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Archives of Internal Medicine, 1975
Warm-type autoantibodies of autoimmune hemolytic anemia (AIHA) are usually IgG but may be IgM or IgA. They are usual Rh specific. Cold-type antibodies are IgM or IgG (Donath-Landsteiner [DL] antibody). IgM antibodies are usually anit-l (occasionally anti-i) and DL antibodies anti-P.
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Warm-type autoantibodies of autoimmune hemolytic anemia (AIHA) are usually IgG but may be IgM or IgA. They are usual Rh specific. Cold-type antibodies are IgM or IgG (Donath-Landsteiner [DL] antibody). IgM antibodies are usually anit-l (occasionally anti-i) and DL antibodies anti-P.
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Hospital Practice, 1985
Rh and ABO incompatibilities, drug reactions, and lupus are a few of the many causes of autoimmune hemolytic anemia. Among the determinants of autoimmunity involved are the class of the antibody, the biochemical composition of the antigen, the distribution of the antigen on the erythrocyte membrane, and the effector cells and molecules that are ...
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Rh and ABO incompatibilities, drug reactions, and lupus are a few of the many causes of autoimmune hemolytic anemia. Among the determinants of autoimmunity involved are the class of the antibody, the biochemical composition of the antigen, the distribution of the antigen on the erythrocyte membrane, and the effector cells and molecules that are ...
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AUTOIMMUNE HEMOLYTIC ANEMIA IN CHILDREN
Pediatric Hematology and Oncology, 2007The clinical and hematological profile and treatment outcome of children with warm autoimmune hemolytic anemia (AIHA) were assessed using retrospective case record analysis. There were 26 (17 idiopathic; 9 secondary) patients with a median age of 11 years. Pallor (100%), fever (39%), and jaundice (59%) were the main presenting complaints.
Rahul, Naithani +5 more
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Human Pathology, 1983
Nowhere in the management of patients with autoimmune hemolytic anemias is the communication between clinician and laboratory personnel more important than in regard to blood transfusion. A clinical decision that blood transfusion is necessary must be tempered by the knowledge that transfusion has a greater-than-usual risk in this setting, both because
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Nowhere in the management of patients with autoimmune hemolytic anemias is the communication between clinician and laboratory personnel more important than in regard to blood transfusion. A clinical decision that blood transfusion is necessary must be tempered by the knowledge that transfusion has a greater-than-usual risk in this setting, both because
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Geoepidemiology of autoimmune hemolytic anemia
Autoimmunity Reviews, 2010Autoantibodies against red blood cell antigens are considered the diagnostic hallmark of AIHA: Direct antiglobulin test (DAT) completed by cytofluorometry and specific diagnostic monoclonal antibodies (mAbs) allow for a better understanding of autoimmune hemolytic anemia (AIHA) triggers. Once B-cell tolerance checkpoints are bypassed, the patient loses
Jean-Francois, Lambert, Urs E, Nydegger
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Autoimmune Hemolytic Anemia in a Dog
Journal of the American Veterinary Medical Association, 1973SUMMARY Autoimmune hemolytic anemia (aha) occurred in a 3½-year-old Cocker Spaniel. The clinical signs and blood values on initial examination were consistent with a diagnosis of aha; however, the results of Coombs’ antiglobulin test were not conclusive until 7 months later.
M D, Avolt, J E, Lund, J C, Pickett
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Treatment of Autoimmune Hemolytic Anemia
Seminars in Hematology, 2005The appropriate therapy of autoimmune hemolytic anemia (AIHA) is dependent on the correct diagnosis and classification of this family of hemolytic disorders. Although the majority of cases are warm AIHA, there are several distinct types of cold AIHA and a number of drug-induced etiologies of AIHA, which must be investigated to determine if stopping a ...
Karen E, King, Paul M, Ness
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Autoimmune Hemolytic Anemia and Cancer
JAMA: The Journal of the American Medical Association, 1965THE OCCURRENCE of overt hemolytic anemia in malignant diseases other than those involving the reticuloendothelial system is uncommon. Approximately 15 cases of overt hemolytic anemia associated with cancer have been reported in the medical literature.
L D, ELLIS, M P, WESTERMAN
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Warm Autoimmune Hemolytic Anemia
Hematology/Oncology Clinics of North America, 2015Warm autoimmune hemolytic anemia (AIHA) is defined as the destruction of circulating red blood cells (RBCs) in the setting of anti-RBC autoantibodies that optimally react at 37°C. The pathophysiology of disease involves phagocytosis of autoantibody-coated RBCs in the spleen and complement-mediated hemolysis.
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Treatment of autoimmune hemolytic anemias
Current Opinion in Hematology, 2001Treatment of autoimmune hemolytic anemias varies depending on whether the patient has autoimmune hemolytic anemia of warm antibody type, cold agglutinin syndrome, paroxysmal cold hemoglobinuria, or autoimmune hemolytic anemia secondary to an underlying disorder.
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