Results 41 to 50 of about 71,196 (274)

Hematological and hemorheological determinants of the six-minute walk test performance in children with sickle cell anemia. [PDF]

PLoS ONE, 2013
The six-minute walk test is a well-established submaximal exercise reflecting the functional status and the clinical severity of sickle cell patients. The aim of the present cross-sectional study was to investigate the biological determinants of the six ...
Xavier Waltz, Marc Romana, Marie-Dominique Hardy-Dessources, Yann Lamarre, Lydia Divialle-Doumdo, Marie Petras, Vanessa Tarer, Régine Hierso, Kizzy-Clara Baltyde, Benoît Tressières, Marie-Laure Lalanne-Mistrih, Fréderic Maillard, Olivier Hue, Maryse Etienne-Julan, Philippe Connes   +14 more
doaj   +1 more source

Lack of mortality in 22 children with sickle cell anemia and severe malarial anemia [PDF]

, 2017
Retrospective studies suggest that there is high mortality in children with sickle cell anemia (SCA) and severe malaria. We assessed mortality in Ugandan children with severe malarial anemia (SMA, n = 232) or cerebral malaria (CM, n = 267) by sickle cell
Bangirana, Paul, Idro, Richard, John, Chandy C., Namazzi, Ruth, Opoka, Robert O., Shabani, Estela   +5 more
core   +1 more source

Natural History of Chronic Kidney Disease in Sickle Cell Disease

American Journal of Hematology, EarlyView.
ABSTRACT Kidney complications, referred to as nephropathy, develop early in sickle cell disease (SCD). In addition to its known morbidity, abundant data show that chronic kidney disease (CKD) is associated with an increased mortality risk in SCD. Increasing evidence suggests that the natural history of SCD nephropathy is progressive. Initial glomerular
Kenneth I. Ataga
wiley   +1 more source

Haptoglobin gene polymorphisms and interleukin-6 and -8 levels in patients with sickle cell anemia

Revista Brasileira de Hematologia e Hemoterapia, 2015
BACKGROUND: Haptoglobin genotypes, and interleukin-6 and -8 participate in the pathophysiology of sickle cell anemia. The expression of cytokines is regulated by genetic mechanisms however the effect of haptoglobin polymorphisms on these cytokines is not
Bruna Spinella Pierrot-Gallo, Perla Vicari, Sandra Satiko Matsuda, Samuel Ademola Adegoke, Grazielle Mecabo, Maria Stella Figueiredo   +5 more
doaj   +1 more source

Specifying sickle cell disease interventions: A study protocol of the Sickle Cell Disease Implementation Consortium (SCDIC) [PDF]

, 2018
Background Sickle cell disease (SCD) is an inherited blood disorder that results in a lifetime of anemia, severe pain, and end-organ damage that can lead to premature mortality.
Baumann, Ana A, Belle, Steven H, James, Aimee, King, Allison A, Sickle Cell Disease Implementation Consortium,   +4 more
core   +2 more sources

Relationship between pulmonary and cardiac abnormalities in sickle cell disease: implications for the management of patients

Revista Brasileira de Hematologia e Hemoterapia, 2016
Objective: To evaluate the association between clinical, pulmonary, and cardiovascular findings in patients with sickle cell disease and, secondarily, to compare these findings between sickle cell anemia patients and those with other sickle cell diseases.
Maria Christina Paixão Maioli, Andrea Ribeiro Soares, Ricardo Bedirian, Ursula David Alves, Cirlene de Lima Marinho, Agnaldo José Lopes   +5 more
doaj   +1 more source

Sickle cell trait and risk of cognitive impairment in African-Americans: The REGARDS cohort [PDF]

, 2019
Background: Sickle cell anemia may be associated with cognitive dysfunction, and some complications of sickle cell anemia might affect those with sickle cell trait (SCT), so we hypothesized that SCT is a risk factor for cognitive impairment. Methods:
Cahill, Christina R., Cushman, Mary, Hyacinth, Hyacinth I., Irvin, Marguerite Ryan, Judd, Suzanne E., Leach, Justin M., Manly, Jennifer, McClure, Leslie A., Naik, Rakhi, Unverzagt, Frederick, Wadley, Virginia G., Winkler, Cheryl, Zakai, Neil A.   +12 more
core   +1 more source

A Novel Plasma Heme Assay Reveals Disease Severity in Beta‐Thalassemia and Sickle Cell Anemia

American Journal of Hematology, EarlyView.
ABSTRACT Anemia results from imbalanced hemoglobin or red blood cell production and clearance. Hemolytic anemia, caused by premature red blood cell removal, can be intravascular (in blood) or extravascular (erythrophagocytosis). Hemolysis is common in Sickle Cell Disease (SCD) and Beta‐Thalassemia anemia (β‐thalassemia), the most prevalent inherited ...
Laurent Kiger, Nicolas Hebert, Laura Bencheikh, Vincent Malcor Deydier de Pierrefeu, Anne‐Laure Pham Hung d’Alexandry d’Orengiani, Sandia Adypagavane, Meghan Perkins, Laura Matabishi‐Bibi, France Pirenne, Claire Berquet, Stephane Moutereau, Serge Pissard, Frédéric Galactéros, Michael C. Marden, Pablo Bartolucci   +14 more
wiley   +1 more source

Coexistent sickle cell anemia and autoimmune hemolytic anemia in two adolescents [PDF]

Einstein (São Paulo)
The development of alloantibodies or autoantibodies is a complication observed in sickle cell disease. Autoimmunization occurs in 7.6-12% of chronically or intermittently transfused patients with sickle cell disease; however, the clinical implications of
Vinícius Reis Soares, Bruna Paccola Blanco, Carla Luana Dinardo, Marlene Pereira Garanito   +3 more
doaj   +1 more source

Coexisting Sickle Cell Anemia and Sarcoidosis: A Management Conundrum! [PDF]

, 2017
Sickle cell disease and Sarcoidosis are conditions that are more common in the African American population. In this report we share an unfortunate patient who had hepatic sarcoidosis but could not receive steroids since that precipitated acute liver ...
Gollahalli, Nagesh S., Nutan, FNU
core   +3 more sources