Results 141 to 150 of about 35,287 (246)

Sickle cell disease implicated in the development of severe dengue: A pediatric case series. [PDF]

Rev Soc Bras Med Trop
Hernández MR, Suarez AG, Redondo HP, Moneriz C.   +3 more
europepmc   +1 more source

A Phase 1 Microtracer Study Evaluating the Mass Balance, Excretion, and Pharmacokinetics of Osivelotor in Healthy Participants

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Osivelotor (GBT021601) is an orally bioavailable, small molecule hemoglobin polymerization inhibitor in clinical development for the treatment of sickle cell disease (SCD). In this Phase 1 study, the disposition of osivelotor was assessed using accelerator mass spectrometry (AMS) after a single oral 200‐mg dose containing a microtracer amount ...
Eric I. Zimmerman, Ernesto Callegari, Raman Sharma, Adeyemi Adenola, Jessica Volpe, Karthik Seetharaman, Chenghong Zhang, Kenneth Duchin, Gregory S. Walker   +8 more
wiley   +1 more source

Effect of health educational intervention on early detection of sickle cell disease among adolescent population in tribal areas of East Singhbhum district, Jharkhand: A study protocol. [PDF]

PLoS One
Bhattacharjee S, Begum J, Shetty RS, Ali SI, Jha RR, Kujur A, Ansari MA.   +6 more
europepmc   +1 more source

Trends in the burden of sickle cell disorders in Sierra Leone, 1990-2023: An analysis of Global Burden of Disease Study 2023 estimates. [PDF]

PLoS One
Faulkner MMJ, Jalloh F, Foray FM, Gborie SL, Jalloh MB.   +4 more
europepmc   +1 more source

Common Hematologic Emergencies—Acute Promyelocytic Leukemia and Microangiopathic Hemolytic Anemias—A Pivotal Role of Clinical Laboratory

International Journal of Laboratory Hematology, Volume 48, Issue 3, Page 521-530, June 2026.
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova, Nicolas Ulrich Edgar, Anton V. Rets   +2 more
wiley   +1 more source

Decoding thalassemia and sickle cell disease: advances in molecular technologies for comprehensive variant detection. [PDF]

Front Genet
Foord E, Sairafi D, Berg M, Westerling S, Adigun T, Uzunel M, Papasavva T, Uhlin M.   +7 more
europepmc   +1 more source

What is the best approach to blood transfusion in sickle cell disease? A scientometric analysis and literature review

Transfusion Medicine, Volume 36, Issue 3, Page 211-221, June 2026.
Abstract Background Blood transfusion remains a cornerstone in the management of sickle cell disease (SCD); however, it is frequently complicated by red cell alloimmunisation. A significant debate persists within the scientific community regarding the optimal strategy to mitigate this risk: the traditional, pragmatic approach of serologic phenotyping ...
Christiane Ruffato Carminati, Lucas Fernandes Ananias, Saulo Fernando Moreira da Silva, Anna Cecília Dias Maciel Carneiro, Helio Moraes de Souza, Sarah Cristina Sato Vaz Tanaka, Fernanda Bernadelli De Vito   +6 more
wiley   +1 more source

Prevalence of parvovirus B19 infection in patients with hematological diseases in the Western Brazilian Amazon. [PDF]

Hematol Transfus Cell Ther
de Souza PHR, Barbosa AN, de Oliveira LC, Mineiro LS, de Abreu RS, Alves CEC, Mejía MDCC, Naveca FG, Pontes GS.   +8 more
europepmc   +1 more source

Addressing racial disparities in representation across blood, stem cell and organ and tissue donor pools

Vox Sanguinis, Volume 121, Issue 6, Page 710-721, June 2026.
Abstract Background and Objectives Adequate representation of donors from diverse ancestral populations in blood, stem cell and organ transplantation is critical to ensuring equitable access to these lifesaving therapies. Because of population‐level differences in genetic markers, patients from racialized groups may have unique transfusion and ...
Bonnie Lu, Sylvia Okonofua, Farnaz Farahbakhsh, Rupal Hatkar, Lauren Sano, Margarita Conway, Marie‐Claire Kapesa, Manuel Escoto, Murdoch Leeies, Warren B. Fingrut   +9 more
wiley   +1 more source

Should Sickle Cell Disease Be Considered a Cancer Predisposition Syndrome? [PDF]

Children (Basel)
Casadessus E, Pastore Y, Pincez T.
europepmc   +1 more source