Results 41 to 50 of about 10,596 (213)

Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults. [PDF]

, 2019
Thiamine (vitamin B1) is an essential nutrient that serves as a cofactor for a number of enzymes, mostly with mitochondrial localization. Some thiamine-dependent enzymes are involved in energy metabolism and biosynthesis of nucleic acids whereas others ...
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core   +2 more sources

L‐quebrachitol Modulates the Anti‐convulsant Effects of Carbamazepine Possibly Through Voltage‐gated Sodium Channel Blocking Mechanism in Chicks: In Vivo and In Silico Studies

Brain and Behavior, Volume 15, Issue 7, July 2025.
L‐quebrachitol exhibited significant anticonvulsant effects in PTZ‐induced seizures in chicks, likely through voltage‐gated sodium channel inhibition. In vivo and in silico analyses suggest LQB may synergize with carbamazepine, offering a potential new therapeutic approach for epilepsy management. ABSTRACT Introduction L‐Quebrachitol (LQB), a naturally
Asifa Asrafi, Mohammad Aslam, Ali G. Alkhathami, Md. Sakib Hossain, Imam Hossen Rakib, Md. Sakib Al Hasan, Feroz Khan Nun, Md. Faisal Amin, Muhammad Torequl Islam   +8 more
wiley   +1 more source

Congenital Familial Megaloblastic Anemia [PDF]

Blood, 1971
Abstract Two sisters with a previously unreported megaloblastic anemia unassociated with a deficiency of either folic acid or vitamin B12 are described. Deficiencies of these vitamins were ruled out by standard studies. All other previously reported forms of megaloblastic anemia not secondary to a vitamin deficiency, such as orotic ...
Carol B. Hyman, Beatrice C. Lampkin, Beatrice C. Lampkin, Denman Hammond, Allan Pyesmany, Allan Pyesmany   +5 more
openaire   +3 more sources

Application of Green Cobalt Nanoparticles in the Diet of Broiler Chickens to Improve Sustainable Production and Health

Veterinary Medicine and Science, Volume 11, Issue 4, July 2025.
Nanoparticles, such as green cobalt nanoparticles, are easier to pass through cell membranes in animals and interact rapidly with biological systems. The results indicated that BNCo supplementation at 200 ppm/kg diet produced the best overall performance, demonstrating its potential as an innovative additive for broiler diets.
Fayiz M. Reda, Abdullah S. Alawam, Hemat K. Mahmoud, Mohamed T. El‐Saadony, Ayman S. Salah, Hassan A. Rudayni, Ahmed A. Allam, Karima El‐Naggar, Mahmoud Alagawany, Most Khairunnesa   +9 more
wiley   +1 more source

Severe megaloblastic anemia in a patient with advanced lung adenocarcinoma during treatment with erlotinib: a case report and literature review

BMC Pulmonary Medicine
Background Erlotinib is a first-generation, tyrosine kinase inhibitor of the epidermal growth factor receptor (EGFR-TKI) used for the treatment patients with NSCLC.
Xin Yan, Jingxian Kong, Jiacheng Wang, Caixia Wang, Hongchang Shen   +4 more
doaj   +1 more source

Red blood cell precursor mass as an independent determinant of serum erythropoietin level. [PDF]

, 1998
Serum erythropoietin (sEpo) concentration is primarily related to the rate of renal production and, under the stimulus of hypoxia, increases exponentially as hemoglobin (Hb) decreases.
Beguin, Yves, Cazzola, M., Centenara, E., Cerani, P., Guarnone, R., Rovati, A.   +5 more
core   +1 more source

Vitamin B12 Levels Association with Functional and Structural Biomarkers of Central Nervous System Injury in Older Adults

Annals of Neurology, Volume 97, Issue 6, Page 1190-1204, June 2025.
At low levels of B12, specifically when bound to transcobalamin for cellular uptake, evidence of slower conductivity in the brain could point toward impaired myelin. At high levels of B12, specifically when bound to the biologically inert transport protein haptocorrin, biomarkers of neurodegeneration appear in the serum, indicating neuroaxonal injury ...
Alexandra Beaudry‐Richard, Ahmed Abdelhak, Rowan Saloner, Simone Sacco, Shivany C. Montes, Frederike C. Oertel, Christian Cordano, Nour Jabassini, Kirtana Ananth, Apraham Gomez, Azeen Keihani, Makenna Chapman, Sree Javvadi, Shikha Saha, Adam Staffaroni, Christopher Songster, Martin Warren, John W. Boscardin, Joel Kramer, Bruce Miller, Joshua W. Miller, Ralph Green, Ari J. Green   +22 more
wiley   +1 more source

Evaluation of Clinical Profile and Hematological Parameters of Cases of Megaloblastic Anemia

National Journal of Community Medicine, 2017
Background: Megaloblastic anemia is not uncommon in India. In India, the most common cause of megaloblastic anemia is nutritional where as it is the pernicious anemia in Northern Europe. Aims and objectives: To study age and gender-wise distribution,
Hemang N Suthar, Tejas N Shah
doaj  

Vitamin B12 Deficiency Resembling Acute Leukemia: A Case Report

Journal of Nepal Medical Association, 2021
Vitamin B12 deficiency in children can cause megaloblastic anemia, poor growth, and increased chances of infections. It is an important reversible cause of bone marrow suppression which at the time of presentation can mimic hematological malignancy ...
Nisha Sharma, Saru kunwar, Anil Kumar Shrestha   +2 more
doaj   +1 more source

Novel Homozygous Variant in the SLC19A2 Gene Causing Thiamine Responsive Megaloblastic Anemia Syndrome: A Disease to Be Considered in Diabetes Clinics

Endocrinology Research and Practice
Thiamine-responsive megaloblastic anemia (TRMA) syndrome is a rare syndrome with an autosomal recessive manner that develops due to a mutation in the SLC19A2gene.
Burak Canvar Helvacı, Hanife Saat , Sema Hepsen, Özant Helvacı, Erman Çakal   +4 more
doaj   +1 more source