest because of their applications in medicine, health care and birth control, which is the main active ingredient of contraceptive pills known as one of the five chemistry discoveries that changed human life.
Ren-Gen Xiong   +2 more
openaire   +2 more sources

The ALS‐associated E425K mutation uncouples DNAJC7 from the Hsp70 chaperone cycle

open access: yesThe FEBS Journal, EarlyView.
DNAJC7 is a J‐domain protein that plays a key role in protein quality control by regulating Hsp70 activity and preventing protein aggregation. We find that the ALS‐associated E425K mutation in DNAJC7 disrupts productive interaction and activation of Hsp70, thereby blocking the transfer and refolding of client proteins such as TDP‐43.
Bar Elmaleh   +2 more
wiley   +1 more source

Novel inhibitor discovery against aromatase through virtual screening and molecular dynamic simulation [PDF]

open access: yes, 2013
Inhibition of aromatase (CYTP450) as a key enzyme in the estrogen biosynthesis could result in regression of estrogen-dependent tumors and even preventing the promotion of breast cancer.
Asadabadi, Ebrahim Barzegari   +4 more
core  

Olfactory sensitivity to steroid glucuronates in Mozambique tilapia suggests two distinct and specific receptors for pheromone detection [PDF]

open access: yes, 2014
Cichlids offer an exciting opportunity to understand vertebrate speciation; chemical communication could be one of the drivers of African cichlid radiation.
Canario, Adelino V. M.   +2 more
core   +1 more source

Effect of live‐high, train‐low strategy induced by chronic low‐dose carbon monoxide exposure on haematological parameters and performance in trained individuals

open access: yesExperimental Physiology, EarlyView.
Abstract Altitude training enhances haematological adaptations and endurance at sea level, typically requiring exposure to ∼2500 m altitude for 3–4 weeks. Emerging evidence suggests that low‐dose carbon monoxide (CO) inhalation might mimic hypoxia and might be used by elite athletes.
Simone Villanova   +3 more
wiley   +1 more source

Béta-laktámokhoz vezető dominó reakció: átmenetifém-katalizált ketén képződés és cikloaddíció szintetikus és elméleti vizsgálata = Domino transition metal-catalysed ketene formation — cycloaddition reactions leading to beta-lactams. Synthetic and theoretical aspects. [PDF]

open access: yes, 2012
Reakciókinetikai, spektroszkópiai és elméleti kémiai számítási módszerekkel tisztáztuk a kobalt-katalizált etil-diazoacetát karbonilezés mechanizmusát. Kvantumkémiai számításokkal vizsgáltuk diazometán és etil-diazoacetát reakcióját nikkel-tetrakarbonil ...
Balogh, János   +6 more
core  

Multiselective Diels–Alder Reaction of α-Arylacroleins Catalyzed by Boron Tribromide-Assisted Chiral Phosphoric Acids [PDF]

open access: yes, 2022
A multiselective Diels–Alder (DA) reaction of α-arylacroleins with cyclopentadiene using BBr3-assisted chiral BINOL-derived phosphoric acid catalysts has been developed.
Hatano, Manabu   +3 more
core   +1 more source

A review of xenobiotic membrane transporter expression within the human placenta: Lessons gained from primary tissue and in vitro methodologies

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A summary of the current knowledge around membrane transporter expression in the most widely used in vitro models of human trophoblasts, including primary placental tissue, cancer cell lines and trophoblast stem cells, as well as the techniques to attempt to mimic the human placenta in vivo.
Rhiannon Pass   +2 more
wiley   +1 more source

The metabolism of anabolic-androgenic steroids in the greyhound

open access: yes, 2013
BACKGROUND Effective control of the use of anabolic-androgenic steroids (AASs) in animal sports is essential in order to ensure both animal welfare and integrity.
Ambrus, Joseph I.   +8 more
core   +1 more source

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