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Prevalence of sickle cell disease and sickle cell trait in national neonatal screening studies
Sickle cell anemia is the best known hereditary blood disorder; there are serious complications associated with the condition. Diagnosis and early intervention reduce morbidity and mortality.
Luciana Garcia Lervolino +5 more
doaj +1 more source
Nutritional status of young children with inherited blood disorders in western Kenya. [PDF]
To determine the association between a range of inherited blood disorders and indicators of poor nutrition, we analyzed data from a population-based, cross-sectional survey of 882 children 6–35 months of age in western Kenya.
Ruth, LJ +4 more
core +1 more source
Treatment of severe malaria with artemisinin derivatives in patients with comorbid conditions such as sickle cell anemia must be considered with precaution.
Abdulrahman Hummadi +3 more
doaj +1 more source
Prevalence of Inherited Hemoglobin Disorders and Relationships with Anemia and Micronutrient Status among Children in Yaoundé and Douala, Cameroon. [PDF]
Information on the etiology of anemia is necessary to design effective anemia control programs. Our objective was to measure the prevalence of inherited hemoglobin disorders (IHD) in a representative sample of children in urban Cameroon, and examine the ...
Brown, Kenneth H +8 more
core +1 more source
The Evolving Pharmacotherapeutic Landscape for the Treatment of Sickle Cell Disease. [PDF]
Sickle cell disease (SCD) is an extremely heterogeneous disease that has been associated with global morbidity and early mortality. More effective and inexpensive therapies are needed.
Ballas, Samir K
core +1 more source
The kidney in sickle cell anemia
In 1910, Herrick described the first authentic case of sickle cell disease in a young student from Grenada in the West Indies [1]. He records that he was “uncertain whether the blood picture represented merely a freakish poikilocytosis or is dependent on some peculiar physical or chemical condition of the blood or is characteristic of some particular ...
Alleyne, George A.O. +4 more
openaire +2 more sources
Background Recent evidence suggests that red blood cell aggregation and the ratio of hematocrit to blood viscosity (HVR), an index of the oxygen transport potential of blood, might considerably modulate blood flow dynamics in the microcirculation.
Julien Tripette +10 more
doaj +1 more source
In this study, we employed a Bayesian network approach for the classification of sickle cell anemia in teenagers based on their medical data. Sickle cell anemia is a hereditary blood disorder characterized by the presence of abnormal hemoglobin, leading
Blessing Ekong +4 more
doaj +1 more source
Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia [PDF]
Hydroxyurea treatment is recommended for children with sickle cell anemia (SCA) living in high-resource malaria-free regions, but its safety and efficacy in malaria-endemic sub-Saharan Africa, where the greatest sickle-cell burden exists, remain unknown.
Hodges, James S. +8 more
core +2 more sources
Prevalence of Haemoglobine s in Araraquara-SP Population.
The Sickle Cell Anemia is a genetic hemoglobionopathy, characterized by an alteration in the hemoglobin molecule struture (HbA1), called hemoglobin S (HbS), which causes a distortion in the erythocytes structure, changing from spherical shape to sickle ...
Bruno Rocha de Jesus +4 more
doaj +1 more source

