Results 21 to 30 of about 35,347 (227)

Prevalence of Haemoglobine s in Araraquara-SP Population.

open access: yesRevista Brasileira Multidisciplinar - ReBraM /Brazilian Multidisciplinay Journal, 2015
The Sickle Cell Anemia is a genetic hemoglobionopathy, characterized by an alteration in the hemoglobin molecule struture (HbA1), called hemoglobin S (HbS), which causes a distortion in the erythocytes structure, changing from spherical shape to sickle ...
Bruno Rocha de Jesus   +4 more
doaj   +1 more source

Machine Learning Approach for Classification of Sickle Cell Anemia in Teenagers Based on Bayesian Network

open access: yesJournal of Information Systems and Informatics, 2023
In this study, we employed a Bayesian network approach for the classification of sickle cell anemia in teenagers based on their medical data. Sickle cell anemia is a hereditary blood disorder characterized by the presence of abnormal hemoglobin, leading
Blessing Ekong   +4 more
doaj   +1 more source

Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge   +6 more
wiley   +1 more source

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte   +5 more
wiley   +1 more source

Self-resolution of spontaneous epidural hematoma in sickle cell anemia: A case report

open access: yesRadiology Case Reports
Spontaneous epidural hematoma is a rare and dangerous complication of sickle cell anemia which typically requires surgical management. We present a rare case of a patient with sickle cell anemia and intracranial spontaneous epidural hematoma which ...
Shruti Kumari, MD   +2 more
doaj   +1 more source

Inpatient Exposure, Confidence, and Knowledge in Pediatric Hematology/Oncology: Evaluating General Pediatric Residents During 2025 ACGME Curriculum Change

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background General pediatricians often evaluate hematologic and oncologic presentations before subspecialty consultation, yet the 2025 Accreditation Council for Graduate Medical Education (ACGME) pediatric requirements reduce inpatient pediatric hematology/oncology (PHO) time, raising questions about resident readiness.
Colburn Yu, Rohini Jain
wiley   +1 more source

Hemorheological risk factors of acute chest syndrome and painful vaso-occlusive crisis in children with sickle cell disease

open access: yesHaematologica, 2012
Background Little is known about the effects of blood rheology on the occurrence of acute chest syndrome and painful vaso-occlusive crises in children with sickle cell anemia and hemoglobin SC disease.Design and Methods To address this issue, steady ...
Yann Lamarre   +13 more
doaj   +1 more source

Genetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian population [PDF]

open access: yesGenetics and Molecular Biology, 2020
Fetal hemoglobin (HbF) is a determining factor for the development of sickle cell anemia. High HbF levels lower the intensity of symptoms of this disease. HbF levels can vary in patients with sickle cell anemia and individuals without the disease.
Cristian Fong   +2 more
doaj   +1 more source

Improvement of Sickle Cell Disease Care Mitigates the Healthcare Utilization Induced by Increased Prevalence: Experience of a Tertiary Pediatric Center

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) has undergone major changes in the last decades. Its prevalence has been steadily increasing and numerous advances have been made in the management of the disease. However, the effect in real‐life setting of these major changes is unknown, particularly in a Canadian environment. Procedure We aimed to assess
Maude Cigna   +16 more
wiley   +1 more source

Hematological and hemorheological determinants of the six-minute walk test performance in children with sickle cell anemia. [PDF]

open access: yesPLoS ONE, 2013
The six-minute walk test is a well-established submaximal exercise reflecting the functional status and the clinical severity of sickle cell patients. The aim of the present cross-sectional study was to investigate the biological determinants of the six ...
Xavier Waltz   +14 more
doaj   +1 more source

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