Development of a Clinical Severity Score for Indian Sickle Cell Anaemia Patients
ABSTRACT Background Sickle cell anaemia (SCA) is a monogenic disorder but shows variable disease severity. We evaluated the utility of paediatric severity scores (PSS) in Indian patients and developed two modified scores: Indian Severity Score 1 (ISS1) by adding four clinical parameters to PSS, and ISS2 by excluding four biochemical measures from ISS1.
Suraj S. Nongmaithem +6 more
wiley +1 more source
The role of interleukin-1 beta as an early biomarker for renal dysfunction in Egyptian sickle cell disease patients. [PDF]
Nasr NM +3 more
europepmc +1 more source
Prevalence of Low Bone Mineral Density Increases With Age in Sickle Cell Disease
ABSTRACT Introduction Skeletal complications are common in sickle cell disease (SCD). We previously showed that the prevalence of low areal bone mineral density (aBMD) increased with age in a pediatric SCD cohort, even after adjusting for short stature. Data on age‐related aBMD trends in young adults is lacking.
Jahnavi Gollamudi +13 more
wiley +1 more source
Not so benign: Life-threatening hematuria from renal papillary necrosis in sickle cell trait. [PDF]
Hodgen K, Joshi P, Ngai M, Schiff J.
europepmc +1 more source
Transcranial Doppler Ultrasound Velocity Measurements in Children With Sickle Cell Disease in Kenya
ABSTRACT Background Sickle cell disease (SCD) is the most common inherited haemoglobinopathy and poses a high public health burden in Sub‐Saharan Africa. Children with sickle cell anaemia are at a highrisk of ischemic stroke, and transcranial Doppler (TCD) ultrasonography helps identify those at highest risk for primary stroke prevention.
Catherine Mwalimu +9 more
wiley +1 more source
Lights, camera, occlusion! watch sickle cells in real time. [PDF]
Gurkan UA.
europepmc +1 more source
ABSTRACT Aim Cognitive deficits are commonly reported in patients with sickle cell disease (SCD). Dietary micronutrient intake is a potential modifiable risk factor whose relationship with cognition in SCD patients remains poorly characterised. This study aimed to determine the association between dietary micronutrient intake and cognition among these ...
Albert Dennis Kegya +4 more
wiley +1 more source
Genetic variants in red blood cell adhesion-related genes influence the severity of sickle cell anemia in a malaria-endemic region : Short title: Genetic variants in red blood cell adhesion-related genes in sickle cell anemia. [PDF]
Matos I +6 more
europepmc +1 more source
ABSTRACT Rush Medical College implemented a new, integrated pre‐clerkship curriculum. Pharmacology was integrated with other basic sciences into a flipped, small‐group, case‐based structure. This report describes the main features of the pharmacology curriculum for pharmacology directors to have a template.
Brinda Desai Bradaric +3 more
wiley +1 more source
Serum ferritin in Yemeni patients with sickle cell anemia: Association with sociodemographic factors and hematological profiles. [PDF]
Al-Shami A +4 more
europepmc +1 more source

