Results 171 to 180 of about 1,570 (204)

A synthetic androstene derivative and a natural androstene metabolite inhibit relapsing–remitting EAE

Journal of Neuroimmunology, 2002
Experimental allergic encephalomyelitis (EAE), a Th1 polarized demyelinating disease of the central nervous system (CNS), shares many pathological and clinical similarities with multiple sclerosis (MS), and thus represents an attractive animal model for this disease. The goal of this study was to evaluate the suppressive effects of fluasterone (HE2500),
Offner, Halina, Zamora, Alex, Drought, Heather, Matejuk, Agata, Auci, Dominick, Morgan, Elizabeth, Vandenbark, Arthur, Reading, Christopher   +7 more
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Hydroalkoxycarbonylation of androstene derivatives

Tetrahedron Letters, 1992
Abstract Various esters are conveniently prepared by direct hydroesterification of the corresponding androstene derivatives with alcohols and carbon monoxide catalyzed by a palladium-phosphine catalyst with high stereoselectivity.
Szilárd Törös, Bálint Heil, György Gálik, Zoltán Tuba   +3 more
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In vivo 4-androstene-3,17-dione and 4-androstene-3β,17β-diol supplementation in young men

European Journal of Applied Physiology, 2000
To determine if known androgenic hormone precursors for testosterone in the androgen pathway would be readily transformed to testosterone, eight male subjects [mean age 23.8 (SEM 3) years, bodymass 83.1 (SEM 8.7) kg, height 175.6 (SEM 8.5) cm] underwent a randomized, double-blind, cross-over, placebo-controlled oral treatment with 200 mg of 4 ...
Earnest, Conrad P., Olson, Mark A., Broeder, Craig E., Breuel, Kevin F., Beckham, Susan G.   +4 more
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An improved radioimmunoassay for 4-androstene-3,17-dione

Steroids, 1977
A radioimmunoassay using an antiserum produced against 6beta-hydroxy-4-androstene-3,17-dione-6-succinyl-BSA conjugate is described which permits the rapid determination of 4-androstene-3,17-dione in multiple serum samples that are purified by column chromatography on neutral alumina. Steroids which reacted significantly with the antiserum were found to
L N, Parker, P K, Grover, W D, Odell
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Aromatization of Δ-androstene-3,17-dione, 19-hydroxy-Δ4-androstene-3,17-dione, and 19-oxo-Δ-androstene-3,17-dione at a common catalytic site in human placental microsomes

Biochemistry, 1977
Estrogen is believed to be biosynthesized from androstenedione in placental microsomes by a multienzyme pathway in which 19-hydroxyandrostenedione and 19-oxoandrostenedione (or the hydrated form) are obligatory intermediates. However, both 19-hydroxyandrostenedione and 19-oxoandrostenedione competitively inhibited aromatization of androstenedione, and ...
William G. Kelly, Dianne Judd, Ann Stolee   +2 more
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Steroids, XL. 15‐(hydroxymethyl)androstene and ‐estratriene derivatives

Liebigs Annalen der Chemie, 1988
Abstract15α‐Hydroxymethyl‐5‐androstene‐3β,16β,17β‐triol (5d) and 16β‐hydroxy‐15α‐(hydroxymethyl)estratriene derivatives 9 were prepared from the corresponding 15‐hydroxymethylene‐16‐ketones 3 and 4. The configurations of the chiral centers were determined by means of chemical transformations and on the basis of spectroscopic data.
Vincze Irén, Somlai Csaba, Schneider Gyula, Dombi György   +3 more
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ChemInform Abstract: Hydroalkoxycarbonylation of Androstene Derivatives.

ChemInform, 1992
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
S. TOEROES, B. HEIL, G. GALIK, Z. TUBA
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17α-Benzyl-3β,17β-dihydroxy-5-androstene

Acta Crystallographica Section C Crystal Structure Communications, 1994
The asymmetric unit of the title compound, 17α-benzyl-5-androst-5-ene-3β,17β-diol, C 26 H 36 O 2 , contains two molecules, which differ slightly in the conformation of the D ring. Of the four OH groups in the two symmetry-independent molecules, A and B, three participate in O-H...O hydrogen bonding. Crystal packing involves molecules of A forming helix-
S. Stanković, D. Miljković, L. Medić-Mijačević, K. Gaši, C. Courseille   +4 more
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Synthesis of 17-(1,2,3-dithiazole) androstene derivatives

Mendeleev Communications, 2011
17-(1,2,3-Dithiazole) androstene derivatives were synthesized from commercially available Pregnenolone acetate involving the reaction between 3b-acetoxy-20-hydroxyimino-5-pregnene with sulfur monochloride as the key step.
Stanislav A. Amelichev, Alexander S. Shashkov, Igor V. Zavarzin, Oleg A. Rakitin   +3 more
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ChemInform Abstract: Synthesis of 5‐Androstene‐3β,7α,17β‐triol and 5‐Androstene‐3β,7β,17β‐triol.

ChemInform, 2008
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
He‐Ping Li, Peng Yu, Hong‐Jie Zhang, Hong‐Min Liu   +3 more
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