Results 21 to 30 of about 5,052,415 (279)

Bacteraemia in Kenyan children with sickle-cell anaemia: a retrospective cohort and case-control study. [PDF]

, 2009
BACKGROUND: In sub-Saharan Africa, more than 90% of children with sickle-cell anaemia die before the diagnosis can be made. The causes of death are poorly documented, but bacterial sepsis is probably important.
Uyoga, Sophie, Berkley, James, Macharia, Alex, McAuley, Charlotte F, Opi, DH, Kevin Marsh, J Anthony G Scott, Mwarumba, Salim, Berkley, James A, Ndila, C, Scott, John, Carolyne Ndila, Berkley, JA, Thomas N Williams, Sophie Uyoga, Williams, TN, Makani, J, James A Berkley, Sharif, SK, McAuley, CF, Daniel H Opi, Mwarumba, S, Uyoga, S, Macharia, A, Albert Komba, Marsh, K, Scott, JA, Charlotte F McAuley, Sharif, Shahnaaz K, Scott, J Anthony G, Williams, Thomas N, Julie Makani, Ndiritu, Moses N, Salim Mwarumba, Moses N Ndiritu, Komba, Albert, Williams, Thomas, Komba, A, Opi, Daniel H, Makani, Julie, Marsh, Kevin, Ndiritu, MN, Alex Macharia, Shahnaaz K Sharif, Ndila, Carolyne   +44 more
core   +1 more source

Hematological and Genetic Predictors of Daytime Hemoglobin Saturation in Tanzanian Children with and without Sickle Cell Anemia. [PDF]

, 2013
Low hemoglobin oxygen saturation (SpO2) is common in Sickle Cell Anemia (SCA) and associated with complications including stroke, although determinants remain unknown.
Cox, Sharon E, Newton, Charles R, Makani, Julie, Prentice, Andrew M, Kirkham, Fenella J   +4 more
core   +1 more source

Murine models of sickle cell disease and beta‐thalassemia demonstrate pulmonary hypertension with distinctive features

Pulmonary Circulation, 2021
Sickle cell anemia and β‐thalassemia intermedia are very different genetically determined hemoglobinopathies predisposing to pulmonary hypertension. The etiologies responsible for the associated development of pulmonary hypertension in both diseases are ...
Paul W. Buehler, Delaney Swindle, David I. Pak, Mehdi A. Fini, Kathryn Hassell, Rachelle Nuss, Rebecca B. Wilkerson, Angelo D’Alessandro, David C. Irwin   +8 more
doaj   +1 more source

Impact of Sickle Cell Hemoglobin Genotypes on Clinical Outcomes Among <i>Plasmodium falciparum</i> Malaria Patients in Luanda, Angola. [PDF]

Health Sci Rep
ABSTRACT Background Sickle cell anemia (SCA) may influence malaria susceptibility and clinical outcomes in endemic regions. However, the interaction between hemoglobin genotypes and malaria severity remain poorly defined in endemic African settings, particulary in Angola, where SCA and malaria impose a substantial public health burden.
Sebastião CS, Ekundi-Valentim E, Cassinela E, Sacomboio E.   +3 more
europepmc   +2 more sources

Machine Learning Approach for Classification of Sickle Cell Anemia in Teenagers Based on Bayesian Network

Journal of Information Systems and Informatics, 2023
In this study, we employed a Bayesian network approach for the classification of sickle cell anemia in teenagers based on their medical data. Sickle cell anemia is a hereditary blood disorder characterized by the presence of abnormal hemoglobin, leading
Blessing Ekong, Otuekong Ekong, Abasiama Silas, Anthony Effiong Edet, Bright William   +4 more
doaj   +1 more source

Prevalence of Haemoglobine s in Araraquara-SP Population.

Revista Brasileira Multidisciplinar - ReBraM /Brazilian Multidisciplinay Journal, 2015
The Sickle Cell Anemia is a genetic hemoglobionopathy, characterized by an alteration in the hemoglobin molecule struture (HbA1), called hemoglobin S (HbS), which causes a distortion in the erythocytes structure, changing from spherical shape to sickle ...
Bruno Rocha de Jesus, Heloise Brait Rin, Elza Regina Manzolli Leite, Amauri Antiquera Leite, Miriane da Costa Gileno   +4 more
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Neuroimaging Biomarkers in Paediatric Sickle Cell Disease [PDF]

, 2015
Sickle Cell Disease (SCD) is a collection of genetic haemoglobinopathies, the most common and severe being homozygous sickle cell anaemia. In the UK, it has been estimated that 1 in 2000 children are born with SCD. The disease is characterised by chronic
Kawadler, JM
core  

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Self-resolution of spontaneous epidural hematoma in sickle cell anemia: A case report

Radiology Case Reports
Spontaneous epidural hematoma is a rare and dangerous complication of sickle cell anemia which typically requires surgical management. We present a rare case of a patient with sickle cell anemia and intracranial spontaneous epidural hematoma which ...
Shruti Kumari, MD, Grayson H. Hooper, DO, Ameya Nayate, MD   +2 more
doaj   +1 more source