Results 41 to 50 of about 35,966 (131)

The abrupt pathological deterioration of cisplatin‐induced acute kidney injury: Emerging of a critical time point

open access: yesPharmacology Research & Perspectives, 2021
Cisplatin (CP), an anticancer drug, often causes kidney damage. However, the mechanism of CP‐induced acute kidney injury (AKI) is not completely understood.
Qin Gong   +10 more
doaj   +1 more source

Data_Sheet_1_Anemoside B4 Inhibits Vascular Smooth Muscle Cell Proliferation, Migration, and Neointimal Hyperplasia.PDF

open access: yes, 2022
Vascular smooth muscle cell (VSMC) phenotypic transformation, proliferation, and migration play a pivotal role in developing neointimal hyperplasia after vascular injury, including percutaneous transluminal angioplasty and other cardiovascular ...
Chao Zhong (2247550)   +10 more
core   +1 more source

Research progress on pharmacological actions and molecular mechanisms of Anemoside B4

open access: yes, 2022
Abstract Anemoside B4 (AB4), as an important ingredient of Chinese herb Pulsatilla Chinensis, has been used in Chinese ancient medicine for thousands of years with exact therapeutic effects of anti-inflammation and anti-tumor. Due to its high potency and low toxicity, AB4 has caused more and more attention of researchers. In this paper, we will
Tianming Lu   +5 more
openaire   +1 more source

Pharmacological activities and molecular mechanisms of Pulsatilla saponins

open access: yesChinese Medicine, 2022
Saponins are found in a variety of higher plants and display a wide range of pharmacological activities, including expectorant, anti-inflammatory, vasoprotective and antimicrobial properties. Pulsatilla chinensis (P.
Jinmiao Zhong   +3 more
doaj   +1 more source

Circulating leukotriene b4 identifies respiratory complications after trauma [PDF]

open access: yes, 2012
Background. Leukotriene B4 (LTB4), a proinflammatory lipid mediator correlates well with the acute phase of Acute Respiratory Distress Syndrome (ARDS). Therefore, LTB4-levels were investigated to determine whether they might be a useful clinical marker ...
Henrich, Dirk   +11 more
core   +1 more source

Anemoside B4 attenuates RANKL-induced osteoclastogenesis by upregulating Nrf2 and dampens ovariectomy-induced bone loss

open access: yesBiomedicine & Pharmacotherapy, 2023
Increased numbers and functional overactivity of osteoclasts are the pathological basis for bone loss diseases such as osteoporosis, which are characterized by cortical bone thinning, decreased trabecular bone quantity, and reduced bone mineral density.
Zhen Cao   +7 more
openaire   +2 more sources

Stratification by Smoking Status Reveals an Association of CHRNA5-A3-B4 Genotype with Body Mass Index in Never Smokers [PDF]

open access: yes, 2014
We previously used a single nucleotide polymorphism (SNP) in the CHRNA5-A3-B4 gene cluster associated with heaviness of smoking within smokers to confirm the causal effect of smoking in reducing body mass index (BMI) in a Mendelian randomisation analysis.
Kumari, Meena   +449 more
core   +1 more source

Intense isolectin-B4 binding in rat dorsal root ganglion neurons distinguishes c-fiber nociceptors with broad action potentials and high nav1.9 expression [PDF]

open access: yes, 2006
Binding to isolectin-B4 (IB4) and expression of tyrosine kinase A (trkA) (the high-affinity NGF receptor) have been used to define two different subgroups of nociceptive small dorsal root ganglion (DRG) neurons. We previously showed that only nociceptors
Fang, Xin, Dr.   +17 more
core   +1 more source

B4 - Brisbane Backyard Bird Box [PDF]

open access: yes, 2016
The B4 - Brisbane Backyard Bird Box is a situated, social, and gamified web based application with a dedicated recording box aimed to support wider community engagement in environmental conservation.
Brereton, Margot   +13 more
core   +1 more source

)B4 [PDF]

open access: yes, 1985
An anomalous magnetic phase diagram for (Y1-xU x)B4 has previously been reported. This system is paramagnetic for x>0.6, ferromagnetic for 0.
Z. Fisk   +5 more
core   +1 more source

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