Results 141 to 150 of about 71,196 (274)

Pulmonary hypertension in adolescents with sickle cell disease [PDF]

, 2016
Sickle cell disease consists of a group of disorders that have a similar mutation in at least one of the beta-globin chains of hemoglobin. This results in a change of the hemoglobin to sickle shaped cells when in the deoxygenated state.
Akinyemi, Katherine
core   +1 more source

Unheard and Under‐Supported: Health‐Related Quality of Life in Children, Adolescents, and Young Adults With Sickle Cell Disease

Pediatric Blood &Cancer, Volume 73, Issue 5, May 2026.
ABSTRACT Background Sickle cell disease (SCD) is an autosomal recessive hemoglobinopathy affecting millions of individuals worldwide. The clinical expression and psychosocial burden of SCD vary widely across geographical, cultural, and healthcare system contexts, underscoring the need for setting‐specific approaches to assessment.
Desiré Fantasia, Giulia Reggiani, Elizabeth J. Maran, Maria Elisa Delle Fave, Ilaria Baido, Anna Chiara Frigo, Maria Paola Boaro, Raffaella Colombatti   +7 more
wiley   +1 more source

Molecular Methods for Rare Hemoglobinopathy Cases: First Brazilian Report of Pediatric Siblings with Hb O‐Arab and Alpha‐Thalassemia

Pediatric Blood &Cancer, Volume 73, Issue 5, May 2026.
ABSTRACT Hemoglobinopathies are prevalent globally; diagnosis is complex in high genetic admixture populations like Brazil. We report, in two pediatric siblings, the first documented cases in Brazil of heterozygosity for hemoglobin (Hb) O‐Arab with coinheritance of α‐thalassemia (αα/−α4.2; −α3.7/−α4.2), resulting in microcytic and hypochromic anemia ...
Elisângela de Souza Miranda Muynarsk, Amanda Cristina Meneguetti Berti, Bárbara Braga Vieira Marques, Victoria Simões Bernardo, Flaviene Felix Torres, Ingrid Souza Dias, Vanessa da Silveira Ramos de Castro, Gabriela Alves Bernardino, Danilo Grünig Humberto da Silva, Edis Belini‐Júnior   +9 more
wiley   +1 more source

Apneia obstrutiva do sono em portadores da anemia falciforme Obstructive sleep apnea in sickle cell disease carriers

Revista Brasileira de Hematologia e Hemoterapia, 2010
A Síndrome da Apneia Obstrutiva do Sono (SAOS) é definida como episódios recorrentes de obstrução completa ou parcial das vias aéreas superiores que ocorrem durante o sono.
Cristina Salles, Regina T. T. Ramos, Marcos A. Matos   +2 more
doaj  

Acute Soft Head Syndrome, A Rare Complication of Sickle Cell Anemia: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Acute soft head syndrome (ASHS) is a rare clinical complication of sickle cell disease (SCD). It presents as a progressive, non‐traumatic, and tender swelling of one or more areas of the scalp. Aetiopathophysiology is still less understood but hypothesized to be a result of loss of cortical skull bone integrity from increased extramedullary ...
Mohammed Nuru‐Deen Fuseini, John G. G. Banin, Suabir Sulemana   +2 more
wiley   +1 more source

G‐CSF for Mobilizing CD34+ Cells in Individuals With SCD: A Word of Caution

American Journal of Hematology, Volume 101, Issue 6, Page 1178-1181, June 2026.
Akshay Sharma, Allistair Abraham, Monica Bhatia, María Cancio, Sonali Chaudhury, Selim Corbacioglu, Gregory M. T. Guilcher, Ashish O. Gupta, Rabi Hanna, Matthew M. Heeney, Tami John, Lakshmanan Krishnamurti, James L. LaBelle, Hemalatha G. Rangarajan, Shalini Shenoy, Elizabeth Stenger, Crawford Strunk, Courtney D. Fitzhugh   +17 more
wiley   +1 more source

Investigation of Red Blood Cell Properties on Impedance Signatures Generated in a Coulter Counter

International Journal for Numerical Methods in Biomedical Engineering, Volume 42, Issue 5, May 2026.
Numerical simulations predicting red blood cell (RBC) dynamics and their electrical signatures in a Coulter counter have been performed, enhancing our understanding of how RBC deformability influences these measurements—traditionally used for counting and sizing.
Pierre Pottier, Pierre Taraconat, Jean‐Philippe Gineys, Damien Isèbe, Franck Nicoud, Simon Mendez   +5 more
wiley   +1 more source

Anemia Among Hospitalized Children in a Ghanaian Pediatric Emergency Unit: A Prospective Observational Study of Prevalence, Associated Factors, and Hematologic Patterns

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Anemia remains a major contributor to pediatric morbidity and mortality in sub‐Saharan Africa, yet contemporary data from tertiary pediatric emergency settings are limited, particularly among children older than 5 years. This study assessed the prevalence, factors associated with anemia, hematological characteristics, and ...
Serwah Bonsu Asafo‐Agyei, Emmanuel Ameyaw, Samuel Blay Nguah, Vivian Paintsil, Akua Afriyie Ocran   +4 more
wiley   +1 more source

Carbohydrate‐Based Drug Discovery: Synthetic Strategies and Clinical Applications

Israel Journal of Chemistry, Volume 66, Issue 3, May 2026.
The picture depicts the molecules discussed in the review. On the left side, the general scaffold of sugars is shown. Next to it are four carbohydrate‐based molecules, including remdesivir, islatravir, empagliflozin, and Globo‐H. Remdesivir and islatravir contain a substituted ribose ring attached to a modified nucleobase.
Stephan Scheeff, Jemma Arakelyan, Billy Wai‐Lung Ng   +2 more
wiley   +1 more source

The impact of low‐dose aspirin on hemoglobin levels in pregnancy: A secondary analysis of a randomized controlled trial for prevention of hypertensive disorders of pregnancy

International Journal of Gynecology &Obstetrics, Volume 173, Issue 2, Page 982-988, May 2026.
Abstract Objectives This study evaluates the association of low‐dose aspirin (LDA) with hemoglobin (Hb) levels during pregnancy and explores how changes in Hb levels relate to hypertensive disorders of pregnancy (HDP). Methods This secondary analysis of a randomized controlled trial comprised 249 pregnant women recruited from a regional hospital in ...
N. M. Ngcobo, V. Dorsamy, C. Bagwandeen, P. Z. Mkhize, J. Moodley   +4 more
wiley   +1 more source