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Current Opinion in Immunology, 1994 Autoimmune hemolytic anemia (AHA) is characterized by the production of Coombs' antibodies, which are responsible for the destruction of red blood cells (RBCs). Analysis of both monoclonal anti-RBC autoantibodies derived from autoimmune New Zealand black mice and transgenic mice expressing a pathogenic IgM anti-RBC autoantibody has considerably ...
Izui, Shozo
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American Journal of Hematology, 2002
AbstractRed blood cell (RBC) autoantibodies are a relatively uncommon cause of anemia. However, autoimmune hemolytic anemia (AIHA) must be considered in the differential diagnosis of hemolytic anemias, especially if the patient has a concomitant lymphoproliferative disorder, autoimmune disease, or viral or mycoplasmal infection. Classifications of AIHA
Bradley C, Gehrs, Richard C, Friedberg
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AbstractRed blood cell (RBC) autoantibodies are a relatively uncommon cause of anemia. However, autoimmune hemolytic anemia (AIHA) must be considered in the differential diagnosis of hemolytic anemias, especially if the patient has a concomitant lymphoproliferative disorder, autoimmune disease, or viral or mycoplasmal infection. Classifications of AIHA
Bradley C, Gehrs, Richard C, Friedberg
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Complications of Autoimmune Hemolytic Anemia
Hematology/Oncology Clinics of North America, 2022Autoimmune hemolytic anemia (AHIA) is the group of acquired autoimmune conditions resulting from the development of autologous antibodies directed against autologous red blood cell antigens resulting in red cell lysis. Beyond the presence, severity, and duration of hemolysis which can lead to symptomatic anemia, additional complications at presentation
Surbhi, Shah, Leslie, Padrnos
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The Indian Journal of Pediatrics, 1998
Immune hemolytic anemia can be either isoimmune or autoimmune. Autoimmune hemolytic anemias (AIHA) consist of group of disorders whose common characteristics are the presence of an antibody which in turn causes short red blood cell (RBC) life. The rate and site of hemolysis and hence the clinical manifestations depends on the type of antibody attached ...
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Immune hemolytic anemia can be either isoimmune or autoimmune. Autoimmune hemolytic anemias (AIHA) consist of group of disorders whose common characteristics are the presence of an antibody which in turn causes short red blood cell (RBC) life. The rate and site of hemolysis and hence the clinical manifestations depends on the type of antibody attached ...
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The Indian Journal of Pediatrics, 2008
To study the clinico-hematological profile and treatment outcome in children suffering from auto immune hemolytic anemia (AIHA).Twelve children were diagnosed with auto immune hemolytic anemia over a period of four years. Direct antiglobulin test was positive in all the cases.
V, Gupta, J, Shukla, B D, Bhatia
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To study the clinico-hematological profile and treatment outcome in children suffering from auto immune hemolytic anemia (AIHA).Twelve children were diagnosed with auto immune hemolytic anemia over a period of four years. Direct antiglobulin test was positive in all the cases.
V, Gupta, J, Shukla, B D, Bhatia
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Medical Clinics of North America, 2017
Autoimmune hemolytic anemia is an acquired autoimmune disorder resulting in the production of antibodies directed against red blood cell antigens causing shortened erythrocyte survival. The disorders can present as a primary disorder (idiopathic) or secondary to other autoimmune disorders, malignancies, or infections.
Howard A, Liebman, Ilene C, Weitz
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Autoimmune hemolytic anemia is an acquired autoimmune disorder resulting in the production of antibodies directed against red blood cell antigens causing shortened erythrocyte survival. The disorders can present as a primary disorder (idiopathic) or secondary to other autoimmune disorders, malignancies, or infections.
Howard A, Liebman, Ilene C, Weitz
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Autoimmune Pathogenesis and Autoimmune Hemolytic Anemia
Seminars in Hematology, 2005Autoimmune hemolytic anemia (AIHA) is an autoimmune disorder in which autoantibodies are directed against an individual's own red blood cells (RBCs), leading to enhanced clearance through Fc receptor (FcR)-mediated phagocytosis. Although there is a large literature relating to clinical aspects of AIHA, relatively little work addresses how IgG ...
John W, Semple, John, Freedman
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Reticulocytopenia in Autoimmune Hemolytic Anemia
Blood, 1956Abstract 1. In a series of 57 cases of autoimmune hemolytic anemia it was found that 25 or 44 per cent had a relative reticulocytopenia at times of hemolytic crisis. The mortality rate in this group was significantly higher than in those who showed a reticulocyte response consistent with the severity of anemia.
W H, CROSBY, H, RAPPAPORT
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Autoimmune hemolytic anemia: A history*
Transfusion Medicine Reviews, 2000UTOIMMUNE HEMOLYTIC anemia (AIHA) is an acquired immunoIogic disease in which the patient's red blood cells (RBCs) are selectively attacked and destroyed (hemolyzed) by autoantibodies produced by the patient's own immune system. These patients generally display the common symptoms of anemia: weakness, pallor, fatigue, and jaundice.
P, Mack, J, Freedman
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Pediatric Clinics of North America, 1980
In autoimmune hemolytic anemia, individuals produce antibodies directed against one of their own erythrocyte membrane antigens. The hemolysis in autoimmune hemolytic anemia is most commonly extravascular rather than intravascular, and the liver and spleen play a major role in the clearance of the antibody-coated cells.
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In autoimmune hemolytic anemia, individuals produce antibodies directed against one of their own erythrocyte membrane antigens. The hemolysis in autoimmune hemolytic anemia is most commonly extravascular rather than intravascular, and the liver and spleen play a major role in the clearance of the antibody-coated cells.
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