Results 91 to 100 of about 71,196 (274)
The Journal of Emergency Medicine, 1988 Sickle-cell anemia is a common disease, affecting more than 50,000 blacks in the United States. Since 1970 the morbidity and mortality have improved, with patients surviving well into their fourth decade. This article discusses the spectrum of serious complications of sickle-cell anemia.
Resident in Emergency Medicine, Division of Emergency Medicine, Department of Surgery, University Hospital of Jacksonville, Florida, USA ( host institution ) +2 more
openaire +3 more sources
British Journal of Haematology, EarlyView.Summary Individuals with sickle cell anaemia (SCA) exhibit significant clinical heterogeneity influenced by several factors, especially fetal haemoglobin (HbF) levels. Variations in adult HbF levels are partly explained by the co‐inheritance of genetic variants that regulate globin expression.
Gabriela S. Arcanjo +13 more
wiley +1 more source
Revista Brasileira de Hematologia e HemoterapiaBackground: Individuals with sickle cell anemia may suffer symptomatic or silent cerebral infarcts leading to neurocognitive complications. This study investigated the cognitive and intellectual performance of children and adolescents with sickle cell ...
Samantha Nunes +4 more
doaj +1 more source
Sickle cell anemia: An update on diagnosis, management and prevention strategies
Indian Journal of Community and Family Medicine, 2018 Sickle cell anemia is the most common disease entity of all the monogenic disorders. This is an autosomal recessive disorder. HbS polymerization, vaso-occlusion, and hemolytic anemia are central to the pathophysiology of sickle cell disease, they ...
Shruti Mishra, Gaurav Chhabra
doaj +1 more source
Fetal hemoglobin inducing factors [PDF]
, 2007 Sickle cell anemia is a heterogeneous disorder with variable severity. Initial observations showed that a high level of fetal hemoglobin (HbF) was associated with minor clinical manifestations, as HbF interferes with HbS polymerization.
Figueiredo, Maria Stella [UNIFESP]
core +3 more sources
Clinical Otolaryngology, EarlyView.ABSTRACT Objectives Sleep‐disordered breathing (SDB) and cognitive challenges are commonly observed in children living with sickle cell anaemia (SCA). This study investigated the longitudinal change in polysomnographic outcomes and the association with cognitive functions in children living with SCA.
Shifa Hamdule +5 more
wiley +1 more source
Duodenal perforation: an unusual complication of sickle cell anemia
The Pan African Medical Journal, 2014 Duodenal perforation in childhood is a rare condition with a high mortality rate if not treated surgically. Primary gastroduodenal perforation is frequently associated with peptic ulcer and exhibits a positive family history.
Can Acıpayam +5 more
doaj +1 more source
Journal of Medical Case Reports, 2018 Background Posterior reversible encephalopathy syndrome is a neurotoxic condition that occurs as a result of the failure of posterior circulatory autoregulation in response to acute changes in blood pressure.
Ehab Hanafy +5 more
doaj +1 more source
Modifiers factors of clinical severity in sickle cell anemia [PDF]
, 2007 Sickle cell anemia is a heterogeneous disorder with different degrees of clinical severity despite of being caused by a single base pair mutation (Glu6Val) of the ß-globin gene.
Figueiredo, Maria Stella
core +3 more sources
Developmental Medicine &Child Neurology, EarlyView.Neurodevelopmental screening in toddlers or preschoolers with sickle cell disease (SCD) predicts future academic deficits. Screening sensitivity for future academic deficits is highest in preschoolers with SCD. Brief neurodevelopmental screening tools can identify high risk children for early intervention. Abstract Aim To assess the predictive validity
Sarah E. Bills +5 more
wiley +1 more source