Results 71 to 80 of about 5,052,415 (279)

Sickle Cell Data Collection Program Brief : Hospital Encounters Among Adults Living With Sickle Cell Disease in Georgia 2012-2016 [PDF]

The Georgia Sickle Cell Data Collection Program (SCDC) identified 5,405 adults living with sickle cell disease in Georgia from 2012 through 2016. Adults with sickle cell disease live in almost every county throughout Georgia.Nearly nine in 10 (88%) of ...

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Predict less, prevent more: A familiar mantra for sickle cell anaemia?

British Journal of Haematology, EarlyView.
Commentary on: Sommet J, Boizeau P, Haouari Z, et al. Identification of predictive factors for reversal of cerebral vasculopathy in an original longitudinal cohort study in newborns with sickle cell anaemia. Br J Haematol. 2026 (Online ahead of print). doi: 10.1111/bjh.70726.
Charles T. Quinn
wiley   +1 more source

Duodenal perforation: an unusual complication of sickle cell anemia

The Pan African Medical Journal, 2014
Duodenal perforation in childhood is a rare condition with a high mortality rate if not treated surgically. Primary gastroduodenal perforation is frequently associated with peptic ulcer and exhibits a positive family history.
Can Acıpayam, Göliz Aldıé, Bélent Akéora, Mehmet Emin elikkaya, Hasan Aşkar, Bayram Ali Dorum   +5 more
doaj   +1 more source

Sickle Cell Disease (SCD) in California, 2016 [PDF]

We found 4,689 people with SCD were living in California in 2016.CS 310397-C2016-snapshot-sickle-cell-ca-508.pdf?deliveryName=USCDC_1391 ...

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Identification of predictive factors for reversal of cerebral vasculopathy in an original longitudinal cohort study in newborns with sickle cell anaemia

British Journal of Haematology, EarlyView.
Summary Cerebral macrovasculopathy (CV) is a major complication in children with sickle cell anaemia (SCA) and usually requires a long‐term transfusion programme (TP) to prevent stroke. This study aimed to identify factors predicting reversal of CV on TP in a single‐centre newborn cohort. Among 375 patients, 50 presented CV and received TP.
Julie Sommet, Priscilla Boizeau, Zinedine Haouari, Berengère Koehl, Monique Elmaleh, Emmanuelle Lesprit, Florence Missud, Ghislaine Ithier, Laurent Holvoet, Valentine Brousse, Christophe Delclaux, André Denjean, Suzanne Verlhac, Corinne Alberti, André Baruchel, Nathalie Couque, Malika Benkerrou   +16 more
wiley   +1 more source

Comprehensive neuropsychological evaluation of children and adolescents with sickle cell anemia: a hospital-based sample

Revista Brasileira de Hematologia e Hemoterapia
Background: Individuals with sickle cell anemia may suffer symptomatic or silent cerebral infarcts leading to neurocognitive complications. This study investigated the cognitive and intellectual performance of children and adolescents with sickle cell ...
Samantha Nunes, Nayara Argollo, Marivania Mota, Camilo Vieira, Eduardo Pondé de Sena   +4 more
doaj   +1 more source

Sickle cell anemia: An update on diagnosis, management and prevention strategies

Indian Journal of Community and Family Medicine, 2018
Sickle cell anemia is the most common disease entity of all the monogenic disorders. This is an autosomal recessive disorder. HbS polymerization, vaso-occlusion, and hemolytic anemia are central to the pathophysiology of sickle cell disease, they ...
Shruti Mishra, Gaurav Chhabra
doaj   +1 more source

Posterior reversible encephalopathy syndrome secondary to asymptomatic poststreptococcal glomerulonephritis in a child with sickle cell anemia: a case report

Journal of Medical Case Reports, 2018
Background Posterior reversible encephalopathy syndrome is a neurotoxic condition that occurs as a result of the failure of posterior circulatory autoregulation in response to acute changes in blood pressure.
Ehab Hanafy, Duaa Alshareef, Suhaila Osman, Abdullah Al Jabri, Faisal Nazim, Gihan Mahmoud   +5 more
doaj   +1 more source

Genetic association of fetal-hemoglobin levels in individuals with sickle cell disease in Tanzania maps to conserved regulatory elements within the MYB core enhancer. [PDF]

, 2015
BACKGROUND: Common genetic variants residing near upstream regulatory elements for MYB, the gene encoding transcription factor cMYB, promote the persistence of fetal hemoglobin (HbF) into adulthood. While they have no consequences in healthy individuals,
Soka, Deogratius, Harvest Mariki, Menzel, Stephan, Jeffrey C Barrett, Mariki, Harvest, Helen Rooks, Bruno Mmbando, Menzel, Stephan; id_orcid, Mmbando, Bruno, Tarjinder Singh, Stephan Menzel, Barrett, Jeffrey C., Sharon E Cox, Singh, Tarjinder, Mtatiro, Siana N, Barrett, Jeffrey C, Thein, Swee Lay, Deogratius Soka, Swee Lay Thein, Julie Makani, Mtatiro, Siana N., Siana N Mtatiro, Cox, Sharon E, Rooks, Helen, Mgaya, Josephine, Makani, Julie, Josephine Mgaya, Cox, Sharon E.   +27 more
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Parvovirus B19 infections in paediatric sickle cell disease patients: Genotype and hydroxyurea treatment influence disease severity

British Journal of Haematology, EarlyView.
Summary In patients with sickle cell disease (SCD), parvovirus B19 infection (B19V) leads to acute anaemia (aplastic crisis), but may also be associated with other serious complications. We retrospectively analysed clinical data from paediatric SCD patients with B19V infections between 2023 and 2025, including symptoms, laboratory parameters ...
Matthias Bleeke, Arne Simon, Beate Winkler, Sabine Heine, Anna Eichinger, Ulrich von Both, Meinolf Siepermann, Sonya El Amouri, Arndt Borkhardt, Yvonne Pritschow, Wolfgang Novak, Michael Dworzak, Sarah Goretzki, Clara Held, Karin Beutel, Franziska Gams, Henriette Rudolph, Leila Koscher, Piet E. Beusker, Eckard Hamelmann, Stefan Weichert, Svenja Häuser, Maximilian Mauritz, Malik Aydin, Verena Wiegering, Regine Grosse, Rainer Misgeld, Martina Stiefel, Nicole Töpfner, Uta Falke, Lara Imhof, Laura Tagliaferri, Daniel Ebrahimi‐Fakhari, Andreas Groll, Marion Appel, Nora Naumann‐Bartsch, Michaela Nathrath, Olaf Beck, Solvej Heidtmann, Philipp Tischer, Ulf Schulze‐Sturm, Urs Mücke, Holger Cario   +42 more
wiley   +1 more source