Results 11 to 20 of about 5,052,415 (279)

Sexuality and sickle cell anemia

Revista Brasileira de Hematologia e Hemoterapia, 2013
BACKGROUND: Sickle cell disease, the most common hereditary blood disease in the world, is the result of an atypical hemoglobin called S (Hb S) which, when homozygous (Hb SS) is the cause of sickle cell anemia.
Viviane de Almeida Côbo, Cibele Alves Chapadeiro, João Batista Ribeiro, Helio Moraes-Souza, Paulo Roberto Juliano Martins   +4 more
doaj   +5 more sources

Feasibility and utility of a sickle cell disease registry for research and patient management [PDF]

, 2009
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis aimed to evaluate the feasibility and utility of a sickle cell disease registry for clinical patient management and research.
Gilmore, Annette
core   +7 more sources

Role of sickling crisis with serum zinc in children with sickle cell anemia

Advanced Medical Journal, 2022
Background and objectives: Sickle cell anemia causes painful crises by the occlusion of small blood vessels by spontaneous intravascular sickling. The aim of this study is to determine the possible association of Zinc deficiency with painful crises ...
Bahzad Khalid Sharaf, Akrem Mohammad Atrushi   +1 more
doaj   +1 more source

Knowledge and DdeI Based Confirmation of Sickle Cell Anemia Among the Tharu Community

Journal of Nepal Health Research Council, 2022
Background: Sickle cell anemia is an inherited blood disorder caused due to a point mutation at the sixth codon of the ?-globin gene of both alleles. Sickle cell traits occur when the mutation is in one of the two alleles of the ?-globin genes.
Sajani Ghaju, Karan Khadayat, Raju Shrestha, Salan Ghaju, Trishna Manandhar, Bishnu P. Marasini   +5 more
doaj   +1 more source

Sickle Cell Anemia [PDF]

RadioGraphics, 2001
Sickle cell anemia (SCA) is a disease caused by production of abnormal hemoglobin, which binds with other abnormal hemoglobin molecules within the red blood cell to cause rigid deformation of the cell. This deformation impairs the ability of the cell to pass through small vascular channels; sludging and congestion of vascular beds may result, followed ...
G J, Lonergan, D B, Cline, S L, Abbondanzo   +2 more
openaire   +2 more sources

Splenic sequestration and infarction upon exposure to high altitude in adult patients with sickle cell anemia

Journal of Applied Hematology, 2023
Adult patients with sickle cell disease usually have atrophied spleens due to autosplenectomy, and only rarely have complications related to the spleen, such as splenic sequestration and infarctions.
Husain Alkhaldy, Mortadah Alsalman, Mariyyah Almuhaini, Renad Alshehri, Samar Almusaad, Wejdan Al-Qahtani, Tamer A Samih, Mohammed Makkawi   +7 more
doaj   +1 more source

HEMATOPOIETIC STEM CELL TRANSPLANTATION IN THALASSEMIA AND SICKLE CELL DISEASE: EXPERIENCE OF MEDITERRANEAN INSTITUTE OF HEMATOLOGY IN A MULTI-ETHNIC POPULATION.

Mediterranean Journal of Hematology and Infectious Diseases, 2009
Hematopoietic stem cell transplantation (HSCT) still remains the only definitive cure currently available for patients with thalassemia and sickle cell anemia.
Marco Marziali, Antonella Isgrò, Javid Gaziev, Guido Lucarelli   +3 more
doaj   +1 more source

Treating sickle cell anemia [PDF]

Science, 2020
New drugs, stem cell transplants, and gene therapy show promise in treating sickle cell ...
John F, Tisdale, Swee Lay, Thein, William A, Eaton   +2 more
openaire   +2 more sources

Peripheral Red Blood Cell Split Chimerism as a Consequence of Intramedullary Selective Apoptosis of Recipient Red Blood Cells in a Case of Sickle Cell Disease

Mediterranean Journal of Hematology and Infectious Diseases, 2014
Allogeneic cellular gene therapy through hematopoietic stem cell transplantation is the only radical cure for congenital hemoglobinopathies like thalassemia and sickle cell anemia.
Marco Marziali, Antonella Isgrò, Pietro Sodani, Javid Gaziev, Daniela Fraboni, Katia Paciaroni, Cristiano Gallucci, Cecilia Alfieri, Andrea Roveda, Gioia De Angelis, Luisa Cardarelli, Michela Ribersani, Marco Andreani, Guido Lucarelli   +13 more
doaj   +1 more source

Haploidentical HSCT for hemoglobinopathies: improved outcomes with TCRαβ+/CD19+-depleted grafts

Blood Advances, 2018
: We examined outcomes of haploidentical hematopoietic cell transplantation (haplo-HCT) using T-cell receptor αβ+ (TCRαβ+)/CD19+-depleted grafts (TCR group, 14 patients) in children with hemoglobinopathies.
Javid Gaziev, Antonella Isgrò, Pietro Sodani, Katia Paciaroni, Gioia De Angelis, Marco Marziali, Michela Ribersani, Cecilia Alfieri, Alessandro Lanti, Tiziana Galluccio, Gaspare Adorno, Marco Andreani   +11 more
doaj   +1 more source