Results 111 to 120 of about 5,052,415 (279)
Cerebral Blood Transit in Sickle Cell Anemia. [PDF]
ABSTRACT Background Sickle cell anemia (SCA) patients upregulate cerebral blood flow to compensate for decreased arterial oxygen content. Such hyperemic conditions can manifest as venous hyperintense signal on arterial spin labeling (ASL) MRI, which may reflect faster capillary blood transit, altered oxygen extraction fraction (OEF), and infarct risk ...
Richerson WT +10 more
europepmc +2 more sources
Interview with Louvenia Barksdale - OH 325 [PDF]
This collection includes an interview of Louvenia D. Barksdale (1913-1990), who founded the Sickle Cell Foundation in 1974 (which was renamed the L.D. Barksdale Sickle Cell Anemia Foundation in her honor). In this interview, Ms.
Barksdale, Louvenia Delores +1 more
core +1 more source
Abstract Arterial shear‐mediated vasodilation is a well‐established measure of endothelial function and serves as a critical biomarker for cardiovascular disease risk. Endothelial function can be measured using a variety of experimental methodologies; however, the most widely adopted technique is ultrasound‐based flow‐mediated dilation (FMD), in which ...
Yi Zhen Bao +4 more
wiley +1 more source
Mission: To improve quality of life, life expectancy, and health among people living with sickle cell disease (SCD)
core +1 more source
Abstract figure legend Metabolic stimulation improves bioenergetics, redox state, hydration and hematologic indices of circulating erythrocytes from sickle cell mice. Retained mitochondria in circulating RBCs from sickle mice are a source of RBC ATP as mitochondria function (ETC, electron transport chain) inhibitors [rotenone, a mitochondrial complex I
Luis E. F. Almeida +4 more
wiley +1 more source
ABSTRACT Rapid advances in genomics may soon enable low‐cost predictions of children's academic potential. To ensure this knowledge is used responsibly in educational settings, stakeholders require sound genetic literacy. This study assessed genetic knowledge, perceived heritability, and genetic attitudes in preservice teachers (n = 236; 83% female ...
Belinda Wauge +2 more
wiley +1 more source
ABSTRACT Background Sickle cell disease (SCD) has undergone major changes in the last decades. Its prevalence has been steadily increasing and numerous advances have been made in the management of the disease. However, the effect in real‐life setting of these major changes is unknown, particularly in a Canadian environment. Procedure We aimed to assess
Maude Cigna +16 more
wiley +1 more source
ABSTRACT Background Secretory phospholipase A2 (sPLA2) is an inflammatory mediator linked to acute chest syndrome (ACS) in sickle cell disease (SCD), a serious complication that can develop during an acute vaso‐occlusive pain episode (VOE). Plasma sPLA2 levels have been proposed as a potential biomarker for predicting ACS onset.
Rawan Korman +10 more
wiley +1 more source
Evaluating Reproductive Health Recommendations in CPGs for Sickle Cell Disease: An Umbrella Review
ABSTRACT Background Individuals with sickle cell disease or trait (SCD/T) face significant reproductive health risks, highlighting the need to assess the best available evidence on their reproductive health needs. Objectives To assess the quality of SCD/T clinical practice guidelines and evaluate the key characteristics and quality of their ...
Lisa R. Roberts +4 more
wiley +1 more source
A Síndrome da Apneia Obstrutiva do Sono (SAOS) é definida como episódios recorrentes de obstrução completa ou parcial das vias aéreas superiores que ocorrem durante o sono.
Cristina Salles +2 more
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