Results 61 to 70 of about 71,196 (274)

Liver Cirrhosis in a Patient with Sickle Cell Trait (Hb Sβ+ Thalassemia) without Other Known Causes of Hepatic Disease

Case Reports in Gastroenterology, 2009
Liver involvement in patients with sickle cell anemia/trait includes a wide range of alterations, from mild liver function test abnormalities to cirrhosis and acute liver failure. Approximately 15–30% of patients with sickle cell anemia present cirrhosis
Luca Santi, Giancarlo Montanari, Sonia Berardi, Corrado Patti, Marta Frigerio, Claudia Sama, Paolo Caraceni, Mauro Bernardi   +7 more
doaj   +1 more source

Análise do polimorfismo TA6/TA7 na região promotora do gene UGT1A1, em pacientes com anemia e traço falciforme de dois hospitais da cidade de Porto Alegre – RS [PDF]

, 2011
A doença de células falciformes é uma anemia hemolítica crônica de caráter autossômico recessivo, causada por uma mutação pontual no cromossomo 11. Esta mutação provoca a substituição de um ácido glutâmico por uma valina na posição seis da cadeia da ...
Antunes, Liana
core  

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor, Takanobu Nadai, Kei Irie, Wen Rui Tan, Sanjana Parikh, Anhar Hosawi, Matthijs W. van Hoogdalem, Ronaldo Morales Junior, Sonya Tang Girdwood, Abbie D. Leino, Kana Mizuno, Alexander A. Vinks, Tomoyuki Mizuno   +12 more
wiley   +1 more source

Nutritional Potential, Phytochemical Content, In Vivo Antioxidant, and Antanemic Potential of Musa paradisiaca Flower

Food Chemistry International, EarlyView.
After collecting Musa paradisiaca leaves, some were dried and others were used to produce aqueous extracts. The extracts and powders were characterized and then administered to rats made anaemic by PHZ. After 14 days of administration of the two samples, the rats were euthanized and it was observed that after 9 days of treatment, the aqueous extract ...
Josée Rebeca Nombo, Jethro Roland Misse Ngangue Ekwala, Somon Régine Tuem, Stéphano Tene Tambo, Merlin Ngafon Nchoutpouen, Valery Jean François Nsoga, Jules Christophe Koule Manz, Jordan Mekui Nwotue, Mathieu Ndomou   +8 more
wiley   +1 more source

Functional status of women with and without potentially life‐threatening maternal conditions after 6 months postpartum: A cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The aim of this study was to evaluate the impact of potentially life‐threatening maternal conditions (PLTCs) on functional disability at 6 months postpartum. Methods This prospective cohort study was done at 10 hospitals in Tigray, northern Ethiopia. A total of 1027 postpartum women (341 with PLTCs and 686 without) were enrolled into
Fitiwi Tinsae Baykemagn, Girmatsion Fisseha Abreha, Yibrah Berhe Zelelow, Alemayehu Bayray Kahsay   +3 more
wiley   +1 more source

Positive depression screening and associated factors among children with sickle cell anemia attending a tertiary hospital in Mwanza, Tanzania: A Cross-sectional study

Journal of Affective Disorders Reports
Background: Depression is an increasingly important public health concern among children, particularly those living with chronic illnesses, including sickle cell anemia.
Eunice H. Barnabas, Matiko Mwita, Rogatus M. Kabyemera, Emmanuela E. Ambrose   +3 more
doaj   +1 more source

Of pools, oceans, and the Dead Sea. [PDF]

, 2017
In a comprehensive study in this issue of Blood, Carden and colleagues describe the importance of the tonicity of IV fluids used in the treatment of patients with sickle cell disease (SCD) during vaso-occlusive crises (VOCs).
Ballas, Samir K.
core   +2 more sources

Immune Imbalance in Sickle Cell Anemia: Flow Cytometric Insights Into Regulatory T Cells and Neutrophil Dynamics

Journal of Clinical Laboratory Analysis, EarlyView.
Flow cytometric analysis in sickle cell anemia reveals preserved Treg frequency despite decreased CD25 expression and increased neutrophil activity, highlighting a complex immune imbalance. The proportions of both neutrophil and lymphocyte cells have been shown to be a reliable predictor of CD3+ T cell levels, thus emphasizing the importance of innate ...
Rukiye Ölçüoğlu, Funda Tanrıkulu, Sevtap Kılınç, Eda Çakmak, Süheyl Asma, Can Boğa, Hakan Özdoğu, İlknur Pamuk   +7 more
wiley   +1 more source

Reversibility of Red blood Cell deformation

, 2011
The ability of cells to undergo reversible shape changes is often crucial to their survival. For Red Blood Cells (RBCs), irreversible alteration of the cell shape and flexibility often causes anemia.
C. T. Noguchi, G. Lim, H. Goldstein, L. D. Landau, Maria Zeitz, P. Sens   +5 more
core   +3 more sources

Compound Heterozygosity for Hemoglobin S and Hemoglobin LuLu Island

American Journal of Hematology, EarlyView.
Dana Lewis, Thomas Lofaro, Laura Fraser, Sheana Wijemanne, Barbara J. Bain   +4 more
wiley   +1 more source